Search Results - "OUREDNIK, JITKA"
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Protocol to optimize the Rice-Vannucci rat pup model of perinatal asphyxia to ensure predictable hypoxic-ischemic cerebral lesions
Published in STAR protocols (21-06-2024)“…The Rice-Vannucci model in rodent pups is subject to substantial loss of animals, result inconsistency, and high lab-to-lab variability in extent and…”
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The Miniature Pig as an Animal Model in Biomedical Research
Published in Annals of the New York Academy of Sciences (01-05-2005)“…: Crucial prerequisites for the development of safe preclinical protocols in biomedical research are suitable animal models that would allow for human‐related…”
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Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells
Published in Proceedings of the National Academy of Sciences - PNAS (17-07-2007)“…Stem cells have been widely assumed to be capable of replacing lost or damaged cells in a number of diseases, including Parkinson's disease (PD), in which…”
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Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons
Published in Nature biotechnology (01-11-2002)“…We investigated the hypothesis that neural stem cells (NSCs) possess an intrinsic capacity to "rescue" dysfunctional neurons in the brains of aged mice. The…”
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Functional Recovery Following Traumatic Spinal Cord Injury Mediated by a Unique Polymer Scaffold Seeded with Neural Stem Cells
Published in Proceedings of the National Academy of Sciences - PNAS (05-03-2002)“…To better direct repair following spinal cord injury (SCI), we designed an implant modeled after the intact spinal cord consisting of a multicomponent polymer…”
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Acute injury directs the migration, proliferation, and differentiation of solid organ stem cells: Evidence from the effect of hypoxia–ischemia in the CNS on clonal “reporter” neural stem cells
Published in Experimental neurology (01-05-2006)“…Clonal neural cells with stem-like features integrate appropriately into the developing and degenerating central and peripheral nervous system throughout the…”
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Plasticity of the central nervous system and formation of "auxiliary niches" after stem cell grafting: an essay
Published in Cell transplantation (01-01-2007)“…It is hoped that stem cell biology will play a major role in the treatment of a number of so far incurable diseases via transplantation therapy. Today, we know…”
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Graft-induced plasticity in the mammalian host CNS
Published in Cell transplantation (01-01-2004)“…In this review we trace back the history of an idea that takes a new approach in restorative neurotransplantation by focusing on the "multifaceted dialogue"…”
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Neural Stem/Progenitor Cells Initiate the Formation of Cellular Networks That Provide Neuroprotection by Growth Factor‐Modulated Antioxidant Expression
Published in Stem cells (Dayton, Ohio) (01-01-2008)“…Recent studies indicate that transplanted neural stem/progenitor cells (NSPs) can interact with the environment of the central nervous system and stimulate…”
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Increased “Vigilance” of Antioxidant Mechanisms in Neural Stem Cells Potentiates Their Capability to Resist Oxidative Stress
Published in Stem cells (Dayton, Ohio) (01-09-2006)“…Although the potential value of transplanted and endogenous neural stem cells (NSCs) for the treatment of the impaired central nervous system (CNS) has widely…”
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Cross‐Talk Between Stem Cells and the Dysfunctional Brain is Facilitated by Manipulating the Niche: Evidence from an Adhesion Molecule
Published in Stem cells (Dayton, Ohio) (01-11-2009)“…In the injured brain, the behavior of neural stem/progenitor cells (NSCs) is regulated by multiple converging factors encountered in the niche, which is…”
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Graft/Host Relationships in the Developing and Regenerating CNS of Mammals
Published in Annals of the New York Academy of Sciences (01-05-2005)“…: A new light was shed on the utility of neural grafts when it was recognized that donor tissues and cells offer more than a source of immature progenitors…”
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Multifaceted dialogue between graft and host in neurotransplantation
Published in Journal of neuroscience research (15-04-2004)“…Current restorative neurotransplantation research focuses mainly on the potential of the neural graft to replace damaged or missing cell populations and to…”
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Segregation of Human Neural Stem Cells in the Developing Primate Forebrain
Published in Science (American Association for the Advancement of Science) (07-09-2001)“…Many central nervous system regions at all stages of life contain neural stem cells (NSCs). We explored how these disparate NSC pools might emerge. A traceable…”
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Grafted Neural Stem Cells Shield the Host Environment from Oxidative Stress
Published in Annals of the New York Academy of Sciences (01-05-2005)“…: Here, we present our preliminary data showing that neural stem cells (NSCs) can prevent the degeneration of striatal neurons when transplanted into the CNS…”
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Published in Annals of the New York Academy of Sciences (01-05-2005)Get full text
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Preface
Published in Annals of the New York Academy of Sciences (01-05-2005)Get full text
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Preface
Published in Annals of the New York Academy of Sciences (01-05-2005)Get full text
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Stem cells: cross–talk and developmental programs
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (29-05-2004)“…The thesis advanced in this essay is that stem cells—particularly those in the nervous system—are components in a series of inborn ‘programs’ that not only…”
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Acute injury directs the migration, proliferation, and differentiation of solid organ stem cells : Evidence from the effect of hypoxia-ischemia in the CNS on clonal reporter neural stem cells: Stem/progenitor cell biology & stroke/hypoxic-ischemic cerebral injury
Published in Experimental neurology (2006)Get full text
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