Search Results - "OUAÏSSI, Mehdi"
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Pancreatic Adenocarcinoma Therapeutic Targets Revealed by Tumor-Stroma Cross-Talk Analyses in Patient-Derived Xenografts
Published in Cell reports (Cambridge) (28-11-2017)“…Preclinical models based on patient-derived xenografts have remarkable specificity in distinguishing transformed human tumor cells from non-transformed murine…”
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Further characterization of HDAC and SIRT gene expression patterns in pancreatic cancer and their relation to disease outcome
Published in PloS one (02-10-2014)“…Ductal adenocarcinoma of the pancreas is ranking 4 for patient' death from malignant disease in Western countries, with no satisfactory treatment. We…”
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Pancreaticobiliary Maljunctions in European Patients with Bile Duct Cysts: Results of the Multicenter Study of the French Surgical Association (AFC)
Published in World journal of surgery (01-02-2017)“…Background Pancreaticobiliary maljunctions (PBMs) are congenital anomalies of the junction between pancreatic and bile ducts, frequently associated with bile…”
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Only Surgical Treatment to Be Considered for Adhesive Small Bowel Obstruction: A New Paradigm
Published in Gastroenterology research and practice (01-01-2018)“…Background. Adhesive small bowel obstruction (SBO) represents a heavy burden in healthcare systems worldwide and is associated with significant morbidity and…”
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HDAC gene expression in pancreatic tumor cell lines following treatment with the HDAC inhibitors panobinostat (LBH589) and trichostatine (TSA)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-03-2012)“…Abstract Background In this study, the effect of LBH589 and trichostatin (TSA), a standard histone deacetylase inhibitor (HDACi) toward the growth of…”
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Predictors of Long-Term Survival Following Resection for Ampullary Carcinoma
Published in Pancreas (01-07-2014)Get full text
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Total laparoscopic ileal pouch-anal anastomosis : prospective series of 82 patients
Published in Surgical endoscopy (01-01-2009)Get full text
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Performance of different nebulizers in clinical use for Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC)
Published in PloS one (02-05-2024)“…Technical ex-vivo comparison of commercial nebulizer nozzles used for Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC). The performance of four…”
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Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma
Published in Proceedings of the National Academy of Sciences - PNAS (24-02-2015)“…The malignant progression of pancreatic ductal adenocarcinoma (PDAC) is accompanied by a profound desmoplasia, which forces proliferating tumor cells to…”
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Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness
Published in The Journal of clinical investigation (01-11-2016)“…The intratumoral microenvironment, or stroma, is of major importance in the pathobiology of pancreatic ductal adenocarcinoma (PDA), and specific conditions in…”
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LIF Drives Neural Remodeling in Pancreatic Cancer and Offers a New Candidate Biomarker
Published in Cancer research (Chicago, Ill.) (15-02-2018)“…Pancreatic ductal adenocarcinoma (PDAC) is characterized by extensive stroma and pathogenic modifications to the peripheral nervous system that elevate…”
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What Is the Optimal Elective Colectomy for Splenic Flexure Cancer: End of the Debate? A Multicenter Study From the GRECCAR Group With a Propensity Score Analysis
Published in Diseases of the colon & rectum (01-01-2022)“…The optimal elective colectomy in patients with splenic flexure tumor is debated. This study aimed to compare splenic flexure colectomy, left hemicolectomy,…”
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Clinical Outcome for Patients Managed with Low-Dose Cisplatin and Doxorubicin Delivered as Pressurized Intraperitoneal Aerosol Chemotherapy for Unresectable Peritoneal Metastases of Gastric Cancer
Published in Annals of surgical oncology (2022)“…Background Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is increasingly used to manage gastric cancer peritoneal metastasis (GCPM). Methods This…”
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Brain metastases from colorectal cancer: characteristics and management
Published in ANZ journal of surgery (01-03-2018)“…Background Brain metastases (BMs) are the most common intracranial neoplasms in adults, but they rarely arise from colorectal cancer (CRC). The objective of…”
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Pressurized Intraperitoneal Aerosol Chemotherapy for Colorectal Peritoneal Metastases
Published in Annals of surgical oncology (01-09-2021)“…Background The benefit of repetitive PIPAC specifically in CPM patients has yet to be demonstrated in terms of oncological and functional outcomes. Objective…”
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Long term outcome of anastomotic leakage in patients undergoing low anterior resection for rectal cancer
Published in BMC cancer (20-08-2020)“…The influence of anastomotic leakage (AL) on local recurrence rates and survival in rectal cancer remains controversial. The aim of this study was to analyze…”
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Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for the treatment of malignant mesothelioma
Published in BMC cancer (18-04-2018)“…Patients with recurrent malignant epithelioid mesothelioma (MM) after surgery and standard chemotherapy with cisplatin and pemetrexed have limited treatment…”
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Complete Pathological Response Following Radiochemotherapy for Locally Advanced Rectal Cancer: Short and Long-term Outcome
Published in Anticancer research (01-09-2019)“…Preoperative radiochemotherapy (RCT) followed by total mesorectum excision has become the gold standard for locally advanced carcinoma of the low and middle…”
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Primary Thromboprophylaxis in Pancreatic Cancer Patients: Why Clinical Practice Guidelines Should Be Implemented
Published in Cancers (06-03-2020)“…Exocrine pancreatic ductal adenocarcinoma, simply referred to as pancreatic cancer (PC) has the worst prognosis of any malignancy. Despite recent advances in…”
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