Search Results - "OTVOS, J"

Subfractions and subpopulations of HDL: an update by Rizzo, M, Otvos, J, Nikolic, D, Montalto, G, Toth, P P, Banach, M

“…High-density lipoproteins (HDL) are classified as atheroprotective because they are involved in transport of cholesterol to the liver, known as "reverse…”
Get more information

Lifestyle and Metformin Treatment Favorably Influence Lipoprotein Subfraction Distribution in the Diabetes Prevention Program by Goldberg, R, Temprosa, M, Otvos, J, Brunzell, J, Marcovina, S, Mather, K, Arakaki, R, Watson, K, Horton, E, Barrett-Connor, E

“…Context: Although intensive lifestyle change (ILS) and metformin reduce diabetes incidence in subjects with impaired glucose tolerance (IGT), their effects on…”
Get full text

GlycA, a novel marker of inflammation, is elevated in systemic lupus erythematosus by Chung, C P, Ormseth, M J, Connelly, M A, Oeser, A, Solus, J F, Otvos, J D, Raggi, P, Stein, C M

“…Background GlycA is a novel marker of systemic inflammation detected by nuclear magnetic resonance (NMR) spectroscopy. In the general population, GlycA is…”
Get full text

Novel measures of inflammation and insulin resistance are related to obesity and fitness in a diverse sample of 11–14 year olds: The HEALTHY Study by Jago, R, Drews, K L, Otvos, J D, Willi, S M, Buse, J B

“…Background: GlycA is a novel serum marker of systemic inflammation. There is no information on GlycA in pediatric populations, how it differs by gender or its…”
Get full text

Association of cholesteryl ester transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk : The Framingham study by ORDOVAS, J. M, CUPPLES, L. A, CORELLA, D, OTVOS, J. D, OSGOOD, D, MARTINEZ, A, LAHOZ, C, COLTELL, O, WILSON, P. W. F, SCHAEFER, E. J

“…Cholesteryl ester transfer protein (CETP) facilitates the exchange of triglycerides and cholesteryl esters between lipoprotein particles, a key step in reverse…”
Get full text

Acute and prolonged changes in lipoprotein profile in human volunteers treated with single ascending doses of MDCO-216 (apoA1-MILANO/POPC) by Kempen, H, Asztalos, B.F, Jeyarajah, E, Otvos, J, Gomaraschi, M, Calabresi, L, Kallend, D, Bobillier, A, Bellibas, S, Wijngaard, P

Get full text

Effects of a single infusion of synthetic HDL containing apoA-IMilano (MDCO-216) in healthy volunteers and stable coronary artery disease patients by Gomaraschi, M, Kempen, H, Simonelli, S, Calabresi, L, Moerland, M, Otvos, J, Jeyarajah, E, Kallend, D, Wijngaard, P

Get full text

Investigating dysfunctional-hdl in selected groups of patients at high risk of cardiovascular events (dys-hdl study) - Protocol and organization by Banach, M, Rysz, J, Rizzo, M, Otvos, J, Toth, P.P, Pencina, M.J, Mlynarski, W, Mikhailidis, D.P

Get full text

Incubation of MDCO216 with human serum potentiates ABCA1 mediated cholesterol efflux capacity and generates new prebeta-1 Hdl by Kempen, H, Schranz, D, Asztalos, B, Otvos, J, Jeyarajah, E, Drazul-Schrader, D, Collins, H, Adelman, S

Get full text

The prospective association between adiponectin and coronary artery disease among individuals with type 1 diabetes. The Pittsburgh Epidemiology of Diabetes Complications Study by COSTACOU, T, ZGIBOR, J. C, EVANS, R. W, OTVOS, J, LOPES-VIRELLA, M. F, TRACY, R. P, ORCHARD, T. J

“…Recent findings suggest the potential involvement of adiponectin in obesity, diabetes and cardiovascular disease. We assessed the prospective association…”
Get full text

Relation of Lipoprotein Subclasses as Measured by Proton Nuclear Magnetic Resonance Spectroscopy to Coronary Artery Disease by Freedman, David S, Otvos, James D, Jeyarajah, Elias J, Barboriak, Joseph J, Anderson, Alfred J, Walker, John A

“…Although each of the major lipoprotein fractions is composed of various subclasses that may differ in atherogenicity, the importance of this heterogeneity has…”
Get full text

Nuclear magnetic resonance-determined lipoprotein subclass profile in the DCCT/EDIC cohort: associations with carotid intima-media thickness by Lyons, T. J., Jenkins, A. J., Zheng, D., Klein, R. L., Otvos, J. D., Yu, Y., Lackland, D. T., McGee, D., McHenry, M. B., Lopes-Virella, M., Garvey, W. T.

“…Aims  To relate nuclear magnetic resonance lipoprotein subclass profiles (NMR‐LSP) and other lipoprotein‐related factors with carotid intima‐media thickness…”
Get full text

Lipoprotein subclass measurements by nuclear magnetic resonance spectroscopy improve the prediction of coronary artery disease in Type 1 diabetes. A prospective report from the Pittsburgh Epidemiology of Diabetes Complications Study by SOEDAMAH-MUTHU, S. S, CHANG, Y.-F, OTVOS, J, EVANS, R. W, ORCHARD, T. J

“…To examine whether nuclear magnetic resonance lipoprotein spectroscopy improves the prediction of coronary artery disease in patients with Type 1 diabetes,…”
Get full text

Three-dimensional solution structure of mouse [Cd7]-metallothionein-1 by homonuclear and heteronuclear NMR spectroscopy by ZANGGER, KLAUS, ÖZ, GÜLIN, OTVOS, JAMES D., ARMITAGE, IAN M.

“…Sequential 1H-NMR assignments of mouse [Cd7]-metallothionein-1 (MT1) have been carried out by standard homonuclear NMR methods and the use of an…”
Get full text

Endothelial Lipase Is a Major Genetic Determinant for High-Density Lipoprotein Concentration, Structure, and Metabolism by Ma, Ke, Cilingiroglu, Mehmet, Otvos, James D., Ballantyne, Christie M., Marian, Ali J., Chan, Lawrence

“…High-density lipoprotein (HDL) protects against atherosclerosis. Endothelial lipase (EL) has been postulated to be involved in lipoprotein, and possibly HDL,…”
Get full text

Use of human immunodeficiency virus-1 protease inhibitors is associated with atherogenic lipoprotein changes and endothelial dysfunction by STEIN, James H, KLEIN, Melissa A, BELLEHUMEUR, Jennifer L, MCBRIDE, Patrick E, WIEBE, Donald A, OTVOS, James D, SOSMAN, James M

“…Human immunodeficiency virus protease inhibitors (HIV PIs) are associated with hyperlipidemia, hyperglycemia, and obesity; however, it is not known whether…”
Get full text

Measurement of triglyceride‐rich lipoproteins by nuclear magnetic resonance spectroscopy by Otvos, James

“…Nuclear magnetic resonance (NMR) spectroscopy is being used to determine the concentrations of very low‐density lipoprotein (VLDL), low‐density lipoprotein…”
Get full text

Oxidative dimerization in metallothionein is a result of intermolecular disulphide bonds between cysteines in the alpha-domain by Zangger, K, Shen, G, Oz, G, Otvos, J D, Armitage, I M

“…Upon storage under aerobic conditions metallothioneins (MTs) form a new species, which is characterized by a molecular mass approximately twice the size of…”
Get full text

Association of the C−514T Polymorphism in the Hepatic Lipase Gene With Variations in Lipoprotein Subclass Profiles: The Framingham Offspring Study by Couture, Patrick, Otvos, James D, Cupples, L Adrienne, Lahoz, Carlos, Wilson, Peter W. F, Schaefer, Ernst J, Ordovas, Jose M

“…ABSTRACTHepatic lipase is involved in the metabolism of several lipoproteins and has a key role in reverse cholesterol transport. A common C-to-T substitution…”
Get full text

Development of a proton nuclear magnetic resonance spectroscopic method for determining plasma lipoprotein concentrations and subspecies distributions from a single, rapid measurement by Otvos, J D, Jeyarajah, E J, Bennett, D W, Krauss, R M

“…We are developing a method for quantifying plasma lipoproteins by proton nuclear magnetic resonance (NMR) spectroscopy that offers advantages over existing…”
Get more information