Search Results - "OTTANA, R"

Isoniazid-related copper(II) and nickel(II) complexes with antimycobacterial in vitro activity. Part 9 by BOTTARI, B, MACCARI, R, MONFORTE, F, OTTANA, R, ROTONDO, E, VIGORITA, M. G

“…Isonicotinoylhydrazones 1, obtained by the primary antituberculous agent Isoniazid, have been used as monoanionic ligands (L) to prepare copper(II) 2 and…”
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Design and synthesis of DNA-intercalating 9-fluoren-β- O-glycosides as potential IFN-inducers, and antiviral and cytostatic agents by Alcaro, S, Arena, A, Neri, S, Ottanà, R, Ortuso, F, Pavone, B, Vigorita, M.G

“…Novel 9-fluoren-β- O-glycosides, designed as DNA-intercalating agents in structural correlation with antiviral tilorone and anticancer anthracyclines, have…”
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Nickel(II) 2,6-diacetylpyridine bis(isonicotinoylhydrazonate) and bis(benzoylhydrazonate) complexes: structure and antimycobacterial evaluation. Part XI by Bottari, B., Maccari, R., Monforte, F., Ottanà, R., Vigorita, M.G., Bruno, G., Nicolò, F., Rotondo, A., Rotondo, E.

“…The reaction of 2,6-diacetylpyridine (dap) and isonicotinoyl- or benzoylhydrazide leads to bishydrazones H 2dapin ( 1a) and H 2dapb ( 1b), respectively. The…”
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Synthesis and aldose reductase inhibitory activity of 5-arylidene-2,4-thiazolidinediones by Bruno, G, Costantino, L, Curinga, C, Maccari, R, Monforte, F, Nicolò, F, Ottanà, R, Vigorita, M.G

“…Several (Z)-5-arylidene-2,4-thiazolidinediones were synthesized and tested as aldose reductase inhibitors (ARIs). The most active of the N-unsubstituted…”
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Antimycobacterial in vitro activity of cobalt(II) isonicotinoylhydrazone complexes. Part 10 by BOTTARI, B, MACCARI, R, MONFORTE, F, OTTANA, R, ROTONDO, E, VIGORITA, M. G

“…Octahedral cobalt(II) complexes of isonicotinoylhydrazones, which were obtained from the primary antituberculous agent isoniazid, have been synthesised and…”
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Synthesis and antiinflammatory, analgesic activity of 3,3′-(1,2-Ethanediyl)-bis[2-aryl-4-thiazolidinone] chiral compounds. Part 10 by Vigorita, M.G, Ottanà, R, Monforte, F, Maccari, R, Trovato, A, Monforte, M.T, Taviano, M.F

“…In this note, the synthesis and structure–activity relationships of a new series of 2 R,2′ R/2 S,2′ S and 2 R,2′S- meso…”
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UV–vis and FTIR-ATR characterization of 9-fluorenon-2-carboxyester/(2-hydroxypropyl)-β-cyclodextrin inclusion complex by Stancanelli, R., Ficarra, R., Cannavà, C., Guardo, M., Calabrò, M.L., Ficarra, P., Ottanà, R., Maccari, R., Crupi, V., Majolino, D., Venuti, V.

“…In this work, the usefulness of (2-hydroxypropyl)-β-cyclodextrin (HP-β-CyD) as a tool to form an inclusion complex with 9-fluorenonic derivative (AG11) has…”
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Identification of minor oxygen heterocyclic compounds of citrus essential oils by liquid chromatography-atmospheric pressure chemical ionisation mass spectrometry by Dugo, P, Mondello, L, Sebastiani, E, Ottana, R, Errante, G, Dugo, G

“…The oxygen heterocyclic compounds (coumarins, psoralens, and polymethoxylated flavones (PMFs)) present in citrus essential oils (lemon, mandarin, sweet orange,…”
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In vitro advanced antimycobacterial screening of isoniazid-related hydrazones, hydrazides and cyanoboranes: Part 14 by Maccari, Rosanna, Ottanà, Rosaria, Vigorita, Maria Gabriella

“…The in vitro antimycobacterial activities of some isoniazid derivatives are reported. As a part of an ongoing search for new isoniazid-related…”
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5-Arylidene-2-imino-4-thiazolidinones: Design and synthesis of novel anti-inflammatory agents by Ottanà, Rosaria, Maccari, Rosanna, Barreca, Maria Letizia, Bruno, Giuseppe, Rotondo, Archimede, Rossi, Antonietta, Chiricosta, Giuseppa, Di Paola, Rosanna, Sautebin, Lidia, Cuzzocrea, Salvatore, Vigorita, Maria Gabriella

“…[Display omitted] The synthesis and pharmacological activity of 5-arylidene-2-imino-4-thiazolidinones ( 3a– 8a) are described. All derivatives exhibited…”
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Chiral 3,3′-(1,2-Ethanediyl)-bis[2-(3,4-dimethoxyphenyl)-4-thiazolidinones] with anti-inflammatory activity. Part 11: Evaluation of COX-2 selectivity and modelling by Vigorita, M.G, Ottanà, R, Monforte, F, Maccari, R, Monforte, M.T, Trovato, A, Taviano, M.F, Miceli, N, De Luca, G, Alcaro, S, Ortuso, F

“…Anti-inflammatory/analgesic 3,3′-(1,2-ethanediyl)-bis[2-(3,4-dimethoxyphenyl)-4-thiazolidinones] 1, obtained as racemic mixtures ( a) and mesoforms ( b), have…”
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Configurational assignments of the diastereomers of 3,3′-(1,2-ethanediyl)bis[2-(3-fluorophenyl)-5-methyl-4-thiazolidinone] derivative with four stereogenic centers by Vigorita, Maria Gabriella, Ottaná, Rosaria, Monforte, Francesca, Previtera, Tindara, Maccari, Rosanna

“…Diastereomers of antiinflammatory/analgesic and antihistaminic 3,3′[(1,2‐ethanediyl)bis(2‐aryl‐4‐thiazo‐lidinone)] derivatives possessing two stereogenic…”
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In vitro antiproliferative activity against human colon cancer cell lines of representative 4-thiazolidinones. Part I by Ottanà, Rosaria, Carotti, Stefania, Maccari, Rosanna, Landini, Ida, Chiricosta, Giuseppa, Caciagli, Barbara, Vigorita, Maria Gabriella, Mini, Enrico

“…The characterization of two cyclooxygenase isoforms (COX), the rate-limiting enzyme for the synthesis of prostaglandins (PGs) from arachidonic acid, has…”
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Structure–activity relationships and molecular modelling of 5-arylidene-2,4-thiazolidinediones active as aldose reductase inhibitors by Maccari, Rosanna, Ottanà, Rosaria, Curinga, Carmela, Vigorita, Maria Gabriella, Rakowitz, Dietmar, Steindl, Theodora, Langer, Thierry

“…[Display omitted] The structure–activity relationships (SARs) of 5-arylidene-2,4-thiazolidinediones active as aldose reductase inhibitors (ARIs) were extended…”
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In vitro aldose reductase inhibitory activity of 5-benzyl-2,4-thiazolidinediones by Rakowitz, Dietmar, Maccari, Rosanna, Ottanà, Rosaria, Vigorita, Maria Gabriella

“…Several 5-benzyl-2,4-thiazolidinediones ( 5– 7) were synthesised and tested as in vitro aldose reductase (ALR2) inhibitors. Most of them, particularly…”
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3,3'-Bi(1,3-thiazolidin-4-one) system. VIII. 3,3'-(1,2-Ethanediyl) derivatives and corresponding 1,1'-disulfones: synthesis, stereochemistry and antiinflammatory activity by Vigorita, M G, Previtera, T, Ottanà, R, Grillone, I, Monforte, F, Monforte, M T, Trovato, A, Rossitto, A

“…To deeply investigate the influence of lipophilicity, phenyl substitution patterns and stereo-chemistry on pharmacological profiles of chiral…”
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Halogenated isoniazid derivatives as possible antimycobacterial and anti-HIV agents--III by Vigorita, M G, Ottanà, R, Zappalà, C, Maccari, R, Pizzimenti, F C, Gabbrielli, G

“…As part of a research directed to the synthesis of novel isoniazid derivatives with potential activity on mycobacteria and HIV virus, the…”
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2'-[1-(4-Fluorophenyl)ethyl]isonicotino-κN-hydrazide-Cyanoborane by Bruno, G., Maccari, R., Nicoló, F., Ottaná, R., Panzalorto, M., Scopelliti, R., Vigorita, M. G.

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Trifluoromethylcontaining sulfanilamides. I. Synthesis and in vitro antibacterial activity by Vigorita, M G, Ottanà, R, Bisignano, G

“…In a wider research directed to improve pharmacological profiles of known anti-infective agents by introducing fluorine or trifluoromethyl groups, some…”
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Halogenated isoniazid derivatives VI. Evaluation of anti-HSV-1 and anti-HIV-1 in vitro activities of fluorinated analogues by Arena, A, Capozza, A B, Maccari, R, Ottanà, R, Vigorita, M G

“…The synthesis and evaluation of antiviral in vitro activity are reported of some 2'-(1-arylethyl)isonicotinohydrazides (5a-d) and…”
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