Search Results - "OTSTOT, John"
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The SPANX Gene Family of Cancer/Testis-Specific Antigens: Rapid Evolution and Amplification in African Great Apes and Hominids
Published in Proceedings of the National Academy of Sciences - PNAS (02-03-2004)“…Human sperm protein associated with the nucleus on the X chromosome (SPANX) genes comprise a gene family with five known members (SPANX-A1, -A2, -B, -C, and…”
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Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27
Published in Genome research (01-11-2005)“…Genetic linkage studies indicate that germline variations in a gene or genes on chromosome Xq27-28 are implicated in prostate carcinogenesis. The linkage peak…”
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Identification of a novel region of homozygous deletion on chromosome 9p in squamous cell carcinoma of the lung : The location of a putative tumor suppressor gene
Published in Cancer research (Chicago, Ill.) (1997)“…Cytogenetic and molecular studies have implied the presence of tumor suppressor genes (TSGs) on chromosome 9p that are critical in the development of lung and…”
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Exclusion of the 750-kb genetically unstable region at Xq27 as a candidate locus for prostate malignancy in HPCX1-linked families
Published in Genes chromosomes & cancer (01-10-2012)“…Several linkage studies provided evidence for the presence of the hereditary prostate cancer locus, HPCX1, at Xq27‐q28. The strongest linkage peak of prostate…”
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Mutational analysis of SPANXGenes in families with X-linked prostate cancer
Published in The Prostate (01-06-2007)Get full text
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Mutational analysis of SPANX genes in families with X-Linked prostate cancer
Published in The Prostate (01-06-2007)“…BACKGROUND Previous genetic linkage studies identified a locus for susceptibility to prostate cancer called HPCX at Xq27. The candidate region contains two…”
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Segments missing from the draft human genome sequence can be isolated by transformation-associated recombination cloning in yeast
Published in EMBO reports (01-03-2003)“…The reported draft human genome sequence includes many contigs that are separated by gaps of unknown sequence. These gaps may be due to chromosomal regions…”
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