Search Results - "OTAKA, A"

Integrated dynamic bandwidth allocation for low buffer aggregated passive optical network systems by Ou, H., Sakai, Y., Ujikawa, H., Tsutsumi, T., Fujiwara, T., Kimura, Y., Sakamoto, T., Suzuki, H., Terada, J., Otaka, A.

“…The relentless increase in network capacity is making it important to reduce power consumption. In optical access network systems, the buffer size in layer-2…”
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Why Is Phosphonodifluoromethyl Phenylalanine a More Potent Inhibitory Moiety Than Phosphonomethyl Phenylalanine Toward Protein-Tyrosine Phosphatases by Chen, L., Wu, L., Otaka, A., Smyth, M.S., Roller, P.P., Burke, T.R., Denhertog, J., Zhang, Z.Y.

“…The phosphonodifluoromethyl phenylalanine (F2Pmp) is superior to phosphonomethyl phenylalanine (Pmp) as a non-hydrolyzable phosphotyrosine (pTyr) mimetic. The…”
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Heterodimer Formation between the Antimicrobial Peptides Magainin 2 and PGLa in Lipid Bilayers:  A Cross-Linking Study by Hara, Toshiaki, Mitani, Yasuyuki, Tanaka, Kyoko, Uematsu, Natsuko, Takakura, Asako, Tachi, Tomoya, Kodama, Hiroaki, Kondo, Michio, Mori, Harumi, Otaka, Akira, Nobutaka, Fujii, Matsuzaki, Katsumi

“…The antimicrobial peptides magainin 2 and PGLa, isolated from the skin of the African clawed frog Xenopus laevis, show marked synergism [Westerhoff, H. V.,…”
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Synthesis of fluorine-containing bioisosteres corresponding to phosphoamino acids and dipeptide units by Otaka, Akira, Mitsuyama, Etsuko, Watanabe, Junko, Watanabe, Hideaki, Fujii, Nobutaka

“…It has been shown that fluorinated analogues of naturally occurring biological active compounds including amino acids often exhibit unique physiological…”
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Structure-activity relationships of an anti-HIV peptide, T22 by Tamamura, H, Murakami, T, Masuda, M, Otaka, A, Takada, W, Ibuka, T, Nakashima, H, Waki, M, Matsumoto, A, Yamamoto, N

“…T22 ([Tyr5,12,Lys7]-polyphemusin II) has been shown to have a strong anti-human immunodeficiency virus (HIV) activity comparable to that of…”
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Assembly of synthetic laminin peptides into a triple-stranded coiled-coil structure by Nomizu, M, Otaka, A, Utani, A, Roller, P P, Yamada, Y

“…Laminin, a large multidomain glycoprotein specific to basement membranes, is a heterotrimer with alpha, beta, and gamma chains held together in an…”
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Multiplicity of virus-encoded helper T-cell epitopes expressed on FBL-3 tumor cells by IWASHIRO, M, KONDO, T, MIYAZAWA, M, ROBERTSON, M. N, CHESEBRO, B, KURIBAYASHI, K, SHIMIZU, T, YAMAGISHI, H, TAKAHASHI, K, MATSUBAYASHI, Y, MASUDA, T, OTAKA, A, FUJII, N, ISHIMOTO, A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Synthetic (Tyr 5,12,Lys 7)-Polyphemusin II Peptide (T22) Binds to the CD4 Cell Surface Molecule by Weeks, B.S., Nomizu, M., Otaka, A., Weston, C.A., Okusu, A., Tamamura, H., Yamamoto, N., Fujii, N.

“…The [Tyr 5,12, Lys 7]-polyphemusin II peptide (T22) inhibits HIV-1 replication in lymphocytes. The mechanism of T22 inhibition of HIV-1 replication may involve…”
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T140 analogs as CXCR4 antagonists identified as anti-metastatic agents in the treatment of breast cancer by Tamamura, Hirokazu, Hori, Akira, Kanzaki, Naoyuki, Hiramatsu, Kenichi, Mizumoto, Makiko, Nakashima, Hideki, Yamamoto, Naoki, Otaka, Akira, Fujii, Nobutaka

“…A chemokine receptor, CXCR4, and its endogenous ligand, stromal cell-derived factor-1 (SDF-1), have been recognized to be involved in the metastasis of several…”
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A New Practical Strategy for the Synthesis of Long-Chain Phosphopeptide by MIYOSHI, Kengo, OTAKA, AKira, KANEKO, Midori, TAMAMURA, Hirokazu, FUJII, Nobutaka

“…A new practical strategy has been developed for the synthesis of long-chain phosphopeptide. Both the 2-chlorobenzyloxycarbonyl (ClZ) group for Lys and methyl…”
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1H-NMR and Circular Dichroism Spectroscopic Studies on Changes in Secondary Structures of the Sodium Channel Inactivation Gate Peptides as Caused by the Pentapeptide KIFMK by Kuroda, Yoshihiro, Maeda, Yoshitaka, Miyamoto, Kazuhide, Tanaka, Kazufumi, Kanaori, Kenji, Otaka, Akira, Fujii, Nobutaka, Nakagawa, Terumichi

“…The pentapeptide KIFMK, which contains three clustered hydrophobic amino acid residues of isoleucine, phenylalanine, and methionine (IFM) in the sodium channel…”
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Cyclic peptide inhibitors of phosphatidylinositol 3-kinase p85 SH2 domain binding by Burke, Jr, T R, Nomizu, M, Otaka, A, Smyth, M S, Roller, P P, Case, R D, Wolf, G, Shoelson, S E

“…Cyclic hexameric peptides based on the amino acid sequence "Gly-Xxx-Val-Pro-Met-Leu", where Xxx is either phosphotyrosyl (pTyr) residue or a hydrolytically…”
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HIV protease inhibitor nelfinavir inhibits replication of SARS-associated coronavirus by Yamamoto, Norio, Yang, Rongge, Yoshinaka, Yoshiyuki, Amari, Shinji, Nakano, Tatsuya, Cinatl, Jindrich, Rabenau, Holger, Doerr, Hans Wilhelm, Hunsmann, Gerhard, Otaka, Akira, Tamamura, Hirokazu, Fujii, Nobutaka, Yamamoto, Naoki

“…A novel coronavirus has been identified as an etiological agent of severe acute respiratory syndrome (SARS). To rapidly identify anti-SARS drugs available for…”
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Cysteine-Derived S-Protected Oxazolidinones:  Potential Chemical Devices for the Preparation of Peptide Thioesters by Ohta, Yusuke, Itoh, Saori, Shigenaga, Akira, Shintaku, Saori, Fujii, Nobutaka, Otaka, Akira

“…An N − S acyl-transfer-mediated preparation of peptide thioesters using the S-protected oxazolidinone derived from cysteine has been developed and applied to…”
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Structural study of the sodium channel inactivation gate peptide including an isoleucine-phenylalanine-methionine motif and its analogous peptide (phenylalanine/glutamine) in trifluoroethanol solutions and SDS micelles by Kuroda, Y., Miyamoto, K., Matsumoto, M., Maeda, Y., Otaka, A., Fujii, N., Nakagawa, T., Kanaori, K.

“…In order to gain insight into the gating mechanisms of Na+ channels, in particular their inactivation mechanisms, we studied the structures of the Na+ channel…”
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Active Site Peptides with CXXC Motif on Map-Resin Can Mimic Protein Disulfide Isomerase Activity by Ookura, T., Kainuma, K., Kim, H.J., Otaka, A., Fujii, N., Kawamura, Y.

“…Two conserved Trp-Cys-Gly-His-Cys (WCGHC) sequences are assigned to act as catalytic sites for protein disulfide isomerase. Peptides containing the active site…”
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Unequivocal Synthesis of (Z)-Alkene and (E)-Fluoroalkene Dipeptide Isosteres To Probe Structural Requirements of the Peptide Transporter PEPT1 by Niida, Ayumu, Tomita, Kenji, Mizumoto, Makiko, Tanigaki, Hiroaki, Terada, Tomohiro, Oishi, Shinya, Otaka, Akira, Inui, Ken-ichi, Fujii, Nobutaka

“…Described is a novel synthetic route for dipeptide isosteres containing (Z)-alkene and (E)-fluoroalkene units as cis-amide bond equivalents via…”
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Identification of a CXCR4 antagonist, a T140 analog, as an anti-rheumatoid arthritis agent by Tamamura, Hirokazu, Fujisawa, Miho, Hiramatsu, Kenichi, Mizumoto, Makiko, Nakashima, Hideki, Yamamoto, Naoki, Otaka, Akira, Fujii, Nobutaka

“…Several recent papers support the involvement of an interaction between stromal cell-derived factor-1 (SDF-1/CXCL12) and its receptor, chemokine receptor…”
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Lymphocytes and promonocytes attach to the synthetic [Tyr5,12, Lys7]- polyphemusin II peptide by Weeks, B S, Nomizu, M, Otaka, A, Weston, C A, Okusu, A, Tamamura, H, Matsumoto, A, Yamamoto, N, Fujii, N

“…The [Tyr5,12,Lys7]-polyphemusin II peptide (T22) has been shown to inhibit HIV-1 replication in lymphocytes. The mechanism of T22 inhibition of HIV-1…”
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Molecular-Size Reduction of a Potent CXCR4-Chemokine Antagonist Using Orthogonal Combination of Conformation- and Sequence-Based Libraries by Fujii, Nobutaka, Oishi, Shinya, Hiramatsu, Kenichi, Araki, Takanobu, Ueda, Satoshi, Tamamura, Hirokazu, Otaka, Akira, Kusano, Shuichi, Terakubo, Shigemi, Nakashima, Hideki, Broach, James A., Trent, John O., Wang, Zi-xuan, Peiper, Stephen C.

“…Efficient downsizing of peptides: By combination of two orthogonal “conformation‐based” and “sequence‐based” libraries, the cyclic pentapeptide cyclo(‐L‐Nal…”
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