Search Results - "OTA, Toshio"

Event-Related Alpha-Band Power Changes During Self-reflection and Working Memory Tasks in Healthy Individuals by Matsuoka, Takahiro, Shimode, Takaki, Ota, Toshio, Matsuo, Koji

“…Dysfunctional attentional control is observed in patients with mental disorders. However, there is no established neurophysiological method to assess attention…”
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Direct generation of induced pluripotent stem cells from human nonmobilized blood by Kunisato, Atsushi, Wakatsuki, Mariko, Shinba, Haruna, Ota, Toshio, Ishida, Isao, Nagao, Kenji

“…The use of induced pluripotent stem cells (iPSCs) is an exciting frontier in the study and treatment of human diseases through the generation of specific cell…”
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Overexpression of chitinase 3-like 1/YKL-40 in lung-specific IL-18-transgenic mice, smokers and COPD by Sakazaki, Yuki, Hoshino, Tomoaki, Takei, Satoko, Sawada, Masanori, Oda, Hanako, Takenaka, Shin-ichi, Imaoka, Haruki, Matsunaga, Kazuko, Ota, Toshio, Abe, Yuzuru, Miki, Ichiro, Fujimoto, Kiminori, Kawayama, Tomotaka, Kato, Seiya, Aizawa, Hisamichi

“…We analyzed the lung mRNA expression profiles of a murine model of COPD developed using a lung-specific IL-18-transgenic mouse. In this transgenic mouse, the…”
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Chaotic use of depression-related medical terms: how should it be settled? by Ota, Toshio

“…Along with the marked increase of depressive patients, psychiatric terms related to depression have come to be exposed to many lay people in recent years. As a…”
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Preclinical and phase I clinical studies of KW-2450, a dual IGF-1R/IR tyrosine kinase inhibitor, in combination with lapatinib and letrozole by Umehara, Hiroshi, Maekawa, Yoshimi, Koizumi, Fumito, Shimizu, Makiko, Ota, Toshio, Fouad, Tamer M., Willey, Jie, Kaito, Hidekuni, Shiraishi, Norihiko, Nakashima, Daisuke, Akinaga, Shiro, Ueno, Naoto T.

“…Background: KW-2450 is an oral dual insulin-like growth factor-1 receptor/insulin receptor tyrosine kinase inhibitor. We investigated the in vitro and in vivo…”
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Erratum to: Brain structure differences among male schizophrenic patients with history of serious violent acts: an MRI voxel-based morphometric study by Kuroki, Noriomi, Kashiwagi, Hiroko, Ota, Miho, Ishikawa, Masanori, Kunugi, Hiroshi, Sato, Noriko, Hirabayashi, Naotsugu, Ota, Toshio

“…This article [1] has been updated to correct the image order. In the original article, Figs. 2 and 3 were interchanged. The figures are now in the correct…”
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RhoC and guanine nucleotide exchange factor Net1 in androgen-unresponsive mouse mammary carcinoma SC-4 cells and human prostate cancer after short-term endocrine therapy by Kawata, Hirotoshi, Shimada, Naoki, Kamiakito, Tomoko, Komatsu, Kenji, Morita, Tatsuo, Ota, Toshio, Obayashi, Masaya, Shitara, Kenya, Tanaka, Akira

“…BACKGROUND Endocrine resistance is a critical issue in managing patients with prostate cancer. This study is undertaken to search for a potential molecular…”
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The Molecular Characterization and Tissue Distribution of the Human Cysteinyl Leukotriene CysLT2 Receptor by Takasaki, Jun, Kamohara, Masazumi, Matsumoto, Mitsuyuki, Saito, Tetsu, Sugimoto, Toru, Ohishi, Takahide, Ishii, Hiroyuki, Ota, Toshio, Nishikawa, Tetsuo, Kawai, Yuri, Masuho, Yasuhiko, Isogai, Takao, Suzuki, Yutaka, Sugano, Sumio, Furuichi, Kiyoshi

“…Cysteinyl leukotrienes (CysLTs), slow-reacting substances of anaphylaxis, are lipid mediators known to possess potent proinflammatory action. Pharmacological…”
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Statistical Analysis of the 5′ Untranslated Region of Human mRNA Using “Oligo-Capped” cDNA Libraries by Suzuki, Yutaka, Ishihara, Daisuke, Sasaki, Masahide, Nakagawa, Haruhito, Hata, Hiroko, Tsunoda, Takeshi, Watanabe, Manabu, Komatsu, Takami, Ota, Toshio, Isogai, Takao, Suyama, Akira, Sugano, Sumio

“…We constructed 34 types of human “full-length enriched” and “5′-end enriched” cDNA libraries based on the “Oligo-Capping” method. We randomly picked and…”
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Transcriptome analysis of acetate metabolism in Corynebacterium glutamicum using a newly developed metabolic array by Hayashi, M. (Kyowa Hakko Kogyo Co. Ltd., Machida, Tokyo (Japan). Tokyo Research Lab.), Mizoguchi, H, Shiraishi, N, Obayashi, M, Nakagawa, S, Imai, J, Watanabe, S, Ota, T, Ikeda, M

“…Following the determination of the whole-genome sequence of Corynebacterium glutamicum, we have devel-oped a DNA array to extensively investigate gene…”
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Confusion in disease names between depression and depressive disorder by Ota, Toshio, Toyoshima, Ryoichi

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Seizures by Ota, Toshio

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Functional activation of Gαq/11 protein via α1‐adrenoceptor in rat cerebral cortical membranes by Odagaki, Yuji, Kinoshita, Masakazu, Ota, Toshio

“…Summary Although it is recognized that α1‐adrenoceptors are coupled to diverse intracellular signalling pathways, its primary transduction mechanisms are…”
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Functional activation of Gα q/11 protein via α 1 -adrenoceptor in rat cerebral cortical membranes by Odagaki, Yuji, Kinoshita, Masakazu, Ota, Toshio

“…Although it is recognized that α -adrenoceptors are coupled to diverse intracellular signalling pathways, its primary transduction mechanisms are evoked by…”
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Mood profile evaluation by families, young physicians and experienced psychiatrists in an actual clinical practice setting by OTA, TOSHIO, SASAKI, YUKI, YAMAUCHI, TOSHIO

“…The purpose of this study was to explore differences in mood profile evaluation between raters with different backgrounds. Special emphasis was placed on…”
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Dopamine-induced functional activation of Gαq mediated by dopamine D1-like receptor in rat cerebral cortical membranes by Odagaki, Yuji, Kinoshita, Masakazu, Ota, Toshio

“…Although multiple roles of dopamine through D 1 -like (D 1 and D 5 ) and D 2 -like (D 2 , D 3 , and D 4 ) receptors are initiated primarily through stimulation…”
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Comparative analysis of pharmacological properties of xanomeline and N-desmethylclozapine in rat brain membranes by Odagaki, Yuji, Kinoshita, Masakazu, Ota, Toshio

“…Background: 3(3-Hexyloxy-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine (xanomeline) and N-desmethylclozapine are of special interest as promising…”
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Dopamine-induced functional activation of Gα q mediated by dopamine D 1 -like receptor in rat cerebral cortical membranes by Odagaki, Yuji, Kinoshita, Masakazu, Ota, Toshio

“…Although multiple roles of dopamine through D -like (D and D ) and D -like (D , D , and D ) receptors are initiated primarily through stimulation or inhibition…”
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Visual presentation of psychiatric clinical decision-making by "graphic assessment sheet for diagnoses and treatments" by Ota, Toshio, Yoshida, Sumiko, Tsunashima, Sousuke, Totsuka, Takao, Watanabe, Takafumi, Toyoshima, Ryoichi

“…Psychiatrists often have to treat patients even when the clinical information is insufficient to make a definite diagnosis. This is the case especially when we…”
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Chimeric Mice With Humanized Livers Demonstrate Human-Specific Hepatotoxicity Caused by a Therapeutic Antibody Against TRAIL-Receptor 2/Death Receptor 5 by Nihira, Kaito, Nan-ya, Ken-ichiro, Kakuni, Masakazu, Ono, Yoko, Yoshikawa, Yukitaka, Ota, Toshio, Hiura, Masanori, Yoshinari, Kouichi

“…Abstract The activation of tumor necrosis factor (TNF)-related apoptosis-inducing ligand receptor 2 (TRAIL-R2)/death receptor 5 (DR5) induces apoptosis in…”
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