Search Results - "OSUGI, JUN"

The clinical significance of tertiary lymphoid structure and its relationship with peripheral blood characteristics in patients with surgically resected non-small cell lung cancer: a single-center, retrospective study by Fukuhara, Mitsuro, Muto, Satoshi, Inomata, Sho, Yamaguchi, Hikaru, Mine, Hayato, Takagi, Hironori, Ozaki, Yuki, Watanabe, Masayuki, Inoue, Takuya, Yamaura, Takumi, Okabe, Naoyuki, Matsumura, Yuki, Hasegawa, Takeo, Osugi, Jun, Hoshino, Mika, Higuchi, Mitsunori, Shio, Yutaka, Suzuki, Hiroyuki

“…Introduction The presence of tertiary lymphoid structure (TLS) in tumor tissues has been reported to be a factor associated with a good prognosis in several…”
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CTLA-4 Expression in Tumor-infiltrating Lymphocytes Is Irrelevant to PD-L1 Expression in NSCLC by Muto, Satoshi, Inomata, Sho, Yamaguchi, Hikaru, Mine, Hayato, Takagi, Hironori, Ozaki, Yuki, Watanabe, Masayuki, Inoue, Takuya, Yamaura, Takumi, Fukuhara, Mitsuro, Okabe, Naoyuki, Matsumura, Yuki, Hasegawa, Takeo, Osugi, Jun, Hoshino, Mika, Higuchi, Mitsunori, Shio, Yutaka, Suzuki, Hiroyuki

“…Treatments containing ipilimumab have shown a good outcome in patients with non-small cell lung cancer (NSCLC) regardless of the PD-L1 tumor proportion score…”
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Wnt/β-Catenin Signaling and Resistance to Immune Checkpoint Inhibitors: From Non-Small-Cell Lung Cancer to Other Cancers by Muto, Satoshi, Enta, Akio, Maruya, Yoshiyuki, Inomata, Sho, Yamaguchi, Hikaru, Mine, Hayato, Takagi, Hironori, Ozaki, Yuki, Watanabe, Masayuki, Inoue, Takuya, Yamaura, Takumi, Fukuhara, Mitsuro, Okabe, Naoyuki, Matsumura, Yuki, Hasegawa, Takeo, Osugi, Jun, Hoshino, Mika, Higuchi, Mitsunori, Shio, Yutaka, Hamada, Kazuyuki, Suzuki, Hiroyuki

“…Lung cancer is the leading cause of cancer-related deaths worldwide. The standard of care for advanced non-small-cell lung cancer (NSCLC) without driver-gene…”
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Genetic alterations in epidermal growth factor receptor‑tyrosine kinase inhibitor‑na ve non‑small cell lung carcinoma by Yamaura, Takumi, Muto, Satoshi, Mine, Hayato, Takagi, Hironori, Watanabe, Masayuki, Ozaki, Yuki, Inoue, Takuya, Fukuhara, Mitsuro, Okabe, Naoyuki, Matsumura, Yuki, Hasegawa, Takeo, Osugi, Jun, Hoshino, Mika, Higuchi, Mitsunori, Shio, Yutaka, Suzuki, Hiroyuki

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The efficacy of the Kampo medicine rikkunshito for chemotherapy-induced anorexia (RICH trial): study protocol for a randomized controlled trial by Inoue, Takuya, Takagi, Hironori, Owada, Yuki, Watanabe, Yuzuru, Yamaura, Takumi, Fukuhara, Mitsuro, Muto, Satoshi, Okabe, Naoyuki, Matsumura, Yuki, Hasegawa, Takeo, Osugi, Jun, Hoshino, Mika, Higuchi, Mitsunori, Shio, Yutaka, Yokouchi, Hiroshi, Kanazawa, Kenya, Ohbuchi, Katsuya, Fukushima, Takahisa, Munakata, Mitsuru, Suzuki, Hiroyuki

“…Cisplatin is a key drug in lung cancer therapy. However, cisplatin is also well known to induce gastrointestinal disorders, such as chemotherapy-induced nausea…”
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Prognostic Impact of Hypoxia-Inducible miRNA-210 in Patients with Lung Adenocarcinoma by Okabe, Naoyuki, Matsumura, Yuki, Yonechi, Athushi, Hoshino, Mika, Higuchi, Mitsunori, Shio, Yutaka, Suzuki, Hiroyuki, Gotoh, Mitsukazu, Muto, Satoshi, Fukuhara, Mitsuro, Yamaura, Takumi, Watanabe, Yuzuru, Inoue, Takuya, Owada, Yuki, Kimura, Yuka, Osugi, Jun, Hasegawa, Takeo

“…Objective. The aim of this study was to investigate the prognostic value of MicroRNA-210 (miR-210) expression in patients with non-small-cell lung cancer…”
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Prognostic Impact of FDG-PET in Surgically Treated Pathological Stage I Lung Adenocarcinoma by Higuchi, Mitsunori, Hasegawa, Takeo, Osugi, Jun, Suzuki, Hiroyuki, Gotoh, Mitsukazu

“…Purpose: This retrospective study evaluated whether the maximum standardized uptake value (SUVmax) on 18F-deoxyglucose (FDG)-positron emission tomography (PET)…”
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Comparison of surgical outcomes after pneumonectomy and pulmonary function-preserving surgery for non-small cell lung cancer by Higuchi, Mitsunori, Takagi, Hironori, Ozaki, Yuki, Inoue, Takuya, Watanabe, Yuzuru, Yamaura, Takumi, Fukuhara, Mitsuro, Muto, Satoshi, Okabe, Naoyuki, Matsumura, Yuki, Hasegawa, Takeo, Osugi, Jun, Hoshino, Mika, Shio, Yutaka, Suzuki, Hiroyuki

“…Background: According to previous reports, lobectomy with bronchoplasty or angioplasty is a more feasible surgery than pneumonectomy for central-type non-small…”
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Successful Management of Crizotinib-Induced Neutropenia in a Patient with Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer: A Case Report by Osugi, Jun, Owada, Yuki, Yamaura, Takumi, Muto, Satoshi, Okabe, Naoyuki, Matsumura, Yuki, Higuchi, Mitsunori, Suzuki, Hiroyuki, Gotoh, Mitsukazu

“…Crizotinib, the first clinically available inhibitor of anaplastic lymphoma kinase (ALK) gene rearrangement, is generally well tolerated. In contrast,…”
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Prognostic impact of the combination of glucose transporter 1 and ATP citrate lyase in node-negative patients with non-small lung cancer by Osugi, Jun, Yamaura, Takumi, Muto, Satoshi, Okabe, Naoyuki, Matsumura, Yuki, Hoshino, Mika, Higuchi, Mitunori, Suzuki, Hiroyuki, Gotoh, Mitsukazu

“…Highlights • Co-expression of GLUT1 plus ACLY in lung cancer (NSCLC) patients was studied. • GLUT1 plus ACLY status indicated worse overall survival than GLUT1…”
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Uniportal Thoracoscopic Bisegmentectomy of Medial and Posterior Basal Segment (S7+S10) by Cong, Yue, Nagano, Masaaki, Fujishima, Kosuke, Osugi, Jun, Fujiu, Koichi, Sato, Masaaki

“…When a tumor is located in the medial (S7) or posterior (S10) basal segment, it is sometimes necessary to perform a bisegmentectomy of S7 and S10 (S7+S10) to…”
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Prognostic impact of the high-sensitivity modified Glasgow prognostic score in patients with resectable non-small cell lung cancer by Osugi, Jun, Muto, Satoshi, Matsumura, Yuki, Higuchi, Mitsunori, Suzuki, Hiroyuki, Gotoh, Mitsukazu

“…Objective: The present study compared the prognostic value of the Glasgow prognostic score (GPS), modified GPS (mGPS), high-sensitivity mGPS (HS-mGPS),…”
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Quantitative T-cell repertoire analysis of peripheral blood mononuclear cells from lung cancer patients following long-term cancer peptide vaccination by Takeda, Kazuyoshi, Kitaura, Kazutaka, Suzuki, Ryuji, Owada, Yuki, Muto, Satoshi, Okabe, Naoyuki, Hasegawa, Takeo, Osugi, Jun, Hoshino, Mika, Tsunoda, Takuya, Okumura, Ko, Suzuki, Hiroyuki

“…Therapeutic cancer peptide vaccination is an immunotherapy designed to elicit cytotoxic T-lymphocyte (CTL) responses in patients. A number of therapeutic…”
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Clinical significance of expanded Foxp3+ Helios− regulatory T cells in patients with non-small cell lung cancer by MUTO, SATOSHI, OWADA, YUKI, INOUE, TAKUYA, WATANABE, YUZURU, YAMAURA, TAKUMI, FUKUHARA, MITSURO, OKABE, NAOYUKI, MATSUMURA, YUKI, HASEGAWA, TAKEO, OSUGI, JUN, HOSHINO, MIKA, HIGUCHI, MITSUNORI, SUZUKI, HIROYUKI, GOTOH, MITSUKAZU

“…The functions of different regulatory T cell (Treg) types in cancer progression are unclear. Recently, expression of the transcription factor Helios was…”
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Delta-like 1 homolog (DLK1) as a possible therapeutic target and its application to radioimmunotherapy using 125I-labelled anti-DLK1 antibody in lung cancer models (HOT1801 and FIGHT004) by Takagi, Hironori, Zhao, Songji, Muto, Satoshi, Yokouchi, Hiroshi, Nishihara, Hiroshi, Harada, Toshiyuki, Yamaguchi, Hikaru, Mine, Hayato, Watanabe, Masayuki, Ozaki, Yuki, Inoue, Takuya, Yamaura, Takumi, Fukuhara, Mitsuro, Okabe, Naoyuki, Matsumura, Yuki, Hasegawa, Takeo, Osugi, Jun, Hoshino, Mika, Higuchi, Mitsunori, Shio, Yutaka, Kanno, Ryuzo, Aoki, Miho, Tan, Chengbo, Shimoyama, Saki, Yamazaki, Shigeo, Kikuchi, Hajime, Sakakibara-Konishi, Jun, Oizumi, Satoshi, Harada, Masao, Akie, Kenji, Sugaya, Fumiko, Fujita, Yuka, Takamura, Kei, Kojima, Tetsuya, Honjo, Osamu, Minami, Yoshinori, Nishimura, Masaharu, Dosaka-Akita, Hirotoshi, Nakamura, Koji, Inano, Akihiro, Isobe, Hiroshi, Suzuki, Hiroyuki

“…•DLK1 is a member of the Notch ligand family such as delta-like 3 (DLL3).•DLK1 is expressed in a subset of both small-cell lung cancer (SCLC) and…”
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Multiple therapeutic peptide vaccines consisting of combined novel cancer testis antigens and anti-angiogenic peptides for patients with non-small cell lung cancer by Suzuki, Hiroyuki, Fukuhara, Mitsuro, Yamaura, Takumi, Mutoh, Satoshi, Okabe, Naoyuki, Yaginuma, Hiroshi, Hasegawa, Takeo, Yonechi, Atsushi, Osugi, Jun, Hoshino, Mika, Kimura, Takashi, Higuchi, Mitsunori, Shio, Yutaka, Ise, Kazuya, Takeda, Kazuyoshi, Gotoh, Mitsukazu

“…Vaccine treatment using multiple peptides derived from multiple proteins is considered to be a promising option for cancer immune therapy, but scientific…”
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Tumor β-catenin expression is associated with immune evasion in non-small cell lung cancer with high tumor mutation burden by Muto, Satoshi, Ozaki, Yuki, Yamaguchi, Hikaru, Mine, Hayato, Takagi, Hironori, Watanabe, Masayuki, Inoue, Takuya, Yamaura, Takumi, Fukuhara, Mitsuro, Okabe, Naoyuki, Matsumura, Yuki, Hasegawa, Takeo, Osugi, Jun, Hoshino, Mika, Higuchi, Mitsunori, Shio, Yutaka, Nanamiya, Hideaki, Imai, Jun-Ichi, Isogai, Takao, Watanabe, Shinya, Suzuki, Hiroyuki

“…β-catenin expression by tumor cells suppressed dendritic cell recruitment to the tumor microenvironment in a melanoma model, resulting in fewer…”
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Serum Nitric Oxide as a Predictive Biomarker for Bevacizumab in Non-small Cell Lung Cancer Patients by Muto, Satoshi, Takagi, Hironori, Owada, Yuki, Inoue, Takuya, Watanabe, Yuzuru, Yamaura, Takumi, Fukuhara, Mitsuro, Okabe, Naoyuki, Matsumura, Yuki, Hasegawa, Takeo, Osugi, Jun, Hoshino, Mika, Higuchi, Mitsunori, Shio, Yutaka, Suzuki, Hiroyuki

“…Reportedly, hypertension tends to be associated with response to bevacizumab therapy, because bevacizumab suppresses vascular nitric oxide production. In this…”
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Epidermal growth factor receptor gene mutation as risk factor for recurrence in patients with surgically resected lung adenocarcinoma: a matched-pair analysis by Matsumura, Yuki, Owada, Yuki, Yamaura, Takumi, Muto, Satoshi, Osugi, Jun, Hoshino, Mika, Higuchi, Mitsunori, Ohira, Tetsuya, Suzuki, Hiroyuki, Gotoh, Mitsukazu

“…OBJECTIVES Epidermal growth factor receptor (EGFR) mutation is a robust prognostic factor in patients with lung adenocarcinoma (ADC). However, the role of EGFR…”
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Clinical and therapeutic impact of family with sequence similarity 83, member B in EGFR gene wild type-lung adenocarcinoma by Yamaura, Takumi, Okabe, Naoyuki, Takagi, Hironori, Owada, Yuki, Inoue, Takuya, Watanabe, Yuzuru, Fukuhara, Mitsuro, Muto, Satoshi, Matsumura, Yuki, Hasegawa, Takeo, Hoshino, Mika, Osugi, Jun, Shio, Yutaka, Ezaki, Junji, Watanabe, Shinya, Suzuki, Hiroyuki

“…Abstract only e23136 Background: We have reported the usefulness of Family with sequence similarity 83, member B (FAM83B) as a novel biomarker for diagnosis…”
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