Search Results - "OSTROW, L"
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PML-IRIS in patients with HIV infection : Clinical manifestations and treatment with steroids
Published in Neurology (28-04-2009)“…Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection that develops in immunosuppressed patients with HIV infection. Paradoxically,…”
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2
Global alterations to the choroid plexus blood-CSF barrier in amyotrophic lateral sclerosis
Published in Acta neuropathologica communications (26-06-2020)“…Abstract The choroid plexus (CP) is a highly vascularized structure located in the ventricles that forms the blood-CSF barrier (BCSFB) and separates the blood…”
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3
Cancer evolution is associated with pervasive positive selection on globally expressed genes
Published in PLoS genetics (01-03-2014)“…Cancer is an evolutionary process in which cells acquire new transformative, proliferative and metastatic capabilities. A full understanding of cancer requires…”
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4
The varicella zoster virus vasculopathies : Clinical, CSF, imaging, and virologic features
Published in Neurology (11-03-2008)“…Varicella zoster virus (VZV) vasculopathy produces stroke secondary to viral infection of cerebral arteries. Not all patients have rash before cerebral…”
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5
An Epigenetic Marker Panel for Detection of Lung Cancer Using Cell-Free Serum DNA
Published in Clinical cancer research (01-07-2011)“…We investigated the feasibility of detecting aberrant DNA methylation of some novel and known genes in the serum of lung cancer patients. To determine the…”
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Coordinated activation of candidate proto-oncogenes and cancer testes antigens via promoter demethylation in head and neck cancer and lung cancer
Published in PloS one (23-03-2009)“…Epigenetic alterations have been implicated in the pathogenesis of solid tumors, however, proto-oncogenes activated by promoter demethylation have been…”
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7
KIF1A and EDNRB are differentially methylated in primary HNSCC and salivary rinses
Published in International journal of cancer (15-11-2010)“…Silencing of tumor suppressor genes plays a vital role in head and neck carcinogenesis. In this study, we aimed to evaluate to the utility of aberrant promoter…”
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Correlation between BRAF mutation and promoter methylation of TIMP3, RARβ2 and RASSF1A in thyroid cancer
Published in Epigenetics (01-07-2012)“…Our aim was to comprehensively analyze promoter hypermethylation of a panel of novel and known methylation markers for thyroid neoplasms and to establish their…”
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A survey of methylated candidate tumor suppressor genes in nasopharyngeal carcinoma
Published in International journal of cancer (15-03-2011)“…Nasopharyngeal carcinoma (NPC) is a rare malignancy with unique genetic, viral and environmental characteristic that distinguishes it from other head and neck…”
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10
Relation of Contraceptive and Reproductive History to Ovarian Cancer Risk in Carriers and Noncarriers of BRCA1 Gene Mutations
Published in American journal of epidemiology (01-10-2004)“…In the general population, ovarian cancer risk is inversely associated with oral contraceptive use, tubal ligation, and childbearing. Among carriers of BRCA1…”
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Prevalence of BRCA1 Mutation Carriers among U.S. Non-Hispanic Whites
Published in Cancer epidemiology, biomarkers & prevention (01-12-2004)“…Data from several countries indicate that 1% to 2% of Ashkenazi Jews carry a pathogenic ancestral mutation of the tumor suppressor gene BRCA1 . However, the…”
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12
Hickam's dictum and the rare convergence of antisynthetase syndrome and hemoglobin SC disease
Published in QJM : An International Journal of Medicine (01-09-2015)Get full text
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13
Immunohistochemistry of affected tissue may guide cGVHD treatment decisions
Published in Bone marrow transplantation (Basingstoke) (01-05-2012)“…Chronic graft-vs-host disease (cGVHD) myositis is a rare complication of hematopoietic SCT, for which the pathogenesis and optimal therapy are unclear. We…”
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14
ssDNA-Binding Protein 2 Is Frequently Hypermethylated and Suppresses Cell Growth in Human Prostate Cancer
Published in Clinical cancer research (15-06-2008)“…Purpose: Prostate cancer is a major cause of cancer death among men and the development of new biomarkers is important to augment current detection approaches…”
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15
Breast and Ovarian Cancer in Relatives of Cancer Patients, with and without BRCA Mutations
Published in Cancer epidemiology, biomarkers & prevention (01-02-2006)“…Background: First-degree relatives of patients with breast or ovarian cancer have increased risks for these cancers. Little is known about how their risks vary…”
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16
Informatics Solutions for Driving an Effective and Efficient Radiology Practice
Published in Radiographics (01-10-2018)“…Radiologists are facing increasing workplace pressures that can lead to decreased job satisfaction and burnout. The increasing complexity and volumes of cases…”
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P.174 TRIM32 related muscular dystrophy mimicking inflammatory myopathy: Clinical and histopathological features in two siblings
Published in Neuromuscular disorders : NMD (01-10-2022)Get full text
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18
The Somatic Nature of Cancer Allows It to Affect Highly Constrained Genes
Published in Genome biology and evolution (01-05-2016)“…Cancer is special among genetic disorders in two major ways: first, cancer is a disease of the most basic of cellular functions, such as cell proliferation,…”
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Variation in KRAS driver substitution distributions between tumor types is determined by both mutation and natural selection
Published in Scientific reports (23-02-2016)“…Different tumor types vary greatly in their distribution of driver substitutions. Here, we analyzed how mutation and natural selection contribute to…”
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20
Mechanosensation and endothelin in astrocytes—hypothetical roles in CNS pathophysiology
Published in Brain Research Reviews (01-06-2005)“…Endothelin (ET) is a potent autocrine mitogen produced by reactive and neoplastic astrocytes. ET has been implicated in the induction of astrocyte…”
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