Search Results - "OSTERMANN, Georg"
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Non-random distribution of mutations in the PHEX gene, and under-detected missense mutations at non-conserved residues
Published in European journal of human genetics : EJHG (01-07-1999)“…Thirty newly detected mutations in the PHEX gene are reported, and pooled with all the previously published mutations. The spectrum of mutations displayed 16%…”
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JAM-1 is a ligand of the β2 integrin LFA-1 involved in transendothelial migration of leukocytes
Published in Nature immunology (01-02-2002)Get full text
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JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes
Published in Nature immunology (01-02-2002)“…Inflammatory recruitment of leukocytes is governed by dynamic interactions between integrins and endothelial immunoglobulin superfamily (IgSF) proteins. We…”
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The Functional Interaction of the β2 Integrin Lymphocyte Function-Associated Antigen-1 with Junctional Adhesion Molecule-A Is Mediated by the I Domain
Published in The Journal of immunology (1950) (15-11-2004)“…Binding of the β2 integrin LFA-1 (αLβ2) to junctional adhesion molecule-A (JAM-A) has been shown to enhance leukocyte adhesion and transendothelial migration…”
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Induction of cancer cell apoptosis by α‐tocopheryl succinate: molecular pathways and structural requirements
Published in The FASEB journal (01-02-2001)“…ABSTRACT The vitamin E analog α‐tocopheryl succinate (α‐TOS) can induce apoptosis. We show that the proapoptotic activity of α‐TOS in hematopoietic and cancer…”
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Involvement of JAM-A in Mononuclear Cell Recruitment on Inflamed or Atherosclerotic Endothelium: Inhibition by Soluble JAM-A
Published in Arteriosclerosis, thrombosis, and vascular biology (01-04-2005)“…OBJECTIVE—The junctional adhesion molecule (JAM)-A on endothelium contributes to the inflammatory recruitment of mononuclear cells involving engagement of its…”
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Alpha-tocopheryl succinate, an agent with in vivo anti-tumour activity, induces apoptosis by causing lysosomal instability
Published in Biochemical journal (15-03-2002)“…Certain vitamin E analogues, such as alpha-tocopheryl succinate (alpha-TOS), exhibit in vivo anti-tumour activity and, in vitro, induce apoptosis of cultured…”
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Cytohesin-1 is a dynamic regulator of distinct LFA-1 functions in leukocyte arrest and transmigration triggered by chemokines
Published in Current biology (11-12-2001)“…Cytohesin-1 is a regulatory interaction partner of the β2 integrin αLβ2 (LFA-1) and a guanine exchange factor (GEF) for ADP ribosylation factor (ARF)-GTPases…”
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The functional interaction of the beta 2 integrin lymphocyte function-associated antigen-1 with junctional adhesion molecule-A is mediated by the I domain
Published in The Journal of immunology (1950) (15-11-2004)“…Binding of the beta(2) integrin LFA-1 (alpha(L)beta(2)) to junctional adhesion molecule-A (JAM-A) has been shown to enhance leukocyte adhesion and…”
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The Functional Interaction of the beta sub(2) Integrin Lymphocyte Function- Associated Antigen-1 with Junctional Adhesion Molecule-A Is Mediated by the I Domain
Published in The Journal of immunology (1950) (15-11-2004)“…Binding of the beta sub(2) integrin LFA-1 ( alpha sub(L)beta sub(2)) to junctional adhesion molecule-A (JAM-A) has been shown to enhance leukocyte adhesion and…”
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Dual Role of H-Ras in Regulation of Lymphocyte Function Antigen-1 Activity by Stromal Cell-derived Factor-1α: Implications for Leukocyte Transmigration
Published in Molecular biology of the cell (01-10-2001)“…We investigated the role of H-Ras in chemokine-induced integrin regulation in leukocytes. Stimulation of Jurkat T cells with the CXC chemokine stromal…”
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JAM-1 is a ligand of the [beta]2 integrin LFA-1 involved in transendothelial migration of leukocytes
Published in Nature immunology (01-02-2002)“…Inflammatory recruitment of leukocytes is governed by dynamic interactions between integrins and endothelial immunoglobulin superfamily (IgSF) proteins. We…”
Get full text
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13
JAM-1 is a ligand of the β 2 integrin LFA-1 involved in transendothelial migration of leukocytes
Published in Nature immunology (01-02-2002)Get full text
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14
α-Tocopheryl succinate, an agent with in vivo anti-tumour activity, induces apoptosis by causing lysosomal instability
Published in Biochemical journal (15-03-2002)“…Certain vitamin E analogues, such as α-tocopheryl succinate (α-TOS), exhibit in vivo anti-tumour activity and, in vitro, induce apoptosis of cultured tumour…”
Get full text
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Dual role of H-Ras in regulation of lymphocyte function antigen-1 activity by stromal cell-derived factor-1alpha: implications for leukocyte transmigration
Published in Molecular biology of the cell (01-10-2001)“…We investigated the role of H-Ras in chemokine-induced integrin regulation in leukocytes. Stimulation of Jurkat T cells with the CXC chemokine stromal…”
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Induction of cancer cell apoptosis by a-tocopheryl succinate: Molecular pathways and structural requirements
Published in The FASEB journal (01-02-2001)“…The vitamin E analog a-tocopheryl succinate (a-TOS) can induce apoptosis. We show that the proapoptotic activity of a-TOS in hematopoietic and cancer cell…”
Get full text
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