Search Results - "OSTER, Laurence"
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Risk management strategies in the postmarketing period : Safety experience with the US and european bosentan surveillance programmes
Published in Drug safety (01-01-2005)“…In view of the shortcomings of the current system for postmarketing drug surveillance that is based on voluntary spontaneous adverse drug reaction (ADR)…”
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Effects of Renin-Angiotensin Blockade on Sympathetic Reactivity and beta-Adrenergic Pathway in the Spontaneously Hypertensive Rat
Published in Hypertension (Dallas, Tex. 1979) (01-08-1997)“…As interactions between the renin-angiotensin and sympathetic nervous systems have been suggested in the pathogenesis of hypertension, we wanted to investigate…”
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Effects of chronic treatment with losartan and enalaprilat on [ 3H]-Norepinephrine release from isolated atria of wistar-kyoto and spontaneously hypertensive rats
Published in American journal of hypertension (1996)“…The present study was designed to evaluate the effect of chronic treatment with losartan, an AT 1 angiotensin II receptor antagonist, and enalaprilat, an…”
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Altered protein kinase C regulation of phosphoinsitide-coupled receptors in deoxycorticosterone acetate-salt hypertensive rats
Published in Hypertension (Dallas, Tex. 1979) (01-06-1994)Get full text
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Role of NO and angiotensin II in the early development of endothelial functions impairment and cardiac hypertrophy in deoxycorticosterone acetate-salt hypertension
Published in Canadian journal of physiology and pharmacology (01-06-1998)“…This study was designed to investigate the effects of chronic inhibition of NO synthesis as well as chronic angiotensin receptor blockade with losartan in the…”
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Altered Protein Kinase C Regulation of Phosphoinositide-Coupled Receptors in Deoxycorticosterone Acetate-Salt Hypertensive Rats
Published in Hypertension (Dallas, Tex. 1979) (01-06-1994)“…This study examined the contribution of phosphatidylinositol metabolism and the efficacy of protein kinase C-mediated desensitization in the exaggerated…”
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The vasorelaxant effect of deuterium oxide is secondary to calcium-induced liberation of nitric oxide by endothelial cells
Published in Journal of hypertension (01-10-1993)“…To test the hypothesis that deuterium oxide (D2O) might induce endothelium-dependent and nitric oxide-mediated vasodilation by altering intracellular calcium…”
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Norepinephrine and serotonin increase the vasoconstrictor response of the perfused rat tail artery to changes in cytosolic Ca2
Published in European journal of pharmacology (25-04-1990)“…Vasoconstriction and changes in cytosolic free Ca2+ concentrations (fura 2 with dual wavelength excitation) were measured simultaneously in the perfused tail…”
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Vascular calcium overload produced by administration of vitamin D3 and nicotine in rats. Changes in tissue calcium levels, blood pressure, and pressor responses to electrical stimulation or norepinephrine in vivo
Published in Journal of cardiovascular pharmacology (01-08-1990)“…Increased calcium content of cardiovascular tissues is a phenomenon common to natural aging and various pathological conditions such as hypertension and…”
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In vitro vasoconstriction induced by calcium in renovascular hypertensive or old rats
Published in Life sciences (1973) (1990)“…We studied the changes in calcium-induced vasoconstriction in isolated tail arteries from young (2 months) and old (12 months) normotensive, and young…”
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