Search Results - "OSENDE, J"

Thrombus formation on atherosclerotic plaques : Pathogenesis and clinical consequences by RAUCH, Ursula, OSENDE, Julio I, FUSTER, Valentin, BADIMON, Juan J, FAYAD, Zahi, CHESEBRO, James H

“…To describe the characteristics of thrombus formation on atherosclerotic plaques, the clinical expression of atherothrombosis in vascular disease, and some of…”
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Statins and cardiovascular diseases: the multiple effects of lipid-lowering therapy by statins by Rauch, U., Osende, J.I., Chesebro, J.H., Fuster, V., Vorchheimer, D.A., Harris, K., Harris, P., Sandler, D.A., Fallon, J.T., Jayaraman, S., Badimon, J.J.

“…Cholesterol lowering involving different therapies improves the clinical outcome of patients. To define the underlying pathomechanism, we studied whether…”
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Antithrombotic effects of S 18886, a novel orally active thromboxane A2 receptor antagonist by Osende, J. I., Shimbo, D., Fuster, V., Dubar, M., Badimon, J. J.

“…Platelet activation and thrombus formation play a critical role in the onset of acute coronary syndromes. Thromboxane A2 (TxA2) is among the different chemical…”
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Acute antithrombotic effects of ximelagatran, an oral direct thrombin inhibitor, and r‐hirudin in a human ex vivo model of arterial thrombosis by Sarich, T. C., Osende, J. I., Eriksson, U. G., Fager, G. B., Eriksson‐Lepkowska, M., Ohlsson, L., Carlsson, S., Wåhlander, K., Gustafsson, D., Badimon, J. J.

“…Background: Thrombin plays a major role in thrombus formation through activation of platelets and conversion of fibrinogen to fibrin. Objectives: To…”
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Proteomic approach in the search of new cardiovascular biomarkers by Gallego-Delgado, Julio, Lazaro, Alberto, Osende, Julio J., Barderas, Maria M., Blanco-Colio, Luis L., Duran, Maria Carmen, Martin-Ventura, Jose J., Vivanco, Fernando, Egido, Jesus

“…Proteomic approach in the search of new cardiovascular biomarkers With the increasing incidence of cardiovascular diseases worldwide, specifically…”
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Blood thrombogenicity in type 2 diabetes mellitus patients is associated with glycemic control by Osende, Julio I, Badimon, Juan Jose, Fuster, Valentin, Herson, Perry, Rabito, Phil, Vidhun, Ramapriya, Zaman, Azfar, Rodriguez, Oswaldo J, Lev, Eli I, Rauch, Ursula, Heflt, Gerard, Fallon, John T, Crandall, Jill P

“…OBJECTIVES This study was designed to determine whether blood thrombogenicity is related to chronic glycemic control in type 2 diabetes mellitus (T2DM)…”
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Increased thrombus formation relates to ambient blood glucose and leukocyte count in diabetes mellitus type 2 by Rauch, Ursula, Crandall, Jill, Osende, Julio I, Fallon, John T, Chesebro, James H, Fuster, Valentin, Badimon, Juan J

“…The blood thrombogenicity assessed by ex vivo thrombus formation under defined rheologic conditions was higher in patients with type 2 diabetes than in…”
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Atherosclerotic aortic component quantification by noninvasive magnetic resonance imaging: an in vivo study in rabbits by Helft, Gérard, Worthley, Stephen G, Fuster, Valentin, Zaman, Azfar G, Schechter, Clyde, Osende, Julio I, Rodriguez, Oswaldo J, Fayad, Zahi A, Fallon, John T, Badimon, Juan J

“…OBJECTIVES We sought to demonstrate the ability that noninvasive in vivo magnetic resonance imaging (MRI) has to quantify the different components within…”
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Acute Antithrombotic Effect of a Front-Loaded Regimen of Clopidogrel in Patients With Atherosclerosis on Aspirin by Helft, Gérard, Osende, Julio I, Worthley, Stephen G, Zaman, Azfar G, Rodriguez, Oswaldo J, Lev, Eli I, Farkouh, Michael E, Fuster, Valentin, Badimon, Juan J, Chesebro, James H

“…There is a need for a rapid antithrombotic effect after the administration of antiplatelet drugs in the setting of acute coronary syndromes and percutaneous…”
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High resolution ex vivo magnetic resonance imaging of in situ coronary and aortic atherosclerotic plaque in a porcine model by Worthley, Stephen G, Helft, Gérard, Fuster, Valentin, Fayad, Zahi A, Fallon, John T, Osende, Julio I, Roqué, Mercè, Shinnar, Meir, Zaman, Azfar G, Rodriguez, Oswaldo J, Verhallen, Peter, Badimon, Juan J

“…Atherosclerotic plaque composition is central to the pathogenesis of plaque disruption and acute thrombosis. Thus, there is a need for accurate imaging and…”
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Effect of Clopidogrel Added to Aspirin in Patients with Atrial Fibrillation by Connolly, Stuart J, Pogue, Janice, Hart, Robert G, Hohnloser, Stefan H, Pfeffer, Marc, Chrolavicius, Susan, Yusuf, Salim

“…A randomized trial enrolled 7554 patients with atrial fibrillation who were at increased risk of stroke but not candidates for vitamin K antagonists…”
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Testing platelet activation with a shear-dependent platelet function test versus aggregation-based tests: Relevance for monitoring long-term glycoprotein IIb/IIIa inhibition by OSENDE, Julio I, FUSTER, Valentin, LEV, Eli I, SHIMBO, Daichi, RAUCH, Ursula, MARMUR, Jonathan D, RICHARD, Merwin, VARON, David, BADIMON, Juan Jose

“…Tests developed to monitor glycoprotein (GP) IIb/IIIa blockade do not properly reflect platelet function in vivo and need a baseline (pretreatment) value…”
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Troponin T Levels and Abciximab Therapy in Unstable Angina by Lev, Eli I, Osende, Julio I, Zaman, Azfar G, Hamm, Christian W, Heeschen, Christopher

“…To the Editor: The accuracy of measurements of troponin T and creatine kinase MB fraction (CK-MB) is central to the results of the c7E3 Fab Antiplatelet…”
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Usefulness of carotid and femoral plaque burden quantification by 3-dimensional vascular ultrasound for cardiovascular risk assessment in the cardiovascular disease prevention unit by Ruiz-Cabello Subiela, J, Martinez-Sepulveda, T, Medina, J, Varona, J F, Zorita, B, Fuertes, B, Pastor, A, Osende, J, Palomo, J, Castellano, J M, Parra Jimenez, F J, Fernandez-Friera, L, Lopez-Melgar, B

“…Abstract Introduction Subclinical atherosclerosis improves cardiovascular risk assessment and is considered a risk modifier in individuals at…”
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In Vivo Dynamic Real-Time Monitoring and Quantification of Platelet-Thrombus Formation: Use of a Local Isotope Detector by Zaman, Azfar G, Osende, Julio I, Chesebro, James H, Fuster, Valentin, Padurean, Adrian, Gallo, Richard, Worthley, Stephen G, Helft, Gerard, Rodriguez, Oswaldo X, Fallon, John T, Badimon, Juan J

“…ABSTRACTCurrent methods for monitoring thrombosis and thrombus growth are invasive and provide only single–time-point data. Animal models rely mainly on flow…”
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Statins to prevent cardiovascular events in hypertensive patients. The ASCOT-LLA study by Osende, Julio I., Ruiz-Ortega, Marta, Blanco-Colio, Luis Miguel, Egido, Jesus

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Nisoldipine and Myocardial Infarction by Osende, J I

“…To the Editor: Estacio et al. (March 5 issue) 1 report an increased incidence of fatal and nonfatal myocardial infarction in patients with hypertension and…”
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Role of risk factors in the modulation of tissue factor activity and blood thrombogenicity by SAMBOLA, Antonia, OSENDE, Julio, HATHCOCK, James, DEGEN, Michael, NEMERSON, Yale, FUSTER, Valentin, CRANDALL, Jill, BADIMON, Juan Jose

“…Several studies suggest a role for an increased circulating pool of tissue factor (TF) in atherothrombotic diseases. Furthermore, certain cardiovascular risk…”
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Artery dissection and arterial thrombus aging: the role of noninvasive magnetic resonance imaging by Corti, R, Osende, J I, Fuster, V, Fayad, Z A, Fallon, J T, Badimon, J J

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Administration of abciximab to patients receiving tirofiban or eptifibatide: effect on platelet function by Lev, Eli I, Osende, Julio I, Richard, Merwin F, Robbins, Jonathan A, Delfin, Jenny A, Rodriguez, Oswaldo, Sharma, Samin K, Jayasundera, Tim, Badimon, Juan J, Marmur, Jonathan D

“…OBJECTIVES The goal of this study was to evaluate platelet function and to preliminarily assess the clinical safety of sequential treatment with tirofiban or…”
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