Search Results - "OSELIN, Kersti"

Intensity of end-of-life health care and mortality after systemic anti-cancer treatment in patients with advanced lung cancer by Oselin, Kersti, Pisarev, Heti, Ilau, Keit, Kiivet, Raul-Allan

“…We aimed to study the mortality and intensity of health care in patients with advanced lung cancer who received systemic anti-cancer treatment (SACT) compared…”
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Health Care Resource Use at End of Life in Patients with Advanced Lung Cancer by Oselin, Kersti, Pisarev, Heti, Ilau, Keit, Kiivet, Raul-Allan

“…We aimed to study differences in the use of health care resources in relation to time before death in patients with advanced lung cancer who either received…”
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Unmet needs in EGFR exon 20 insertion mutations in Central and Eastern Europe: reimbursement, diagnostic procedures, and treatment availability by Hochmair, Maximilian J, Unk, Mojca, Spasic, Jelena, Cerić, Timur, Konsoulova, Assia, Dediu, Mircea, Bogos, Krisztina, Hegmane, Alinta, Oselin, Kersti, Stojiljkovic, Marko, Roblek, Tina, Jakopovic, Marko

“…Lung cancer remains the leading cause of cancer-related deaths in Europe, with non-small cell lung cancer (NSCLC) accounting for approximately 85% of cases…”
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Short versus Long Infusion of Meropenem in Very-Low-Birth-Weight Neonates by PADARI, Helgi, METSVAHT, Tuuli, KÖRGVEE, Lenne-Triin, GERMOVSEK, Eva, ILMOJA, Mari-Liis, KIPPER, Karin, HERODES, Koit, STANDING, Joseph F, OSELIN, Kersti, LUTSAR, Irja

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EORTC-SPECTA Arcagen study, comprehensive genomic profiling and treatment adaptation of rare thoracic cancers by Tagliamento, Marco, Morfouace, Marie, Loizides, Charalambos, Oliveira, Julio, Greillier, Laurent, Raimbourg, Judith, Toffart, Anne-Claire, Chatellier, Thierry, Cloarec, Nicolas, Sullivan, Ivana, Brasiuniene, Birute, Duruisseaux, Michael, Oselin, Kersti, Robert, Marie-Sophie, Fernandes, Carolina, Poncin, Arnaud, Blay, Jean-Yves, Besse, Benjamin, Girard, Nicolas

“…Arcagen (NCT02834884) is a European prospective study aiming at defining the molecular landscape of rare cancers for treatment guidance. We present data from…”
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Trends in opioid prescribing in Estonia (2011‐2017) by Uusküla, Anneli, Raag, Mait, Kurvits, Katrin, Laius, Ott, Uusküla, Maia, Oselin, Kersti

“…Our objective was to examine the trends and variation in opioid prescribing in Estonia from 2011 to 2017. This retrospective cross‐sectional study is based on…”
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Inhibition of Human Thiopurine S-Methyltransferase by Various Nonsteroidal Anti-inflammatory Drugs in Vitro: A Mechanism for Possible Drug Interactions by OSELIN, Kersti, ANIER, Kaili

“…Thiopurine S -methyltransferase (TPMT) is a biotransformation phase II enzyme responsible for the metabolic inactivation of thiopurine drugs. The present study…”
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Pharmacokinetics of Penicillin G in Very-Low-Birth-Weight Neonates by METSVAHT, Tuuli, OSELIN, Kersti, ILMOJA, Mari-Liis, ANIER, Kaili, LUTSAR, Irja

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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MDR1 polymorphisms G2677T in exon 21 and C3435T in exon 26 fail to affect rhodamine 123 efflux in peripheral blood lymphocytes by Oselin, Kersti, Gerloff, Thomas, Mrozikiewicz, Przemyslaw M., Pähkla, Rein, Roots, Ivar

“…P‐glycoprotein (Pgp) is a member of the ABC‐transporter family, and in humans, is encoded by the MDR1 gene. Recently, several single‐nucleotide polymorphisms…”
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Determination of thiopurine S-methyltransferase (TPMT) activity by comparing various normalization factors: Reference values for Estonian population using HPLC-UV assay by Oselin, Kersti, Anier, Kaili, Tamm, Riin, Kallassalu, Kristi, Mäeorg, Uno

“…Thiopurine S-methyltransferase (TPMT; EC 2.1.1.67) is the key enzyme in the metabolism of thiopurine drugs. Determination of TPMT activity has been used for…”
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Pembrolizumab versus placebo as adjuvant therapy for completely resected stage IB–IIIA non-small-cell lung cancer (PEARLS/KEYNOTE-091): an interim analysis of a randomised, triple-blind, phase 3 trial by O’Brien, Mary, Paz-Ares, Luis, Marreaud, Sandrine, Dafni, Urania, Oselin, Kersti, Havel, Libor, Esteban, Emilio, Isla, Dolores, Martinez-Marti, Alex, Faehling, Martin, Tsuboi, Masahiro, Lee, Jong-Seok, Nakagawa, Kazuhiko, Yang, Jing, Samkari, Ayman, Keller, Steven M, Mauer, Murielle, Jha, Nitish, Stahel, Rolf, Besse, Benjamin, Peters, Solange

“…Pembrolizumab is a standard-of-care for advanced non-small-cell lung cancer (NSCLC). We assessed pembrolizumab as adjuvant therapy for completely resected…”
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Quantitative determination of the human MRP1 and MRP2 mRNA expression in FACS-sorted peripheral blood CD4+, CD8+, CD19+, and CD56+cells by Oselin, Kersti, Mrozikiewicz, Przemyslaw M., Pähkla, Rein, Roots, Ivar

“…: Objectives: ATP‐binding cassette (ABC) transporters extrude a wide variety of endogenous and exogenous compounds. In cancer cells, they are known to confer…”
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Patterns of survival and surgical treatment in lung cancer patients in Estonia by histologic type and stage, 1996-2016 by Innos, Kaire, Oselin, Kersti, Laisaar, Tanel, Aareleid, Tiiu

“…Lung cancer (LC) remains the most frequent cause of cancer death worldwide. We aimed to examine long-term trends in LC survival in Estonia by age, gender,…”
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Pre- and post-operative lung cancer recurrence prediction following curative surgery: A retrospective study using European radiomics and clinical data by Valter, Ann, Kordemets, Tanel, Gasimova, Aydan, Waterfield Price, Noah, Freitag, Lutz, Vachani, Anil, Carbone, David Paul, Oselin, Kersti

“…8066 Background: Accurately estimating the risk of lung cancer recurrence is vital for making informed treatment choices, both before surgery, such as the…”
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Lung Cancer in Estonia by Laisaar, Tanel, Innos, Kaire, Jaal, Jana, Oselin, Kersti, Sarana, Bruno, Vanakesa, Tõnu, Laisaar, Kaja-Triin

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Ampicillin Pharmacokinetics During First Week of Life in Preterm and Term Neonates by Padari, Helgi, Soeorg, Hiie, Tasa, Tõnis, Metsvaht, Tuuli, Kipper, Karin, Herodes, Koit, Oselin, Kersti, Hallik, Maarja, Ilmoja, Mari-Liis, Lutsar, Irja

“…Ampicillin is 1 of the most commonly used antibiotics for treatment of early onset sepsis, but its pharmacokinetics (PK) is poorly characterized. We aimed to…”
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An International Registry Study of Early-Stage NSCLC treatment variations (LUCAEUROPE) in Europe and the USA highlighting variations by Baum, Philip, Cardoso, Rafael, Lenzi, Jacopo, Damhuis, Ronald A.M., Verhagen, Ad F.T.M., De Gendt, Cindy, Peacock, Hanna, De Leyn, Paul, Christensen, Niels L., Innos, Kaire, Oselin, Kersti, Zadnik, Vesna, Zagarv, Tina, Brenner, Hermann, Winter, Hauke

“…Harmonized European NSCLC incidence, treatment approach, and survival based on national tumor registries are unclear. Surgery has the potential to cure NSCLC…”
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Pharmacokinetics of oral spironolactone in infants up to 2 years of age by Lass, Jana, Leroux, Stephanie, Kõrgvee, Lenne-Triin, Varendi, Heili, Kipper, Karin, Takkis, Kalev, Aro, Rudolf, Metsvaht, Tuuli, Oselin, Kersti, Pfister, Marc, Soeorg, Hiie, van den Anker, Johannes, Lutsar, Irja

“…Purpose Spironolactone is a potassium sparing diuretic used for decades. Until now, pharmacokinetic (PK) studies of spironolactone have not been conducted in…”
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Pembrolizumab vs placebo for early-stage non‒small-cell lung cancer after resection and adjuvant therapy: Subgroup analysis of patients who received adjuvant chemotherapy in the phase 3 PEARLS/KEYNOTE-091 study by Oselin, Kersti, Shim, Byoung Yong, Okada, Morihito, Bryl, Maciej, Bonanno, Laura, Demirag, Guzin, Colantonio, Ida, Kimmich, Martin, Janzic, Urska, Vansteenkiste, Johan F., Bernabe Caro, Reyes, Scherz, Amina, Curioni-Fontecedro, Alessandra, Früh, Martin, Wollner, Mira, Yang, Jing, Shariati, Nazly, Marreaud, Sandrine, Peters, Solange, O'Brien, Mary ER

“…8520 Background: In the randomized, triple-blind, phase 3 PEARLS/KEYNOTE-091 study (NCT02504372), at the second interim analysis, pembrolizumab (pembro)…”
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Ampicillin Pharmacokinetics During First Week of Life in Preterm and Term Neonates by Padari, Helgi, Soeorg, Hiie, Tasa, Tõnis, Metsvaht, Tuuli, Kipper, Karin, Herodes, Koit, Oselin, Kersti, Hallik, Maarja, Ilmoja, Mari-Liis, Lutsar, Irja

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