Search Results - "ORZECHOWSKI, A"
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Crossroads of cytokine signaling--the chase to stop muscle cachexia
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01-12-2008)“…There is no universal approach to stop muscle cachexia in a number of life-threatening diseases. Accordingly, it is uncertain why the body mass is so critical…”
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Lipid rafts mediate epigallocatechin-3-gallate- and green tea extract-dependent viability of human colon adenocarcinoma COLO 205 cells; clusterin affects lipid rafts-associated signaling pathways
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01-08-2011)“…Epigallocatechin-3-gallate (EGCG) is an important bioactive constituent of green tea extract (GTE) that was widely believed to reduce proliferation of many…”
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Molecular basis of sodium butyrate-dependent proapoptotic activity in cancer cells
Published in Advances in medical sciences (2007)“…This review outlines the molecular events that accompany the antitumor action of sodium butyrate (NaBt). Butyrate, a low-molecular weight four-carbon chain…”
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Possible implications of redox-sensitive tumour cell transformation; lessons from cell culture studies
Published in Polish journal of veterinary sciences (2007)“…It is generally accepted that chronic inflammatory disease, either local or generalized, is associated with higher incidence of cancer. Since inflammation is…”
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Sodium butyrate-dependent sensitization of human colon adenocarcinoma COLO 205 cells to TNF-alpha-induced apoptosis
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01-08-2007)“…COLO 205 colon adenocarcinoma cells are highly resistant to extrinsic apoptosis induced by immunomodulatory cytokines. One of the antiapoptotic mechanisms is…”
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Justification for antioxidant preconditioning (or how to protect insulin-mediated actions under oxidative stress)
Published in Journal of biosciences (01-02-2003)“…Insulin resistance is characterized by impaired glucose utilization in the peripheral tissues, accelerated muscle protein degradation, impaired antioxidant…”
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Cholesterol level determines viability and mitogenicity, but it does not affect sodium butyrate-dependent sensitization of Colo 205 cells to TNF-α-induced apoptosis
Published in Oncology reports (01-02-2011)“…Transient treatment of human adenocarcinoma COLO 205 cells with lipit raft (LR) modulators (MßCD, NY, IMP) was followed by the challenge with metabolic…”
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Bisindolylmaleimides in anti-cancer therapy - more than PKC inhibitors
Published in Advances in medical sciences (2008)“…Bisindolylmaleimide derivatives were originally described as protein kinase C inhibitors. However, several studies have shown that bisindolylmaleimides target…”
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Overview how adenocarcinoma cancer cells avoid immune- and chemotherapy-induced apoptosis
Published in Advances in medical sciences (2006)“…This review describes some aspects of uncontrolled tumor growth and development. In the past, it has been shown that colon adenocarcinomas use several tactics…”
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Marine extinction risk shaped by trait–environment interactions over 500 million years
Published in Global change biology (01-10-2015)“…Perhaps the most pressing issue in predicting biotic responses to present and future global change is understanding how environmental factors shape the…”
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Expression of apoptosis-related proteins in mammary gland of goat
Published in Small ruminant research (01-06-2001)“…The expression of apoptosis-related proteins: TGF-β1 (auto/paracrine inducer) and its receptor (TGF-βRIII), Bax (promoter), Bcl-2 (inhibitor) and CPP-32…”
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Eliciting user preferences through a guided design personalization process
Published in Knowledge-based systems (01-04-2007)“…In building industry, sound methods are needed to determine the design options that respond to the requirements of the potential house buyers. A new method is…”
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Excess of glucocorticoids impairs whole-body antioxidant status in young rats. relation to the effect of dexamethasone in soleus muscle and spleen
Published in Hormone and metabolic research (01-05-2000)“…The action of glucocorticoids in high doses is catabolic, but not much is known about the accompanying effects on antioxidative capacity of the entire body…”
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In vitro metabolism of opioid tetrapeptide agonists in various tissues and subcellular fractions from rats
Published in Peptides (New York, N.Y. : 1980) (01-04-2001)“…The metabolism of three μ-selective opioid tetrapeptide agonists, Tyr- d-Arg-Phe-Nva-NH 2 (TArPN), Tyr- d-Arg-Phe-Phe-NH 2 (TArPP), and Tyr- d-Ala-Phe-Phe-NH 2…”
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High conservation of both phase I and II drug-metabolizing activities in cryopreserved rat liver slices
Published in Xenobiotica (01-09-2000)“…1. Xenobiotic-metabolizing enzymes, including both cytochrome P450 and phase IIconjugating systems, have been characterized in rat liver slices cryopreserved…”
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Dexamethasone-mediated regulation of death and differentiation of muscle cells. Is hydrogen peroxide involved in the process?
Published in Reproduction, nutrition, development (01-05-2002)“…The hypothetical involvement of H2O2 in dexamethasone-mediated regulation of muscle cell differentiation and elimination was studied. Rat L6 myoblasts and…”
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Apoptosis and Bcl-2 protein changes in L1210 leukaemic cells exposed to oxidative stress
Published in Apoptosis (London) (1997)“…The aim of this study was to explore the dose- and time-dependent effects of hydrophilic peroxyl radical initiator 2,2'azobis(2amidinopropane)dihydrochloride…”
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Investigations of the In-vitro Metabolism of Three Opioid Tetrapeptides by Pancreatic and Intestinal Enzymes
Published in Journal of pharmacy and pharmacology (01-07-2000)“…The metabolism of three opioid tetrapeptides, Tyr‐D‐Arg‐Phe‐Nva‐NH2, Tyr‐D‐Arg‐Phe‐Phe‐NH2 and Tyr‐D‐Ala‐Phe‐Phe‐NH2, was investigated in the presence of pure…”
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Phase II Metabolism of Benzene
Published in Environmental health perspectives (01-12-1996)Get full text
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