Search Results - "ORTIZ, Luis A"

Role of metabolic reprogramming in pro-inflammatory cytokine secretion from LPS or silica-activated macrophages by Marrocco, Antonella, Ortiz, Luis A.

“…In the lungs, macrophages constitute the first line of defense against pathogens and foreign bodies and play a fundamental role in maintaining tissue…”
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Electronic Relaxation Pathways in Heavy-Atom-Free Photosensitizers Absorbing Near-Infrared Radiation and Exhibiting High Yields of Singlet Oxygen Generation by Ortiz-Rodríguez, Luis A, Hoehn, Sean J, Loredo, Axel, Wang, Lushun, Xiao, Han, Crespo-Hernández, Carlos E

“…Heavy-atom-free photosensitizers (HAF-PSs) based on thionation of carbonyl groups of readily accessible organic compounds are rapidly emerging as a versatile…”
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Thionated organic compounds as emerging heavy-atom-free photodynamic therapy agents by Ortiz-Rodríguez, Luis A, Crespo-Hernández, Carlos E

“…This minireview focuses on recent progress in developing heavy-atom-free photosensitizers based on the thionation of nucleic acid derivatives and other…”
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Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs by Phinney, Donald G., Di Giuseppe, Michelangelo, Njah, Joel, Sala, Ernest, Shiva, Sruti, St Croix, Claudette M., Stolz, Donna B., Watkins, Simon C., Di, Y. Peter, Leikauf, George D., Kolls, Jay, Riches, David W. H., Deiuliis, Giuseppe, Kaminski, Naftali, Boregowda, Siddaraju V., McKenna, David H., Ortiz, Luis A.

“…Mesenchymal stem cells (MSCs) and macrophages are fundamental components of the stem cell niche and function coordinately to regulate haematopoietic stem cell…”
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Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications by Witwer, Kenneth W., Van Balkom, Bas W.M., Bruno, Stefania, Choo, Andre, Dominici, Massimo, Gimona, Mario, Hill, Andrew F., De Kleijn, Dominique, Koh, Mickey, Lai, Ruenn Chai, Mitsialis, S. Alex, Ortiz, Luis A., Rohde, Eva, Asada, Takashi, Toh, Wei Seong, Weiss, Daniel J., Zheng, Lei, Giebel, Bernd, Lim, Sai Kiang

“…Small extracellular vesicles (sEVs) from mesenchymal stromal/stem cells (MSCs) are transiting rapidly towards clinical applications. However, discrepancies and…”
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Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury by Ortiz, Luis A, DuTreil, Maria, Fattman, Cheryl, Pandey, Amitabh C, Torres, German, Go, Kristina, Phinney, Donald G

“…Mesenchymal stem cells (MSCs) have been exploited as cellular vectors to treat a wide array of diseases but the mechanisms responsible for their therapeutic…”
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Electronic relaxation mechanism of 9‐methyl‐2,6‐diaminopurine and 2,6‐diaminopurine‐2′‐deoxyribose in solution by Ortiz‐Rodríguez, Luis A., Caldero‐Rodríguez, Naishka E., Seth, Sourav Kanti, Díaz‐González, Karitza, Crespo‐Hernández, Carlos E.

“…Prolonged ultraviolet exposure results in the formation of cyclobutane pyrimidine dimers (CPDs) in RNA. Consequently, prebiotic photolesion repair mechanisms…”
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Insecticidal activity of essential oils from American native plants against Aedes aegypti (Diptera: Culicidae): an introduction to their possible mechanism of action by Duque, Jonny E., Urbina, Diana L., Vesga, Luis C., Ortiz-Rodríguez, Luis A., Vanegas, Thomas S., Stashenko, Elena E., Mendez-Sanchez, Stelia C.

“…Searching for new bioactive molecules to design insecticides is a complex process since pesticides should be highly selective, active against the vector, and…”
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Intramolecular Charge Transfer in the Azathioprine Prodrug Quenches Intersystem Crossing to the Reactive Triplet State in 6‐Mercaptopurine by Ortiz‐Rodríguez, Luis A., Ortiz‐Zayas, Glesmarie, Pollum, Marvin, Hoehn, Sean J., Jockusch, Steffen, Crespo‐Hernández, Carlos E.

“…The thiopurine prodrugs 6‐mercaptopurine and azathioprine are among the world’s essential medications for acute lymphoblastic leukemia, immunosuppression and…”
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The Triplet State of 6-thio-2′-deoxyguanosine: Intrinsic Properties and Reactivity Toward Molecular Oxygen by Pollum, Marvin, Ortiz-Rodríguez, Luis A., Jockusch, Steffen, Crespo-Hernández, Carlos E.

“…Thiopurine prodrugs are currently among the leading treatment options for leukemia, immunosuppression, and arthritis. Patients undergoing long‐term thiopurine…”
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Detection of the thietane precursor in the UVA formation of the DNA 6-4 photoadduct by Ortiz-Rodríguez, Luis A., Reichardt, Christian, Hoehn, Sean J., Jockusch, Steffen, Crespo-Hernández, Carlos E.

“…Notwithstanding the central biological role of the (6-4) photoadduct in the induction of skin cancer by sunlight, crucial mechanistic details about its…”
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On the Photostability of Cyanuric Acid and Its Candidature as a Prebiotic Nucleobase by Ortiz-Rodríguez, Luis A, Hoehn, Sean J, Crespo-Hernández, Carlos E

“…Cyanuric acid is a triazine derivative that has been identified from reactions performed under prebiotic conditions and has been proposed as a prospective…”
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Cell therapy trials for lung diseases: progress and cautions by Weiss, Daniel J, Ortiz, Luis A

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Mesenchymal Stem Cell Engraftment in Lung Is Enhanced in Response to Bleomycin Exposure and Ameliorates Its Fibrotic Effects by Ortiz, Luis A., Gambelli, Frederica, McBride, Christine, Gaupp, Dina, Baddoo, Melody, Kaminski, Naftali, Phinney, Donald G.

“…Previously we described a reliable method based on immunodepletion for isolating mesenchymal stem cells (MSCs) from murine bone marrow and showed that, after…”
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The BR-body proteome contains a complex network of protein-protein and protein-RNA interactions by Nandana, Vidhyadhar, Rathnayaka-Mudiyanselage, Imalka W., Muthunayake, Nisansala S., Hatami, Ali, Mousseau, C. Bruce, Ortiz-Rodríguez, Luis A., Vaishnav, Jamuna, Collins, Michael, Gega, Alisa, Mallikaarachchi, Kaveendya S., Yassine, Hadi, Ghosh, Aishwarya, Biteen, Julie S., Zhu, Yingxi, Champion, Matthew M., Childers, W. Seth, Schrader, Jared M.

“…Bacterial ribonucleoprotein bodies (BR-bodies) are non-membrane-bound structures that facilitate mRNA decay by concentrating mRNA substrates with RNase E and…”
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A Clinical Indications Prediction Scale Based on TWIST1 for Human Mesenchymal Stem Cells by Boregowda, Siddaraju V., Krishnappa, Veena, Haga, Christopher L., Ortiz, Luis A., Phinney, Donald G.

“…In addition to their stem/progenitor properties, mesenchymal stem cells (MSCs) also exhibit potent effector (angiogenic, antiinflammatory, immuno-modulatory)…”
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Interfacial 2D Montmorillonite Nanocoatings Enable Sandwiched Polymer Nanocomposites to Exhibit Ultrahigh Capacitive Energy Storage Performance at Elevated Temperatures by Wang, Yifei, Li, Zongze, Moran, Thomas J., Ortiz, Luis A., Wu, Chao, Konstantinou, Antigoni C., Nguyen, Hiep, Zhou, Jierui, Huo, Jindong, Davis‐Amendola, Kerry, Zhou, Peinan, Huey, Bryan D., Cao, Yang

“…Polymer dielectrics are essential for advanced electrical and electronic power systems due to their ultrafast charge–discharge rate. However, a long‐standing…”
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Combination of enteral and parenteral nutrition in the acute phase of critical illness: An updated systematic review and meta‐analysis by Hill, Aileen, Heyland, Daren K., Ortiz Reyes, Luis A., Laaf, Elena, Wendt, Sebastian, Elke, Gunnar, Stoppe, Christian

“…Background Uncertainty remains about the best route and timing of medical nutrition therapy in the acute phase of critical illness. Early combined enteral…”
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Mesenchymal Stem Cells from COPD Patients Are Capable of Restoring Elastase-Induced Emphysema in a Murine Experimental Model by Río, Carlos, Jahn, Andreas K, Martin-Medina, Aina, Calvo Bota, Alba Marina, De Francisco Casado, Mª Teresa, Pont Antona, Pere Joan, Gigirey Castro, Orlando, Carvajal, Ángel Francisco, Villena Portella, Cristina, Gómez Bellvert, Cristina, Iglesias, Amanda, Calvo Benito, Javier, Gayà Puig, Antoni, Ortiz, Luis A, Sala-Llinàs, Ernest

“…COPD is a chronic lung disease that affects millions of people, declining their lung function and impairing their life quality. Despite years of research and…”
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Inhibition of antiapoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis, reversing persistent pulmonary fibrosis by Cooley, Joseph C, Javkhlan, Nomin, Wilson, Jasmine A, Foster, Daniel G, Edelman, Benjamin L, Ortiz, Luis A, Schwartz, David A, Riches, David Wh, Redente, Elizabeth F

“…Patients with progressive fibrosing interstitial lung diseases (PF-ILDs) carry a poor prognosis and have limited therapeutic options. A hallmark feature is…”
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