Search Results - "ORIOL, Rafael"

animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach by Harduin-Lepers, Anne, Mollicone, Rosella, Delannoy, Philippe, Oriol, Rafael

“…The animal sialyltransferases are Golgi type II transmembrane glycosyltransferases. Twenty distinct sialyltransferases have been identified in both human and…”
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Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene family: tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes by Harduin-Lepers, Anne, Petit, Daniel, Mollicone, Rosella, Delannoy, Philippe, Petit, Jean-Michel, Oriol, Rafael

“…The animal sialyltransferases, which catalyze the transfer of sialic acid to the glycan moiety of glycoconjugates, are subdivided into four families: ST3Gal,…”
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Activity, Splice Variants, Conserved Peptide Motifs, and Phylogeny of Two New α1,3-Fucosyltransferase Families (FUT10 and FUT11) by Mollicone, Rosella, Moore, Stuart E.H., Bovin, Nicolai, Garcia-Rosasco, Marcela, Candelier, Jean-Jacques, Martinez-Duncker, Iván, Oriol, Rafael

“…We report the cloning of three splice variants of the FUT10 gene, encoding for active α-l-fucosyltransferase-isoforms of 391, 419, and 479 amino acids, and two…”
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Common origin and evolution of glycosyltransferases using Dol-P-monosaccharides as donor substrate by Oriol, Rafael, Martinez-Duncker, Ivan, Chantret, Isabelle, Mollicone, Rosella, Codogno, Patrice

“…On the basis of the analysis of 64 glycosyltransferases from 14 species we propose that several successive duplications of a common ancestral gene, followed by…”
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A Deficiency in Dolichyl-P-glucose:Glc1Man9GlcNAc2-PP-dolichyl α3-Glucosyltransferase Defines a New Subtype of Congenital Disorders of Glycosylation by Chantret, Isabelle, Dancourt, Julia, Dupré, Thierry, Delenda, Christophe, Bucher, Stéphanie, Vuillaumier-Barrot, Sandrine, Ogier de Baulny, Hélène, Peletan, Céline, Danos, Olivier, Seta, Nathalie, Durand, Geneviève, Oriol, Rafael, Codogno, Patrice, Moore, Stuart E.H.

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Lewis histo-blood group system and associated secretory phenotypes by Henry, S, Oriol, R, Samuelsson, B

“…This review summarises present knowledge of the chemistry, immunology, genetics and clinical significance of antibodies in the Lewis and secretor histo-blood…”
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Evolution of Fucosyltransferase Genes in Vertebrates by Costache, Marieta, Apoil, Pol-André, Cailleau, Anne, Elmgren, Anders, Larson, Göran, Henry, Stephen, Blancher, Antoine, Iordachescu, Dana, Oriol, Rafael, Mollicone, Rosella

“…Cloning and expression of chimpanzee FUT3, FUT5, and FUT6 genes confirmed the hypothesis that the gene duplications at the origin of the present human cluster…”
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The nematode Caenorhabditis elegans synthesizes unusual O-linked glycans: identification of glucose-substituted mucin-type O-glycans and short chondroitin-like oligosaccharides by GUÉRARDEL, Yann, BALANZINO, Luis, MAES, Emmanuel, LEROY, Yves, CODDEVILLE, Bernadette, ORIOL, Rafael, STRECKER, Gérard

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Evolution of α2-Fucosyltransferase Genes in Primates: Relation Between an Intronic Alu-Y Element and Red Cell Expression of ABH Antigens by Apoil, Pol-André, Roubinet, Francis, Despiau, Stéphanie, Mollicone, Rosella, Oriol, Rafael, Blancher, Antoine

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Computer simulation of histo-blood group oligosaccharides: energy maps of all constituting disaccharides and potential energy surfaces of 14 ABH and Lewis carbohydrate antigens by Imberty, A, Mikros, E, Koca, J, Mollicone, R, Oriol, R, Pérez, S

“…The three-dimensional structures of fourteen histo-blood groups carbohydrate antigens have been established through a combination of molecular mechanics and…”
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Ancestral Exonic Organization of FUT8, the Gene Encoding the α6-Fucosyltransferase, Reveals Successive Peptide Domains Which Suggest a Particular Three-Dimensional Core Structure for the α6-Fucosyltransferase Family by Javaud, Christophe, Dupuy, Fabrice, Maftah, Abderrahman, Michalski, Jean-Claude, Oriol, Rafael, Petit, Jean-Michel, Julien, Raymond

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Genetics of ABO, H, Lewis, X and related antigens by Oriol, R, Le Pendu, J, Mollicone, R

“…The present knowledge on chemical, enzymatic, serologic and genetic aspects of ABH antigens is reviewed in an effort to produce a simple and coherent genetic…”
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The nematode Caenorhabditis elegans synthesizes unusual O-linked glycans: identification of glucose-substituted mucin-type O-glycans and short chondroitin-like oligosaccharides by GUÉRARDEL, Yann, BALANZINO, Luis, MAES, Emmanuel, LEROY, Yves, CODDEVILLE, Bernadette, ORIOL, Rafael, STRECKER, Gérard

“…The free-living nematode Caenorhabditis elegans is a relevant model for studies on the role of glycoconjugates during development of multicellular organisms…”
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Congenital Disorders of Glycosylation Type Ig Is Defined by a Deficiency in Dolichyl-P-mannose:Man7GlcNAc2-PP-dolichyl Mannosyltransferase by Chantret, Isabelle, Dupré, Thierry, Delenda, Christophe, Bucher, Stéphanie, Dancourt, Julia, Barnier, Anne, Charollais, Aude, Heron, Delphine, Bader-Meunier, Brigitte, Danos, Olivier, Seta, Nathalie, Durand, Geneviève, Oriol, Rafael, Codogno, Patrice, Moore, Stuart E.H.

“…Type I congenital disorders of glycosylation (CDG I) are diseases presenting multisystemic lesions including central and peripheral nervous system deficits…”
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Point Mutations and Deletion Responsible for the Bombay H null and the Reunion H weak Blood Groups by Fernandez-Mateos, Pilar, Cailleau, Anne, Henry, Stephen, Costache, Marieta, Elmgren, Anders, Svensson, Lola, Larson, Göran, Samuelsson, Bo E., Oriol, Rafael, Mollicone, Rosella

“…Objective: Definition of the molecular basis of the Reunion and the Bombay red cell and salivary H‐deficient phenotypes. Methods: Sequence and expression of…”
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Recognition of the blood group H type 2 trisaccharide epitope by 28 monoclonal antibodies and three lectins by Mollicone, R, Cailleau, A, Imberty, A, Gane, P, Perez, S, Oriol, R

“…The patterns of cross-reaction of 30 monoclonal antibodies and three lectins were determined by ELISA with 21 ABH, Ii or Lewis related synthetic…”
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Molecular Phylogeny and Functional Genomics of β-Galactoside α2,6-Sialyltransferases That Explain Ubiquitous Expression of st6gal1 Gene in Amniotes by Petit, Daniel, Mir, Anne-Marie, Petit, Jean-Michel, Thisse, Christine, Delannoy, Philippe, Oriol, Rafael, Thisse, Bernard, Harduin-Lepers, Anne

“…Sialyltransferases are key enzymes in the biosynthesis of sialoglycoconjugates that catalyze the transfer of sialic residue from its activated form to an…”
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Identification of Key Functional Residues in the Active Site of Human β1,4-Galactosyltransferase 7: A MAJOR ENZYME IN THE GLYCOSAMINOGLYCAN SYNTHESIS PATHWAY by Talhaoui, Ibtissam, Bui, Catherine, Oriol, Rafael, Mulliert, Guillermo, Gulberti, Sandrine, Netter, Patrick, Coughtrie, Michael W.H, Ouzzine, Mohamed, Fournel-Gigleux, Sylvie

“…Glycosaminoglycans (GAGs) play a central role in many pathophysiological events, and exogenous xyloside substrates of β1,4-galactosyltransferase 7 (β4GalT7), a…”
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α1,4-Fucosyltransferase Activity: A Significant Function in the Primate Lineage has Appeared Twice Independently by Dupuy, Fabrice, Germot, Agnès, Marenda, Mickaël, Oriol, Rafaël, Blancher, Antoine, Julien, Raymond, Maftah, Abderrahman

“…In the animal kingdom the enzymes that catalyze the formation of alpha1,4 fucosylated-glycoconjugates are known only in apes (chimpanzee) and humans. They are…”
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Genetic complementation reveals a novel human congenital disorder of glycosylation of type II, due to inactivation of the Golgi CMP–sialic acid transporter by Martinez-Duncker, Ivan, Dupré, Thierry, Piller, Véronique, Piller, Friedrich, Candelier, Jean-Jacques, Trichet, Catherine, Tchernia, Gil, Oriol, Rafael, Mollicone, Rosella

“…We have identified a homozygous G>A substitution in the donor splice site of intron 6 (IVS6 + 1G>A) of the cytidine monophosphate (CMP)–sialic acid transporter…”
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