Search Results - "ORCHARD, G."
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Gout With Associated Cutaneous AA Amyloidosis: A Case Report and Review of the Literature
Published in British journal of biomedical science (13-06-2023)“…Gout with associated AA amyloidosis is an unusual finding. This form of amyloid is associated with chronic inflammatory changes often associated with amyloid…”
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Double Immunohistochemical Labelling of PRAME and Melan A in Slow Mohs Biopsy Margin Assessment of Lentigo Maligna and Lentigo Maligna Melanoma
Published in British journal of biomedical science (19-03-2024)“…Lentigo maligna (LM) and lentigo maligna melanoma (LMM) predominantly affect the head and neck areas in elderly patients, presenting as challenging ill-defined…”
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Haematoxylin - the story of the blues
Published in British journal of biomedical science (03-07-2018)Get full text
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Longitudinal association between handgrip strength, gait speed and risk of serious falls in a community-dwelling older population
Published in PloS one (08-05-2023)“…Both grip strength and gait speed can be used as markers of muscle function, however, no previous study has examined them in the same population with respect…”
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The ASPREE Healthy Ageing Biobank: Methodology and participant characteristics
Published in PloS one (29-02-2024)“…ASPirin in Reducing Events in the Elderly (ASPREE), a placebo-controlled prevention trial of low dose aspirin, provided the opportunity to establish a…”
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Evaluation of different haematoxylin stain subtypes for the optimal microscopic interpretation of cutaneous malignancy in Mohs frozen section histological procedure
Published in British journal of biomedical science (03-04-2021)“…The Mohs technique employs mainly H&E-stained frozen sections for surgical margin assessment of cutaneous excisions, utilising microscopic evaluation of the…”
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Short- and long-term impact of aspirin cessation in older adults: a target trial emulation
Published in BMC medicine (29-07-2024)“…The net benefit of aspirin cessation in older adults remains uncertain. This study aimed to use observational data to emulate a randomized trial of aspirin…”
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Evaluation of a New Mordant Based Haematoxylin Dye (Haematoxylin X) for Use in Clinical Pathology
Published in British journal of biomedical science (25-09-2023)“…Recently, St John’s Dermatopathology Laboratory and CellPath Ltd have developed a new patented haematoxylin dye (Haematoxylin X) that utilises a chromium-based…”
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Associations of body size with all-cause and cause-specific mortality in healthy older adults
Published in Scientific reports (07-03-2023)“…In the general population, body mass index (BMI) and waist circumference are recognized risk factors for several chronic diseases and all-cause mortality…”
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British Journal of Biomedical Science in 2021. What have we learned?
Published in British journal of biomedical science (02-10-2021)Get full text
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Daily low‐dose aspirin and blood pressure in community‐dwelling older adults
Published in The journal of clinical hypertension (Greenwich, Conn.) (01-10-2024)“…High‐quality randomized trial evidence is lacking on whether low‐dose aspirin exerts significant effects on blood pressure (BP) in older adults. The authors…”
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Long‐Term Blood Pressure Variability and Risk of Cognitive Decline and Dementia Among Older Adults
Published in Journal of the American Heart Association (06-07-2021)“…Background Blood pressure variability (BPV) in midlife increases risk of late‐life dementia, but the impact of BPV on the cognition of adults who have already…”
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Association of a healthy lifestyle with mortality in older people
Published in BMC geriatrics (11-10-2023)“…Unhealthy lifestyle behaviours such as smoking, high alcohol consumption, poor diet or low physical activity are associated with morbidity and mortality…”
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British Journal of Biomedical Science in 2020. What have we learned?
Published in British journal of biomedical science (01-10-2020)“…Each year the British Journal of Biomedical Science publishes a 'What have we learned' editorial designed to introduce readers within the major disciplines of…”
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Ligand-induced Dimer-Tetramer Transition during the Activation of the Cell Surface Epidermal Growth Factor Receptor-A Multidimensional Microscopy Analysis
Published in The Journal of biological chemistry (26-08-2005)“…The epidermal growth factor receptor (EGFR) is a member of the erbB tyrosine kinase family of receptors. For many years it has been believed that receptor…”
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Potential modifiable factors associated with late-life cognitive trajectories
Published in Frontiers in neurology (03-08-2022)“…There is variability across individuals in cognitive aging. To investigate the associations of several modifiable factors with high and low cognitive…”
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Immunohistochemical detection of V600E BRAF mutation is a useful primary screening tool for malignant melanoma
Published in British journal of biomedical science (03-04-2019)“…Background: We compared the use of an immunohistochemical (IHC) method using a monoclonal antibody to BRAF V600E (which detects the main BRAF mutation) with…”
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Adverse events in older adults and the risk of dementia and cognitive decline
Published in Journal of affective disorders reports (01-07-2023)“…•Adverse events in later-life increases dementia risk.•Increased dementia risk in bereaved individuals.•Increased cognitive decline in men with major financial…”
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The impact of incident stroke on cognitive trajectories in later life
Published in Alzheimer's research & therapy (18-05-2024)“…Cognitive impairment is common after stroke, and a large proportion of stroke patients will develop dementia. However, there have been few large prospective…”
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