Search Results - "OOSTRUM, R"

Expression of the multidrug resistance-associated protein (MRP) gene in human cancers by NOOTER, K, WESTERMAN, A. M, GRATAMA, J. W, KOK, T, EGGERMONT, A. M. M, BOSMAN, F. T, STOTER, G, FLENS, M. J, ZAMAN, G. J. R, SCHEPER, R. J, VAN WINGERDEN, K. E, BURGER, H, OOSTRUM, R, BOERSMA, T, SONNEVELD, P

“…We determined the expression of a newly recognized drug resistance gene, the multidrug resistance-associated protein (MRP) gene, [Cole et al., Science…”
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Expression of the multidrug resistance-associated protein (MRP) gene in primary non-small-cell lung cancer by Nooter, K., Bosman, F. T., Burger, H., van Wingerden, K. E., Flens, M. J., Scheper, R. J., Oostrum, R. G., Boersma, A. W. M., Gaast, A. van der, Stoter, G.

“…Background One of the major problems in the cure of advanced non-small-cell lung cancer (NSCLC) is its lack of re sponse to cytotoxic drug treatment, and the…”
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Constitutive expression of the c-H-ras oncogene inhibits doxorubicin-induced apoptosis and promotes cell survival in a rhabdomyosarcoma cell line by NOOTER, K, BOERSMA, A. W. M, OOSTRUM, R. G, BURGER, H, JOCHEMSEN, A. G, STOTER, G

“…Drugs used in anti-cancer chemotherapy are thought to exert their cytotoxic action by induction of apoptosis. Genes have been identified which can mediate or…”
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Selectivity of compounds isolated from the leaves of Nerium indicum Mill. on various human cancer cell lines by Mae, S H W, Sofia, M, Bolhuis, R L H, Nooter, K, Oostrum, R G, Subagus, W, Ibnu, G G

“…The leaves of Nerium indicum Mill. have been utilized traditionally to cure cancer. By Bioassay (BST) guided isolation method, six compounds were isolated from…”
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Expression of the multidrug resistance-associated protein (MRP) in acute and chronic leukemias by Burger, H, Nooter, K, Zaman, G J, Sonneveld, P, van Wingerden, K E, Oostrum, R G, Stoter, G

“…We determined the expression of the multidrug resistance-associated protein (MRP), a new putative transmembrane drug transporter, in peripheral blood cells…”
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Silicon thickness variation of FD-SOI wafers investigated by differential reflective microscopy by Auerhammer, J., Hartig, C., Wendt, K., van Oostrum, R., Pfeiffer, G., Bayer, S., Srocka, B.

“…Fully depleted silicon-on-insulator (FD-SOI) wafers with very thin Si top layers in the range of ten nanometers have to fulfill very strict uniformity…”
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Competitive facility location: the Voronoi game by Ahn, Hee-Kap, Cheng, Siu-Wing, Cheong, Otfried, Golin, Mordecai, van Oostrum, René

“…We consider a competitive facility location problem with two players. Players alternate placing points, one at a time, into the playing arena, until each of…”
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Parametric search made practical by van Oostrum, René, Veltkamp, Remco C.

“…In this paper we show that in sorting-based applications of parametric search, Quicksort can replace the parallel sorting algorithms that are usually…”
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Quantification of apoptotic cells with fluorescein isothiocyanate‐labeled annexin V in chinese hamster ovary cell cultures treated with cisplatin by Boersma, Antonius W. M., Nooter, Kees, Oostrum, Robert G., Stoter, Gerrit

“…Plasma membrane binding of annexin V was used to detect and quantitate apoptotic cells induced by cytotoxic drug treatment in epithelial cell cultures. Chinese…”
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Expression of mdr1 and mdr3 multidrug-resistance genes in hairy cell leukaemia by Herweijer, H, Nooter, K, Beishuizen, A, Sonneveld, P, Oostrum, R G, Hesseling-Janssen, A L, van Dongen, J J

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Casting a polyhedron with directional uncertainty by Ahn, Hee-Kap, Cheong, Otfried, van Oostrum, René

“…Casting is a manufacturing process in which molten material is poured into a cast (mould), which is opened after the material has solidified. As in all…”
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Hierarchical Decompositions and Circular Ray Shooting in Simple Polygons by Cheng, Siu-Wing, Cheong, Otfried, Everett, Hazel, van Oostrum, René

“…A hierarchical decomposition of a simple polygon is introduced. The hierarchy has logarithmic depth, linear size, and its regions have at most three neighbors…”
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Facility Location on a Polyhedral Surface by Aronov, Boris, van Kreveld, Marc, van Oostrum, Ren, Varadarajan, Kasturi

“…Given an orientable genus-0 polyhedral surface defined by n triangles, and a set of m point sites} on it, we would like to identify its 1-center, i.e., the…”
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Expression of the mdr3 gene in prolymphocytic leukemia: association with cyclosporin-A-induced increase in drug accumulation by Nooter, K, Sonneveld, P, Janssen, A, Oostrum, R, Boersma, T, Herweijer, H, Valerio, D, Hagemeijer, A, Baas, F

“…Typical multidrug resistance in human and animal cell lines is caused by overactivity of an unidirectional transmembrane drug efflux pump, encoded by the MDR…”
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Effect of cyclosporin A on daunorubicin accumulation in multidrug-resistant P388 leukemia cells measured by real-time flow cytometry by Nooter, K, Oostrum, R, Jonker, R, van Dekken, H, Stokdijk, W, van den Engh, G

“…We investigated the mode of action of cyclosporin A (Cy-A) as a modifier of multidrug resistance in P388 mouse leukemia cells. A fluorescence-activated flow…”
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Effects of verapamil on the pharmacokinetics of daunomycin in the rat by NOOTER, K, OOSTRUM, R, DUERLOO, J

“…We compared the pharmacokinetics of daunomycin in two groups of rats: one group was treated with daunomycin (7.5 mg/kg) alone and the other group was treated…”
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Overexpression of the mdr1 gene in blast cells from patients with acute myelocytic leukemia is associated with decreased anthracycline accumulation that can be restored by cyclosporin-A by Nooter, K, Sonneveld, P, Oostrum, R, Herweijer, H, Hagenbeek, T, Valerio, D

“…Typical multi-drug resistance (MDR) in human and animal cell lines is caused by overactivity of a unidirectional drug efflux pump. This pump is composed of a…”
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Effect of cyclosporin A on daunorubicin accumulation in multidrug-resistant P388 leukemia cells measured by real-time cytometry by NOOTER, K, OOSTRUM, R, JONKER, R, VAN DEKKEN, H, STOKDIJK, W, VAN DEN ENGH, G

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Repeated daunomycin administration in rats: pharmacokinetics and bone marrow toxicity by NOOTER, K, SONNEVELD, P, DEURLOO, J, OOSTRUM, R, SCHULTZ, F, MARTENS, A, HAGENBEEK, A

“…In the experiments described here, rats received three IV bolus injections (7.5 mg/kg) of daunomycin. The plasma data obtained after a single IV injection…”
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Blood and tissue distribution of cyclosporin A after a single oral dose in the rat by Nooter, K, Meershoek, B, Spaans, W, Sonneveld, P, Oostrum, R, Deurloo, J

“…After a single oral dose of cyclosporin A (82 mg/kg) in rats, tissue (kidneys liver and brain) and blood levels reached maximum values (approximately 80…”
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