Search Results - "ONO, TOSHIHIDE"

Assessment of prediction accuracy of protein function from protein–protein interaction data by Hishigaki, Haretsugu, Nakai, Kenta, Ono, Toshihide, Tanigami, Akira, Takagi, Toshihisa

“…Functional prediction of open reading frames coded in the genome is one of the most important tasks in yeast genomics. Among a number of large‐scale…”
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Gene Expression Analysis during Platelet-Like Particle Production in Phorbol Myristate Acetate-Treated MEG-01 Cells by Isakari, Yoshimasa, Sogo, Shinji, Ishida, Tatsuhiro, Kawakami, Takuma, Ono, Toshihide, Taki, Takao, Kiwada, Hiroshi

“…A comprehensive gene-expression analysis during platelet (PLT) production from megakaryocytes may give important information on genes involved in the PLT…”
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A radiation hybrid map of the rat genome containing 5,255 markers by Yamasaki, Yuki, Watanabe, Takeshi K, Kanemoto, Naohide, Oga, Keiko, Irie, Yasuo, Browne, Julie, Adachi, Masakazu, Kiguwa, Susanna L, James, Michael R, Critcher, Ricky, Hayashi, Hiromi, Lathrop, G. Mark, Knights, Catherine, Webber, Caleb, Ono, Toshihide, Davis, Marie, Nakamura, Yusuke, Tanigami, Akira, Thangarajah, Thiru, Goodfellow, Peter N, Tsuji, Atsushi, Takahashi, Ei-ichi, Mizoguchi-Miyakita, Ayako, Kiel, Susanne, Hishigaki, Haretsugu, Day, Philip J.R, Miller, Jonathan, Smith, Angela, Tomita, Kazuhiro, Hudson, James R, McCarthy, Linda C, Bihoreau, Marie-Therese, Takagi, Toshihisa, Okuno, Shiro

“…A whole-genome radiation hybrid (RH) panel was used to construct a high-resolution map of the rat genome based on microsatellite and gene markers. These…”
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CD41+/CD45+ Cells Without Acetylcholinesterase Activity Are Immature and a Major Megakaryocytic Population in Murine Bone Marrow by Matsumura‐Takeda, Kuniko, Sogo, Shinji, Isakari, Yoshimasa, Harada, Yasuo, Nishioka, Kinue, Kawakami, Takuma, Ono, Toshihide, Taki, Takao

“…Murine megakaryocytes (MKs) are defined by CD41/CD61 expression and acetylcholinesterase (AChE) activity; however, their stages of differentiation in bone…”
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MUTATED G-PROTEIN-COUPLED RECEPTOR GPR10 IS RESPONSIBLE FOR THE HYPERPHAGIA/DYSLIPIDAEMIA/OBESITY LOCUS OF Dmo1 IN THE OLETF RAT by Watanabe, Takeshi K, Suzuki, Mikio, Yamasaki, Yuki, Okuno, Shiro, Hishigaki, Haretsugu, Ono, Toshihide, Oga, Keiko, Mizoguchi-Miyakita, Ayako, Tsuji, Atsushi, Kanemoto, Naohide, Wakitani, Shigeyuki, Takagi, Toshihisa, Nakamura, Yusuke, Tanigami, Akira

“…SUMMARY 1. We have confirmed the Diabetes Mellitus OLETF type I (Dmo1) effect on hyperphagia, dyslipidaemia and obesity in the Otsuka Long‐Evans Tokushima…”
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A novel method for gathering and prioritizing disease candidate genes based on construction of a set of disease-related MeSH® terms by Ono, Toshihide, Kuhara, Satoru

“…Understanding the molecular mechanisms involved in disease is critical for the development of more effective and individualized strategies for prevention and…”
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Prediction of GPCR-G Protein Coupling Specificity Using Features of Sequences and Biological Functions by Ono, Toshihide, Hishigaki, Haretsugu

“…Understanding the coupling specificity between G protein-coupled receptors (GPCRs) and specific classes of G proteins is important for further elucidation of…”
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A novel method for gathering and prioritizing disease candidate genes based on construction of a set of disease-related MeSH registered terms by Ono, Toshihide, Kuhara, Satoru

“…Background: Understanding the molecular mechanisms involved in disease is critical for the development of more effective and individualized strategies for…”
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Automated extraction of information on protein–protein interactions from the biological literature by Ono, Toshihide, Hishigaki, Haretsugu, Tanigami, Akira, Takagi, Toshihisa

“…Motivation: To understand biological process, we must clarify how proteins interact with each other. However, since information about protein–protein…”
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Single-Allele Correction Of The Dmo1 Locus In Congenic Animals Substantially Attenuates Obesity, Dyslipidaemia And Diabetes Phenotypes Of The Oletf Rat by Watanabe, Takeshi K, Okuno, Shiro, Ono, Toshihide, Yamasaki, Yuki, Oga, Keiko, Mizoguchi-Miyakita, Ayako, Miyao, Hideo, Suzuki, Mikio, Momota, Hiroshi, Goto, Yoshihiro, Shinomiya, Hiroichi, Hishigaki, Haretsugu, Hayashi, Isamu, Asai, Toshihiro, Wakitani, Shigeyuki, Takagi, Toshihisa, Nakamura, Yusuke, Tanigami, Akira

“…SUMMARY 1. Whole‐genome scans have identified Dmo1 as a major quantitative trait locus for dyslipidaemia and obesity in the Otsuka Long Evans Tokushima Fatty…”
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Genetic analysis of pancreatic duct hyperplasia in Otsuka Long-Evans Tokushima Fatty rats: Possible association with a region on rat chromosome 14 that includes the disrupted cholecystokinin-A receptor gene by Kanemoto, Naohide, Kondo, Mari, Iwanaga, Tomoyuki, Hishigaki, Haretsugu, Ono, Toshihide, Mizoguchi-Miyakita, Ayako, Oga, Keiko, Tsuji, Atsushi, Okuno, Shiro, Watanabe, Takeshi K., Nose, Masato, Tanigami, Akira

“…An Otsuka Long–Evans Tokushima Fatty (OLETF) strain of rat spontaneously developed hyperglycemia, hyperinsulinemia, insulin resistance and mild obesity, which…”
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Automatic Extraction of Information on Protein-Protein Interaction from Scientific Literature by Ono, Toshihide, Hishigaki, Haretsugu, Tanigami, Akira, Takagi, Toshihisa

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Interaction-Based Analysis of Protein Function and Network by Hishigaki, Haretsugu, Ono, Toshihide, Tanigami, Akira, Takagi, Toshihisa

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WebPACADE: A System for the Analysis of Structural Similarity of Protein via WWW by Satou, Kenji, Ono, Toshihide, Nakanishi, Yukiko, Furuichi, Emiko, Kuhara, Satoru, Takagi, Toshihisa

“…This paper describes on a developmental system WebPACADE which is an extended version of a deductive database system PACADE for the analysis of protein 3D…”
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CD41 super(+)/CD45 super(+) Cells Without Acetylcholinesterase Activity Are Immature and a Major Megakaryocytic Population in Murine Bone Marrow by Matsumura-Takeda, Kuniko, Sogo, Shinji, Isakari, Yoshimasa, Harada, Yasuo, Nishioka, Kinue, Kawakami, Takuma, Ono, Toshihide, Taki, Takao

“…Murine megakaryocytes (MKs) are defined by CD41/CD61 expression and acetylcholinesterase (AChE) activity; however, their stages of differentiation in bone…”
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Identification of New Megakaryocytic Subpopulations in Mouse Bone Marrow by Sogo, Shinji, Matsumura-Takeda, Kuniko, Isakari, Yoshimasa, Harada, Yasuo, Nishioka, Kinue, Kawakami, Takuma, Ono, Toshihide, Taki, Takao

“…Platelets (PLT) are produced from megakaryocytes (Mks) via proplatelet formation (PPF). However, the molecular mechanisms from Mks to PPF are not clearly…”
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Effects of Dmo1 on obesity, dyslipidaemia and hyperglycaemia in the Otsuka Long Evans Tokushima Fatty strain by Okuno, S, Watanabe, T K, Ono, T, Oga, K, Mizoguchi-Miyakita, A, Yamasaki, Y, Goto, Y, Shinomiya, H, Momota, H, Miyao, H, Hayashi, I, Asai, T, Suzuki, M, Harada, Y, Hishigaki, H, Wakitani, S, Takagi, T, Nakamura, Y, Tanigami, A

“…Whole-genome scans have identified Dmo1 as a major quantitative trait locus (QTL) for obesity and dyslipidaemia in the Otsuka Long Evans Tokushima Fatty…”
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A < 1.7 cM interval is responsible for Dmo1 obesity phenotypes in OLETF rats by Watanabe, Takeshi K, Okuno, Shiro, Yamasaki, Yuki, Ono, Toshihide, Oga, Keiko, Mizoguchi-Miyakita, Ayako, Miyao, Hideo, Suzuki, Mikio, Momota, Hiroshi, Goto, Yoshihiro, Shinomiya, Hiroichi, Hishigaki, Haretsugu, Hayashi, Isamu, Asai, Toshihiro, Wakitani, Shigeyuki, Takagi, Toshihisa, Nakamura, Yusuke, Tanigami, Akira

“…Summary 1. Dmo1 (Diabetes Mellitus OLETF type I) is a major quantitative trait locus for dyslipidaemia, obesity and diabetes phenotypes of male Otsuka Long…”
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Genetic determinants of plasma triglyceride levels in (OLETF x BN) x OLETF backcross rats by Okuno, S, Watanabe, T K, Ono, T, Yamasaki, Y, Goto, Y, Miyao, H, Asai, T, Kanemoto, N, Oga, K, Mizoguchi-Miyakita, A, Takagi, T, Takahashi, E, Nakamura, Y, Tanigami, A

“…Altered lipid metabolism is closely associated with diabetes in humans, although predisposing genetic factors that affect hyperlipidemia have not yet been…”
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Confirmation of a Major QTL, Dmo1, Linked to Obesity, Dyslipidemia and Hyperglycemia in the Otsuka Long Evans Tokushima Fatty by SUZUKI, MIKIO, WATANABE, TAKESHI K, OKUNO, SHIRO, YAMASAKI, YUKI, ONO, TOSHIHIDE, OGA, KEIKO, MIZOGUCHI-MIYAKITA, AYAKO, MIYAO, HIDEO, MOMOTA, HIROSHI, GOTO, YOSHIHIRO, SHINOMIYA, HIROICHI, HAYASHI, ISAMU, ASAI, TOSHIHIRO, TANIGAMI, AKIRA

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