Search Results - "ONAMI, Saeko"

Spontaneous histiocytic sarcoma originating from the epididymis in a CD-1 mouse by Shimazaki, Taishi, Yasui, Yuzo, Anagawa-Nakamura, Akiko, Toyoda, Kaoru, Yamazaki, Ryo, Onami, Saeko, Kemmochi, Yusuke, Shoda, Toshiyuki

“…We report a histiocytic sarcoma originating from the epididymis observed in a 110-week-old male CD-1 mouse in a carcinogenicity study. At necropsy, no lesions…”
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A 13-week repeated dose study of three 3-monochloropropane-1,2-diol fatty acid esters in F344 rats by Onami, Saeko, Cho, Young-man, Toyoda, Takeshi, Mizuta, Yasuko, Yoshida, Midori, Nishikawa, Akiyoshi, Ogawa, Kumiko

“…3-monochloropropane-1,2-diol (3-MCPD), a rat renal and testicular carcinogen, has been reported to occur in various foods and food ingredients as free or…”
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Orally administered glycidol and its fatty acid esters as well as 3-MCPD fatty acid esters are metabolized to 3-MCPD in the F344 rat by Onami, Saeko, Cho, Young-Man, Toyoda, Takeshi, Akagi, Jun-ichi, Fujiwara, Satoshi, Ochiai, Ryosuke, Tsujino, Kazushige, Nishikawa, Akiyoshi, Ogawa, Kumiko

“…IARC has classified glycidol and 3-monochloropropane-1,2-diol (3-MCPD) as group 2A and 2B, respectively. Their esters are generated in foodstuffs during…”
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Absence of in vivo genotoxicity of 3-monochloropropane-1,2-diol and associated fatty acid esters in a 4-week comprehensive toxicity study using F344 gpt delta rats by Onami, Saeko, Cho, Young-Man, Toyoda, Takeshi, Horibata, Katsuyoshi, Ishii, Yuji, Umemura, Takashi, Honma, Masamitsu, Nohmi, Takehiko, Nishikawa, Akiyoshi, Ogawa, Kumiko

“…3-Monochloropropane-1,2-diol (3-MCPD) is regarded as a rat renal and testicular carcinogen and has been classified as a possible human carcinogen (group 2B) by…”
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Dosimetry for lung tumorigenesis induced by urethane, 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK), and benzo[a]pyrene (B[a]P) in A/JJmsSlc mice by Onami, Saeko, Okubo, Chigusa, Iwanaga, Asuka, Suzuki, Hiroaki, Iida, Hajime, Motohashi, Yurie, Tomonari, Yuki, Otake, Seiji, Tsuji, Hiroyuki, Yoshimura, Hiroyuki

“…Some chemicals are known to be lung carcinogens in rodents. While many studies using two-stage models have administered medium or high doses to mice, few have…”
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Detection of γ-H2AX, a Biomarker for DNA Double-strand Breaks, in Urinary Bladders of N-Butyl-N-(4-Hydroxybutyl)-Nitrosamine-Treated Rats by TOYODA, Takeshi, AKAGI, Jun-ichi, CHO, Young-Man, MIZUTA, Yasuko, ONAMI, Saeko, SUZUKI, Isamu, OGAWA, Kumiko

“…To evaluate the potential role of DNA repair in bladder carcinogenesis, we performed an immunohistochemical analysis of expression of various DNA repair…”
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Undifferentiated Sarcoma of the Salivary Gland in a Mongolian Gerbil (Meriones unguiculatus) by Toyoda, Takeshi, Tsukamoto, Tetsuya, Cho, Young-Man, Onami, Saeko, Takasu, Shinji, Shi, Liang, Saito, Ayumi, Matsuo, Saori, Tatematsu, Masae, Nishikawa, Akiyoshi, Ogawa, Kumiko

“…A subcutaneous mass was found in the lower ventral neck region of a 55-week-old male Mongolian gerbil (Meriones unguiculatus). Histopathologically, the mass…”
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Detection of γ-H2AX, a Biomarker for DNA Double-strand Breaks, in Urinary Bladders of N-Butyl-N-(4-Hydroxybutyl)-Nitrosamine-Treated Rats by Takeshi Toyoda, Jun-ichi Akagi, Young-Man Cho, Yasuko Mizuta, Saeko Onami, Isamu Suzuki, Kumiko Ogawa

“…「Abstract」: To evaluate the potential role of DNA repair in bladder carcinogenesis, we performed an immunohistochemical analysis of expression of various DNA…”
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Spontaneous histiocytic sarcoma originating from the epididymis in a CD-1 mouse by SHIMAZAKI, Taishi, YASUI, Yuzo, ANAGAWA-NAKAMURA, Akiko, TOYODA, Kaoru, YAMAZAKI, Ryo, ONAMI, Saeko, KEMMOCHI, Yusuke, SHODA, Toshiyuki

“…We report a histiocytic sarcoma originating from the epididymis observed in a 110-week-old male CD-1 mouse in a carcinogenicity study. At necropsy, no lesions…”
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Characterization of biochemical, functional and structural changes in mice respiratory organs chronically exposed to cigarette smoke by Tsuji, Hiroyuki, Fujimoto, Hitoshi, Lee, Kyeonghee Monica, Renne, Roger, Iwanaga, Asuka, Okubo, Chigusa, Onami, Saeko, Nomura, Ayako Koizumi, Nishino, Tomoki, Yoshimura, Hiroyuki

“…Female C57BL/6 mice were exposed to mainstream cigarette smoke at 600 μg WTPM/L, 4 h/day and 5 days/week for up to 52 weeks. At 26, 52 and 65 weeks (52 weeks…”
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Detection of [gamma]-H2AX, a Biomarker for DNA Double-strand Breaks, in Urinary Bladders of N-Butyl-N-(4-Hydroxybutyl)-Nitrosamine-Treated Rats by TOYODA, Takeshi, AKAGI, Jun-ichi, CHO, Young-Man, MIZUTA, Yasuko, ONAMI, Saeko, SUZUKI, Isamu, OGAWA, Kumiko

“…To evaluate the potential role of DNA repair in bladder carcinogenesis, we performed an immunohistochemical analysis of expression of various DNA repair…”
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Undifferentiated Sarcoma of the Salivary Gland in a Mongolian Gerbil (Meriones unguiculatus) by Toyoda, Takeshi, Tsukamoto, Tetsuya, Cho, Young-Man, Onami, Saeko, Takasu, Shinji, Shi, Liang, Saito, Ayumi, Matsuo, Saori, Tatematsu, Masae, Nishikawa, Akiyoshi, Ogawa, Kumiko

“…A subcutaneous mass was found in the lower ventral neck region of a 55-week-old male Mongolian gerbil (Meriones unguiculatus). Histopathologically, the mass…”
Get full text