Search Results - "ONA WU"
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A human memory circuit derived from brain lesions causing amnesia
Published in Nature communications (02-08-2019)“…Human memory is thought to depend on a circuit of connected brain regions, but this hypothesis has not been directly tested. We derive a human memory circuit…”
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2
Functional networks reemerge during recovery of consciousness after acute severe traumatic brain injury
Published in Cortex (01-09-2018)“…Integrity of the default mode network (DMN) is believed to be essential for human consciousness. However, the effects of acute severe traumatic brain injury…”
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3
Lesions causing hallucinations localize to one common brain network
Published in Molecular psychiatry (01-04-2021)“…The brain regions responsible for hallucinations remain unclear. We studied 89 brain lesions causing hallucinations using a recently validated technique termed…”
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4
Infarct topography and functional outcomes
Published in Journal of Cerebral Blood Flow & Metabolism (01-09-2018)“…Acute ischemic stroke represents a major cause of long-term adult disability. Accurate prognostication of post-stroke functional outcomes is invaluable in…”
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5
Neuroanatomic Connectivity of the Human Ascending Arousal System Critical to Consciousness and Its Disorders
Published in Journal of neuropathology and experimental neurology (01-06-2012)“…ABSTRACTThe ascending reticular activating system (ARAS) mediates arousal, an essential component of human consciousness. Lesions of the ARAS cause coma, the…”
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Intravenous thrombolysis in unwitnessed stroke onset: MR WITNESS trial results
Published in Annals of neurology (01-05-2018)“…Objective Most acute ischemic stroke (AIS) patients with unwitnessed symptom onset are ineligible for intravenous thrombolysis due to timing alone. Lesion…”
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Neuroprognostication of hypoxic–ischaemic coma in the therapeutic hypothermia era
Published in Nature reviews. Neurology (01-04-2014)“…Key Points Therapeutic hypothermia (TH) influences the time course of neurological recovery after cardiac arrest, and the influence of added sedation is also…”
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8
Role of Acute Lesion Topography in Initial Ischemic Stroke Severity and Long-Term Functional Outcomes
Published in Stroke (1970) (01-09-2015)“…BACKGROUND AND PURPOSE—Acute infarct volume, often proposed as a biomarker for evaluating novel interventions for acute ischemic stroke, correlates only…”
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In patients with suspected acute stroke, CT perfusion-based cerebral blood flow maps cannot substitute for DWI in measuring the ischemic core
Published in PloS one (30-11-2017)“…Neuroimaging may guide acute stroke treatment by measuring the volume of brain tissue in the irreversibly injured "ischemic core." The most widely accepted…”
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10
Brain Edema Predicts Outcome After Nonlacunar Ischemic Stroke
Published in Stroke (1970) (01-12-2014)“…BACKGROUND AND PURPOSE—In malignant infarction, brain edema leads to secondary neurological deterioration and poor outcome. We sought to determine whether…”
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DWI-FLAIR mismatch for the identification of patients with acute ischaemic stroke within 4·5 h of symptom onset (PRE-FLAIR): a multicentre observational study
Published in Lancet neurology (01-11-2011)“…Summary Background Many patients with stroke are precluded from thrombolysis treatment because the time from onset of their symptoms is unknown. We aimed to…”
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12
Outcome after acute ischemic stroke is linked to sex-specific lesion patterns
Published in Nature communications (02-06-2021)“…Acute ischemic stroke affects men and women differently. In particular, women are often reported to experience higher acute stroke severity than men. We…”
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13
Microinfarct disruption of white matter structure: A longitudinal diffusion tensor analysis
Published in Neurology (08-07-2014)“…OBJECTIVE:To evaluate the local effect of small asymptomatic infarctions detected by diffusion-weighted imaging (DWI) on white matter microstructure using…”
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14
Acute Stroke Imaging Research Roadmap II
Published in Stroke (1970) (01-09-2013)Get full text
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15
Predicting Clinical Outcome in Comatose Cardiac Arrest Patients Using Early Noncontrast Computed Tomography
Published in Stroke (1970) (01-04-2011)“…Early assessment of the likelihood of neurological recovery in comatose cardiac arrest survivors remains challenging. We hypothesize that quantitative…”
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16
Consensus statement on current and emerging methods for the diagnosis and evaluation of cerebrovascular disease
Published in Journal of Cerebral Blood Flow & Metabolism (01-09-2018)“…Cerebrovascular disease (CVD) remains a leading cause of death and the leading cause of adult disability in most developed countries. This work summarizes…”
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An anorexia nervosa network derived from human brain lesions
Published in Brain stimulation (01-01-2023)Get full text
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18
Clinical examination for prognostication in comatose cardiac arrest patients
Published in Resuscitation (01-11-2013)“…Abstract Objective To build new algorithms for prognostication of comatose cardiac arrest patients using clinical examination, and investigate whether…”
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19
Diffusion tensor imaging in acute-to-subacute traumatic brain injury: a longitudinal analysis
Published in BMC neurology (11-01-2016)“…Diffusion tensor imaging (DTI) may have prognostic utility in patients with traumatic brain injury (TBI), but the optimal timing of DTI data acquisition is…”
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Comparison of 10 Perfusion MRI Parameters in 97 Sub-6-Hour Stroke Patients Using Voxel-Based Receiver Operating Characteristics Analysis
Published in Stroke (1970) (01-06-2009)“…Perfusion-weighted imaging can predict infarct growth in acute stroke and potentially be used to select patients with tissue at risk for reperfusion therapies…”
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