Search Results - "OMACHI, A"

Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials by Gevaert, Philippe, Omachi, Theodore A., Corren, Jonathan, Mullol, Joaquim, Han, Joseph, Lee, Stella E., Kaufman, Derrick, Ligueros-Saylan, Monica, Howard, Monet, Zhu, Rui, Owen, Ryan, Wong, Kit, Islam, Lutaf, Bachert, Claus

“…Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by IgE hyperproduction and eosinophilic inflammation. The anti-IgE antibody, omalizumab, has…”
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Measures of sleep in rheumatologic diseases: Epworth Sleepiness Scale (ESS), Functional Outcome of Sleep Questionnaire (FOSQ), Insomnia Severity Index (ISI), and Pittsburgh Sleep Quality Index (PSQI) by Omachi, Theodore A.

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A randomized multicenter study evaluating Xolair persistence of response after long-term therapy by Ledford, Dennis, Busse, William, Trzaskoma, Benjamin, Omachi, Theodore A, Rosén, Karin, Chipps, Bradley E, Luskin, Allan T, Solari, Paul G

“…Few data are available to assist clinicians with decisions regarding long-term use of asthma therapies, including omalizumab. We sought to evaluate the benefit…”
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Response to omalizumab using patient enrichment criteria from trials of novel biologics in asthma by Casale, T. B., Chipps, B. E., Rosén, K., Trzaskoma, B., Haselkorn, T., Omachi, T. A., Greenberg, S., Hanania, N. A.

“…Background Recent efficacy studies of asthma biologics have included highly enriched patient populations. Using a similar approach, we examined factors that…”
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Timing and duration of omalizumab response in patients with chronic idiopathic/spontaneous urticaria by Kaplan, Allen, MD, Ferrer, Marta, MD, PhD, Bernstein, Jonathan A., MD, Antonova, Evgeniya, MS, PhD, Trzaskoma, Benjamin, MS, Raimundo, Karina, MS, Rosén, Karin, MD, PhD, Omachi, Theodore A., MD, MBA, Khalil, Sam, PhD, Zazzali, James L., PhD, MPH

“…Background Few data are available that describe response patterns in patients with chronic idiopathic urticaria (CIU)/chronic spontaneous urticaria (CSU)…”
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Long-term efficacy and safety of omalizumab for nasal polyposis in an open-label extension study by Gevaert, Philippe, Saenz, Rebecca, Corren, Jonathan, Han, Joseph K., Mullol, Joaquim, Lee, Stella E., Ow, Randall A., Zhao, Rui, Howard, Monet, Wong, Kit, Islam, Lutaf, Ligueros-Saylan, Monica, Omachi, Theodore A., Bachert, Claus

“…Chronic rhinosinusitis with nasal polyps (CRSwNP) frequently remains uncontrolled despite maximal medical therapy and sinonasal surgery, presenting several…”
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Socioeconomic status, race and COPD health outcomes by Eisner, M D, Blanc, P D, Omachi, T A, Yelin, E H, Sidney, S, Katz, P P, Ackerson, L M, Sanchez, G, Tolstykh, Irina, Iribarren, C

“…BackgroundAlthough chronic obstructive pulmonary disease (COPD) is a common cause of death and disability, little is known about the effects of socioeconomic…”
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Cardiovascular and cerebrovascular events among patients receiving omalizumab: Results from EXCELS, a prospective cohort study in moderate to severe asthma by Iribarren, Carlos, MD, MPH, PhD, Rahmaoui, Abdelkader, MD, Long, Aidan A., MD, Szefler, Stanley J., MD, Bradley, Mary S., MS, Carrigan, Gillis, PhD, MSc, Eisner, Mark D., MD, MPH, Chen, Hubert, MD, MPH, Omachi, Theodore A., MD, MBA, Farkouh, Michael E., MD, MSc, Rothman, Kenneth J., DrPH

“…Background EXCELS, a postmarketing observational cohort study, was a commitment to the US Food and Drug Administration to assess the long-term safety of…”
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Depression and Health-Related Quality of Life in Chronic Obstructive Pulmonary Disease by Omachi, Theodore A., MD, MBA, Katz, Patricia P., PhD, Yelin, Edward H., PhD, Gregorich, Steven E., PhD, Iribarren, Carlos, MD, MPH, PhD, Blanc, Paul D., MD, MSPH, Eisner, Mark D., MD, MPH

“…Abstract Background Prior research on the risk of depression in chronic obstructive pulmonary disease (COPD) has yielded conflicting results. Furthermore, we…”
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Influence of anxiety on health outcomes in COPD by Eisner, Mark D, Blanc, Paul D, Yelin, Edward H, Katz, Patricia P, Sanchez, Gabriela, Iribarren, Carlos, Omachi, Theodore A

“…Psychological functioning is an important determinant of health outcomes in chronic lung disease. To better define the role of anxiety in chronic obstructive…”
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Correlation between crystal structure and superconductivity in LaO0.5F0.5BiS2 by Kajitani, J., Deguchi, K., Omachi, A., Hiroi, T., Takano, Y., Takatsu, H., Kadowaki, H., Miura, O., Mizuguchi, Y.

“…Correlation between crystal structure and superconducting properties of the BiS2-based superconductor LaO0.5F0.5BiS2 was investigated. We have prepared…”
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Sleep Apnea and Obstructive Airway Disease in Older Men: Outcomes of Sleep Disorders in Older Men Study by Zhao, Ying Y, Blackwell, Terri, Ensrud, Kristine E, Stone, Katie L, Omachi, Theodore A, Redline, Susan

“…To evaluate the association between obstructive airway disease (OAD) and sleep apnea in older men. A community-based cross-sectional study of 853…”
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Asthma exacerbations and lung function in patients with severe or difficult-to-treat asthma by Calhoun, William J., MD, Haselkorn, Tmirah, PhD, Miller, Dave P., MS, Omachi, Theodore A., MD, MBA

“…Patients with exacerbations were more likely to have 3 or more control problems compared with those without exacerbations (41% vs 19%) and less likely to have…”
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Meaningful changes for efficacy outcomes in patients with chronic rhinosinusitis with nasal polyps by Braid, Jessica, Islam, Lutaf, Gugiu, Cristian, Omachi, Theodore A., Doll, Helen

“…Nasal Polyp Score (NPS) and Nasal Congestion Score (NCS) are commonly used clinical trial endpoints to determine improvements in response to treatment in…”
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Development of disability in chronic obstructive pulmonary disease: beyond lung function by Eisner, Mark D, Iribarren, Carlos, Blanc, Paul D, Yelin, Edward H, Ackerson, Lynn, Byl, Nancy, Omachi, Theodore A, Sidney, Stephen, Katz, Patricia P

“…COPD is a major cause of disability, but little is known about how disability develops in this condition. The authors analysed data from the Function, Living,…”
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Poor Asthma Control Is Associated with Overall Daily Activity Impairment: 3-Year Data from the EXCELS Study of Omalizumab by Antonova, Evgeniya, MS, PhD, Trzaskoma, Benjamin, MS, Omachi, Theodore A., MD, MBA, Schatz, Michael, MD, MS, FAAAAI

“…Patients reported asthma control via the Asthma Control Test (ACT; well-controlled [ACT>19] vs poorly-controlled [ACT<=19]) and productivity impairment via the…”
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Higher Immunoglobulin E (IgE) Levels Are Associated with Greater Emergency Care and Other Healthcare Utilization Among Asthma Patients in a Real-World Data Setting by Luskin, Allan T., MD, Antonova, Evgeniya, MS, PhD, Broder, Michael, MD, MSHS, Chang, Eunice, PhD, Omachi, Theodore A., MD, MBA

“…High-IgE patients were more likely to have used allergen immunotherapy (18.2% vs 10.9%; p=0.008), chronic oral corticosteroids (OCS) (33.6% vs 26.0%; p=0.034),…”
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Blood Eosinophils and Serum IgE Predict Response to Omalizumab in Patients with Severe Allergic Asthma: Innovate Trial Post-Hoc Analysis by Manga, Volkan, MD, Humbert, Marc, MD, PhD, Djukanovic, Ratko, Greenberg, Steve, MD, Omachi, Theodore A., MD, MBA, Trzaskoma, Benjamin, MS, Buhl, Roland

“…Allergy 2005) was performed to determine the impact of treatment on exacerbation rates and health-related quality-of-life (AQLQ) of SAA patients stratified by…”
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Exploratory Analysis of the Roles of Multiple Biomarkers in Predicting Response to Omalizumab in Allergic Asthma by Busse, William W., MD, FAAAAI, Rosén, Karin, MD, PhD, Manga, Volkan, MD, Trzaskoma, Benjamin, MS, Omachi, Theodore A., MD, MBA

“…Rationale Biomarkers of Type-2 (Th2-high) inflammation, such as fractional exhaled nitric oxide (FeNO) and peripheral blood eosinophils (EOS), appear to…”
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Matrix metalloproteinase-9 predicts pulmonary status declines in α1-antitrypsin deficiency by Omachi, Theodore A, Eisner, Mark D, Rames, Alexis, Markovtsova, Lada, Blanc, Paul D

“…Matrix metalloproteinase-9 (MMP-9) may be important in the progression of emphysema, but there have been few longitudinal clinical studies of MMP-9 including…”
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