Search Results - "OLSON, Lawrence Karl"
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Cigarette smoke components inhibited intercellular communication and differentiation in human pancreatic ductal epithelial cells
Published in International journal of cancer (01-05-2007)“…Smoking is a well‐documented risk factor for the development of pancreatic adenocarcinoma. Although the most abundant polycyclic aromatic hydrocarbons (PAHs)…”
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Ketolytic and glycolytic enzymatic expression profiles in malignant gliomas: implication for ketogenic diet therapy
Published in Nutrition & metabolism (05-07-2013)“…Recent studies in animal models, based on the hypothesis that malignant glioma cells are more dependent on glycolysis for energy generation, have shown…”
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Regulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic β-cells
Published in Biochemical pharmacology (01-01-2009)“…Using various biochemical, pharmacological and molecular biological approaches, we have recently reported regulatory roles for Rac1, a small G-protein, in…”
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Metabolic profiles of ketolysis and glycolysis in malignant gliomas: Possible predictors of response to ketogenic diet therapy
Published in Journal of clinical oncology (20-05-2013)“…Abstract only e13048 Background: The enzymatic differences in energy metabolism between normal brain tissues and malignant gliomas formed the basis for animal…”
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Impaired expression of ketone metabolizing enzymes in malignant gliomas: Implication for ketogenic diet therapy
Published in Journal of clinical oncology (20-05-2012)“…Abstract only 2056 Background: Malignant glial cells may have altered expression of mitochondrial enzymes that are key for deriving energy from ketones. The…”
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Energy restricted ketogenic diet (ERKD) treatment for advanced glioblastoma multiforme (GBM): Case report
Published in The FASEB journal (01-04-2013)“…Abstract only This study aimed to evaluate a 12 week ERKD protocol for advanced GBM. A 55 year old white male with progressive GBM was hospitalized to…”
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Treatment of advanced glioma with an energy restricted ketogenic diet: Case report and literature summary
Published in Journal of clinical oncology (20-05-2013)“…Abstract only e13047 Background: We initiated a pilot study to evaluate an energy restricted ketogenic diet (ERKD) as treatment for patients with glioblastoma…”
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Regulation of glucose- and mitochondrial fuel-induced insulin secretion by a cytosolic protein histidine phosphatase in pancreatic beta-cells
Published in American journal of physiology: endocrinology and metabolism (01-08-2010)“…We report localization of a cytosolic protein histidine phosphatase (PHP; approximately 16 kDa) in INS 832/13 cells, normal rat islets, and human islets…”
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Ambient Glucose Determines Glucose Transport In Human Retinal Pigment Epithelial Cells In Vitro
Published in Diabetes (New York, N.Y.) (01-05-1999)Get full text
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Upstream Stimulatory Factor Regulates Pdx-1 Gene Expression in Pancreatic BETA Cells
Published in Diabetes (New York, N.Y.) (01-05-1999)Get full text
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Dynamics of high energy nucleotide phosphoryl metabolism in intact HIT-T15 cells during glucose-induced insulin secretion
Published 01-01-1991“…To examine the dynamics of high energy nucleotide phosphoryl metabolism during glucose-induced insulin secretion, hydrolysis-reesterification reactions of high…”
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Dissertation