Search Results - "OLIVIUS, Petri"
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The Effects of Matrigel® on the Survival and Differentiation of a Human Neural Progenitor Dissociated Sphere Culture
Published in Anatomical Record Part A-discoveries in Molecular Cellular and Evolutionary Biology (01-03-2020)“…ABSTRACT We have previously developed an in vitro organotypic culture setting in order to investigate the performance of cellular substrates transplanted to…”
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Neuronal differentiation and extensive migration of human neural precursor cells following co-culture with rat auditory brainstem slices
Published in PloS one (07-03-2013)“…Congenital or acquired hearing loss is often associated with a progressive degeneration of the auditory nerve (AN) in the inner ear. The AN is composed of…”
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3
NGF stimulates extensive neurite outgrowth from implanted dorsal root ganglion neurons following transplantation into the adult rat inner ear
Published in Neurobiology of disease (01-02-2005)“…Neuronal tissue transplantation is a potential way to replace degenerated spiral ganglion neurons (SGNs) since these cells cannot regenerate in adult mammals…”
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Neurotrophic Factor Intervention Restores Auditory Function in Deafened Animals
Published in Proceedings of the National Academy of Sciences - PNAS (05-02-2002)“…A primary cause of deafness is damage of receptor cells in the inner ear. Clinically, it has been demonstrated that effective functionality can be provided by…”
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Central migration of neuronal tissue and embryonic stem cells following transplantation along the adult auditory nerve
Published in Brain research (05-11-2004)“…The regeneration of the auditory nerve remains a challenge in restoring hearing. An interesting approach would be to use a cell replacement therapy with the…”
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Functional evaluation of a cell replacement therapy in the inner ear
Published in Otology & neurotology (01-06-2009)“…Cell replacement therapy in the inner ear will contribute to the functional recovery of hearing loss. Cell replacement therapy is a potentially powerful…”
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7
Delayed neurotrophic treatment preserves nerve survival and electrophysiological responsiveness in neomycin-deafened guinea pigs
Published in Journal of neuroscience research (01-10-2004)“…Benefits of cochlear prostheses for the deaf are dependent on survival and excitability of the auditory nerve. Degeneration of deafferented auditory nerve…”
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Healing time, long-term result and effects of stem cell treatment in acute tympanic membrane perforation
Published in International journal of pediatric otorhinolaryngology (01-07-2007)“…Summary Objective The incidence of otitis media in children between the age of 2 and 6 years is well documented. Repeated attacks may cause acute and chronic…”
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A cell therapy approach to substitute neural elements in the inner ear
Published in Physiology & behavior (2007)“…Abstract Three different donor tissues were tested for their capacity to survive, integrate and differentiate in the adult inner ear. Surviving embryonic…”
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Survival of neuronal tissue following xenograft implantation into the adult rat inner ear
Published in Experimental neurology (2004)“…The poor regenerative capacity of the spiral ganglion neurons of the mammalian inner ear has initiated research on how to assist the functional recovery of the…”
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Survival, migration and differentiation of mouse tau-GFP embryonic stem cells transplanted into the rat auditory nerve
Published in Experimental neurology (01-06-2012)“…Stem cells have been investigated as treatment for a variety of diagnoses such as Parkinson's disease, Alzheimer's disease and spinal cord injuries. Here, we…”
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Effects of ROCK inhibitor Y27632 and EGFR inhibitor PD168393 on human neural precursors co-cultured with rat auditory brainstem explant
Published in Neuroscience (26-02-2015)“…Highlights • Attenuation of Rho/ROCK and EGFR signaling with Y27632 and PD168393 facilitates precursor cells neurite outgrowth. • Enhancement of migration and…”
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BDNF Increases Survival and Neuronal Differentiation of Human Neural Precursor Cells Cotransplanted with a Nanofiber Gel to the Auditory Nerve in a Rat Model of Neuronal Damage
Published in BioMed research international (01-01-2014)“…|Objectives. To study possible nerve regeneration of a damaged auditory nerve by the use of stem cell transplantation. Methods. We transplanted HNPCs to the…”
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14
Brain stem slice conditioned medium contains endogenous BDNF and GDNF that affect neural crest boundary cap cells in co-culture
Published in Brain research (30-05-2014)“…Abstract Conditioned medium (CM), made by collecting medium after a few days in cell culture and then re-using it to further stimulate other cells, is a known…”
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Brain stern slice conditioned medium contains endogenous BDNF and GDNF that affect neural crest boundary cap cells in co-culture
Published in Brain research (2014)“…Conditioned medium (CM), made by collecting medium after a few days in cell culture and then re-using it to further stimulate other cells, is a known…”
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16
Xenografted fetal dorsal root ganglion, embryonic stem cell and adult neural stem cell survival following implantation into the adult vestibulocochlear nerve
Published in Experimental neurology (2005)“…Sensorineural hearing loss is a disabling condition. In the post-embryonic and adult mammalian inner ear, the regeneration of auditory hair cells, spiral…”
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Morphological differentiation of tau–green fluorescent protein embryonic stem cells into neurons after co-culture with auditory brain stem slices
Published in Neuroscience (18-08-2009)“…Abstract Most types of congenital and acquired hearing loss are caused by loss of sensory hair cells in the inner ear and their respective afferent neurons…”
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Functional Stem Cell Integration into Neural Networks Assessed by Organotypic Slice Cultures
Published in Current protocols in stem cell biology (01-08-2017)“…Re-formation or preservation of functional, electrically active neural networks has been proffered as one of the goals of stem cell-mediated neural…”
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Olfactory ensheathing cells promote neurite outgrowth from co-cultured brain stem slice
Published in Experimental neurology (01-05-2011)“…Cell therapy aiming at the replacement of degenerated neurons is a very attractive approach. By using an established in vitro organotypic brain stem (BS) slice…”
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20
Viscoelastic and Histologic Properties in Scarred Rabbit Vocal Folds After Mesenchymal Stem Cell Injection
Published in The Laryngoscope (01-07-2006)“…Objective/Hypothesis: The aim of this study was to analyze the short‐term viscoelastic and histologic properties of scarred rabbit vocal folds after injection…”
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