Search Results - "OLEJNICKA, BEATA"

The Multifaceted Effects of Alpha1-Antitrypsin on Neutrophil Functions by Janciauskiene, Sabina, Wrenger, Sabine, Immenschuh, Stephan, Olejnicka, Beata, Greulich, Timm, Welte, Tobias, Chorostowska-Wynimko, Joanna

“…Neutrophils are the predominant immune cells in human blood possessing heterogeneity, plasticity and functional diversity. The activation and recruitment of…”
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Diagnostic and therapeutic value of human serpin family proteins by Janciauskiene, Sabina, Lechowicz, Urszula, Pelc, Magdalena, Olejnicka, Beata, Chorostowska-Wynimko, Joanna

“…SERPIN (serine proteinase inhibitors) is an acronym for the superfamily of structurally similar proteins found in animals, plants, bacteria, viruses, and…”
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Editorial: Acute phase proteins as biomarkers and therapeutics in acute and chronic inflammatory conditions by Stanke, Frauke, Janciauskiene, Sabina, Olejnicka, Beata

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Beneficial effects of alpha-1 antitrypsin therapy in a mouse model of colitis-associated colon cancer by Al-Omari, Mariam, Al-Omari, Tareq, Batainah, Nesreen, Al-Qauod, Khaled, Olejnicka, Beata, Janciauskiene, Sabina

“…It is widely accepted that chronic inflammatory bowel diseases significantly higher a risk for colorectal cancer development. Among different types of…”
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Plasma markers of COVID-19 severity: a pilot study by Beimdiek, Julia, Janciauskiene, Sabina, Wrenger, Sabine, Volland, Sonja, Rozy, Adriana, Fuge, Jan, Olejnicka, Beata, Pink, Isabell, Illig, Thomas, Popov, Alexander, Chorostowska, Joanna, Buettner, Falk F R, Welte, Tobias

“…SARS-CoV-2 infected patients show heterogeneous clinical presentations ranging from mild symptoms to severe respiratory failure and death. Consequently,…”
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Oxidative Stress Attenuates TLR3 Responsiveness and Impairs Anti-viral Mechanisms in Bronchial Epithelial Cells From COPD and Asthma Patients by Menzel, Mandy, Ramu, Sangeetha, Calvén, Jenny, Olejnicka, Beata, Sverrild, Asger, Porsbjerg, Celeste, Tufvesson, Ellen, Bjermer, Leif, Akbarshahi, Hamid, Uller, Lena

“…COPD and asthma exacerbations are commonly triggered by rhinovirus infection. Potentially promoting exacerbations, impaired anti-viral signaling and attenuated…”
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Boosted Pro-Inflammatory Activity in Human PBMCs by Lipopolysaccharide and SARS-CoV-2 Spike Protein Is Regulated by α-1 Antitrypsin by Tumpara, Srinu, Gründing, Anna R., Sivaraman, Kokilavani, Wrenger, Sabine, Olejnicka, Beata, Welte, Tobias, Wurm, Maria J., Pino, Paco, Kiseljak, Divor, Wurm, Florian M., Janciauskiene, Sabina

“…For the treatment of severe COVID-19, supplementation with human plasma-purified α-1 antitrypsin (AAT) to patients is currently considered. AAT inhibits host…”
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Human Bronchial Epithelial Cell Transcriptome Changes in Response to Serum from Patients with Different Status of Inflammation by Sivaraman, Kokilavani, Liu, Bin, Martinez-Delgado, Beatriz, Held, Julia, Büttner, Manuela, Illig, Thomas, Volland, Sonja, Gomez-Mariano, Gema, Jedicke, Nils, Yevsa, Tetyana, Welte, Tobias, DeLuca, David S., Wrenger, Sabine, Olejnicka, Beata, Janciauskiene, Sabina

“…Purpose To investigate the transcriptome of human bronchial epithelial cells (HBEC) in response to serum from patients with different degrees of inflammation…”
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A Novel Mouse Monoclonal Antibody C42 against C-Terminal Peptide of Alpha-1-Antitrypsin by Tumpara, Srinu, Korenbaum, Elena, Kühnel, Mark, Jonigk, Danny, Olejnicka, Beata, Davids, Michael, Welte, Tobias, Martinez-Delgado, Beatriz, Janciauskiene, Sabina

“…The C-terminal-fragments of alpha1-antitrypsin (AAT) have been identified and their diverse biological roles have been reported in vitro and in vivo. These…”
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The Relationship between Plasma Alpha-1-Antitrypsin Polymers and Lung or Liver Function in ZZ Alpha-1-Antitrypsin-Deficient Patients by Sark, Annelot D, Fromme, Malin, Olejnicka, Beata, Welte, Tobias, Strnad, Pavel, Janciauskiene, Sabina, Stolk, Jan

“…Alpha-1-Antitrypsin (AAT) is a protein of the SERPINA1 gene. A single amino acid mutation (Lys342Glu) results in an expression of misfolded Z-AAT protein,…”
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Indirect effect of alpha-1-antitrypsin on endotoxin-induced IL-1β secretion from human PBMCs by Janciauskiene, Sabina, Tumpara, Srinu, Schebb, Nils Helge, Buettner, Falk F. R., Mainka, Malwina, Sivaraman, Kokilavani, Immenschuh, Stephan, Grau, Veronika, Welte, Tobias, Olejnicka, Beata

“…Human alpha-1-antitrypsin (AAT) encoded by the SERPINA1 gene, is an acute phase glycoprotein that regulates inflammatory responses via both protease inhibitory…”
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Human PBMCs Form Lipid Droplets in Response to Spike Proteins by Sivaraman, Kokilavani, Pino, Paco, Raussin, Guillaume, Anchisi, Stephanie, Metayer, Charles, Dagany, Nicolas, Held, Julia, Wrenger, Sabine, Welte, Tobias, Wurm, Maria J, Wurm, Florian M, Olejnicka, Beata, Janciauskiene, Sabina

“…Intracellular lipid droplets (LDs) can accumulate in response to inflammation, metabolic stresses, and other physiological/pathological processes. Herein, we…”
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Plasma levels of α1-antitrypsin-derived C-terminal peptides in PiMM and PiZZ COPD patients by Börner, Friedemann R, Lechowicz, Urszula, Wrenger, Sabine, Martinez-Delgado, Beatriz, Olejnicka, Beata, Welte, Tobias, Chorostowska-Wynimko, Joanna, Kiehntopf, Michael, Janciauskiene, Sabina

“…Plasma levels of α1-antitrypsin-derived C-terminal peptides might be valid as novel biomarkers to predict and/or characterise exacerbations in PiMM and PiZZ…”
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Liquid-based cytology using cytorich red/tripath is diagnostically equivalent to conventional smears for bronchial washings and brushings and reduces the cost by Zendehrokh, Nooreldin, Olejnicka, Beata, Westman, Agneta, Dejmek, Annika

“…A split sample study was performed on 109 bronchial brushings and washings and evaluated from conventional slides (CS) and CytoRich Red/Tripath preparations…”
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Symptoms and quality of life in patients with chronic obstructive pulmonary disease treated with aclidinium in a real-life setting by Lange, Peter, Godtfredsen, Nina Skavlan, Olejnicka, Beata, Paradis, Bo-Anders, Curiac, Dan, Humerfelt, Sjur, Telg, Gunilla, Christensen, Helene Nordahl, Bitsch, Magnus Alexander, Andersen, Elisabeth Wreford, Bjermer, Leif

“…Chronic obstructive pulmonary disease (COPD) is a progressive disease with symptoms that can have a major impact on patients' physical health. The aim of this…”
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Gene and miRNA expression profiles in PBMCs from patients with severe and mild emphysema and PiZZ alpha I-antitrypsin deficiency by Esquinas, Cristina, Janciauskiene, Sabina, Gonzalo, Ricardo, de Xaxars, Gemma Mas, Olejnicka, Beata, Belmonte, Irene, Barrecheguren, Miriam, Rodriguez, Esther, Nuñez, Alexa, Rodriguez-Frias, Francisco, Miravitlles, Marc

“…Introduction: COPD has complex etiologies involving both genetic and environmental determinants. Among genetic determinants, the most recognized is a severe…”
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Plasma levels of α 1 -antitrypsin-derived C-terminal peptides in PiMM and PiZZ COPD patients by Börner, Friedemann R, Lechowicz, Urszula, Wrenger, Sabine, Martinez-Delgado, Beatriz, Olejnicka, Beata, Welte, Tobias, Chorostowska-Wynimko, Joanna, Kiehntopf, Michael, Janciauskiene, Sabina

“…https://bit.ly/3rNJeLd…”
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Multiple-valued and spectral approach to lossless compression of binary, gray scale and color biomedical images by Falkowski, B.J., Olejnicka, B.T.

“…In this paper, we propose a new method based on multiple-valued functions and spectral analysis for the lossless compression of binary, gray scale and color…”
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Plasminogen activator inhibitor-1 is elevated in patients with COPD independent of metabolic and cardiovascular function by Waschki, Benjamin, Watz, Henrik, Holz, Olaf, Magnussen, Helgo, Olejnicka, Beata, Welte, Tobias, Rabe, Klaus F, Janciauskiene, Sabina

“…Plasminogen activator inhibitor-1 (PAI-1), a major inhibitor of fibrinolysis, is associated with thrombosis, obesity, insulin resistance, dyslipidemia, and…”
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Gene and miRNA expression profiles in PBMCs from patients with severe and mild emphysema and PiZZ alpha1-antitrypsin deficiency by Esquinas, Cristina, Janciauskiene, Sabina, Gonzalo, Ricardo, Mas de Xaxars, Gemma, Olejnicka, Beata, Belmonte, Irene, Barrecheguren, Miriam, Rodriguez, Esther, Nuñez, Alexa, Rodriguez-Frias, Francisco, Miravitlles, Marc

“…COPD has complex etiologies involving both genetic and environmental determinants. Among genetic determinants, the most recognized is a severe PiZZ (Glu342Lys)…”
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