Search Results - "OLDENBURG, Anja"

Enriched domain detector: a program for detection of wide genomic enrichment domains robust against local variations by Lund, Eivind, Oldenburg, Anja R, Collas, Philippe

“…Nuclear lamins contact the genome at the nuclear periphery through large domains and are involved in chromatin organization. Among broad peak calling…”
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Chrom3D: three-dimensional genome modeling from Hi-C and nuclear lamin-genome contacts by Paulsen, Jonas, Sekelja, Monika, Oldenburg, Anja R, Barateau, Alice, Briand, Nolwenn, Delbarre, Erwan, Shah, Akshay, Sørensen, Anita L, Vigouroux, Corinne, Buendia, Brigitte, Collas, Philippe

“…Current three-dimensional (3D) genome modeling platforms are limited by their inability to account for radial placement of loci in the nucleus. We present…”
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Prepatterning of differentiation-driven nuclear lamin A/C-associated chromatin domains by GlcNAcylated histone H2B by Rønningen, Torunn, Shah, Akshay, Oldenburg, Anja R, Vekterud, Kristin, Delbarre, Erwan, Moskaug, Jan Øivind, Collas, Philippe

“…Dynamic interactions of nuclear lamins with chromatin through lamin-associated domains (LADs) contribute to spatial arrangement of the genome. Here, we provide…”
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Lamin A/C-promoter interactions specify chromatin state-dependent transcription outcomes by Lund, Eivind, Oldenburg, Anja R, Delbarre, Erwan, Freberg, Christel T, Duband-Goulet, Isabelle, Eskeland, Ragnhild, Buendia, Brigitte, Collas, Philippe

“…The nuclear lamina is implicated in the organization of the eukaryotic nucleus. Association of nuclear lamins with the genome occurs through large chromatin…”
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Closing the (nuclear) envelope on the genome: How nuclear lamins interact with promoters and modulate gene expression by Collas, Philippe, Lund, Eivind G., Oldenburg, Anja R.

“…The nuclear envelope shapes the functional organization of the nucleus. Increasing evidence indicates that one of its main components, the nuclear lamina,…”
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Local Delivery of Paclitaxel to Inhibit Restenosis during Angioplasty of the Leg by Tepe, Gunnar, Zeller, Thomas, Albrecht, Thomas, Heller, Stephan, Schwarzwälder, Uwe, Beregi, Jean-Paul, Claussen, M.D. Claus D, Oldenburg, Anja, Scheller, Bruno, Speck, Ulrich

“…In a randomized trial, 154 patients with femoropopliteal-artery disease who were undergoing angioplasty were assigned to treatment with a paclitaxel-coated…”
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Mapping Nuclear Lamin-Genome Interactions by Chromatin Immunoprecipitation of Nuclear Lamins by Oldenburg, Anja R, Collas, Philippe

“…The nuclear lamina is a meshwork of A- and B-type lamins which interact with chromatin and regulate many nuclear functions. Recent studies have reported the…”
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Deregulation of Fragile X-related protein 1 by the lipodystrophic lamin A p.R482W mutation elicits a myogenic gene expression program in preadipocytes by Oldenburg, Anja R, Delbarre, Erwan, Thiede, Bernd, Vigouroux, Corinne, Collas, Philippe

“…The nuclear lamina is implicated in the regulation of various nuclear functions. Several laminopathy-causing mutations in the LMNA gene, notably the p.R482W…”
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The p.R482W substitution in A-type lamins deregulates SREBP1 activity in Dunnigan-type familial partial lipodystrophy by Vadrot, Nathalie, Duband-Goulet, Isabelle, Cabet, Eva, Attanda, Wikayatou, Barateau, Alice, Vicart, Patrick, Gerbal, Fabien, Briand, Nolwenn, Vigouroux, Corinne, Oldenburg, Anja R, Lund, Eivind G, Collas, Philippe, Buendia, Brigitte

“…Nuclear lamins are involved in many cellular functions due to their ability to bind numerous partners including chromatin and transcription factors, and affect…”
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A hyper-dynamic nature of bivalent promoter states underlies coordinated developmental gene expression modules by Shah, Akshay, Oldenburg, Anja, Collas, Philippe

“…Chromatin remodeling is crucial for proper programing of developmental gene expression. Recent work provides a dynamic view of post-translational histone…”
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Profilin is required for viral morphogenesis, syncytium formation, and cell-specific stress fiber induction by respiratory syncytial virus by Bitko, Vira, Oldenburg, Anja, Garmon, Nicolle E, Barik, Sailen

“…Actin is required for the gene expression and morphogenesis of respiratory syncytial virus (RSV), a clinically important Pneumovirus of the Paramyxoviridae…”
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A lipodystrophy-causing lamin A mutant alters conformation and epigenetic regulation of the anti-adipogenic MIR335 locus by Oldenburg, Anja, Briand, Nolwenn, Sørensen, Anita L, Cahyani, Inswasti, Shah, Akshay, Moskaug, Jan Øivind, Collas, Philippe

“…Mutations in the ( ) gene-encoding nuclear LMNA cause laminopathies, which include partial lipodystrophies associated with metabolic syndromes. The…”
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Multiple cerebral aneurysms in factor VII deficiency by SCHILLING, Andreas M, HEIDENREICH, Jens O, OLDENBURG, Anja C, PIETILÄ, Terttu, STENDEL, Rüdiger, WOLF, Karl-Jürgen

“…A rare case of multiple cerebral aneurysms and factor VII deficiency is presented. The authors hypothesize a possible combined genetic defect similar to that…”
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The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks by Briand, Nolwenn, Guénantin, Anne-Claire, Jeziorowska, Dorota, Shah, Akshay, Mantecon, Matthieu, Capel, Emilie, Garcia, Marie, Oldenburg, Anja, Paulsen, Jonas, Hulot, Jean-Sebastien, Vigouroux, Corinne, Collas, Philippe

“…Abstract The p.R482W hotspot mutation in A-type nuclear lamins causes familial partial lipodystrophy of Dunnigan-type (FPLD2), a lipodystrophic syndrome…”
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Distinct features of lamin A-interacting chromatin domains mapped by ChIP-sequencing from sonicated or micrococcal nuclease-digested chromatin by Lund, Eivind G, Duband-Goulet, Isabelle, Oldenburg, Anja, Buendia, Brigitte, Collas, Philippe

“…The nuclear lamina has been shown to interact with the genome through lamina-associated domains (LADs). LADs have been identified by DamID, a proximity…”
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Characterisation and expression of a PP1 serine/threonine protein phosphatase (PfPP1) from the malaria parasite, Plasmodium falciparum: demonstration of its essential role using RNA interference by Kumar, Rajinder, Adams, Brian, Oldenburg, Anja, Musiyenko, Alla, Barik, Sailen

“…Reversible protein phosphorylation is relatively unexplored in the intracellular protozoa of the Apicomplexa family that includes the genus Plasmodium, to…”
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Potential value of contrast-enhanced intraoperative ultrasonography during partial hepatectomy for metastases : An essential investigation before resection? by LEEN, Edward, CECCOTTI, Piercarlo, HORGAN, Paul G, MOUG, Susan J, GLEN, Paul, MACQUARRIE, John, ANGERSON, Wilson J, ALBRECHT, Thomas, HOHMANN, Joachim, OLDENBURG, Anja, RITZ, Jorg Peter

“…The aim of the study was to assess the clinical value of contrast-enhanced intraoperative ultrasound (CE-IOUS) as a novel tool in the hepatic staging of…”
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Abstract 1329: Development of the first optimised “off the shelf” MAGE-A4 targeting TCR-NK cells for advancement into the clinic for the treatment of solid tumors by Vollmers, Sarah, Cieslar-Pobuda, Artur, Kmiecik, Justyna, Malachin, Giulia, Sætersmoen, Michelle L., Haugen, Frida Høsøien, Boieri, Margherita, Sandve, Maja, Clement, Dennis, Cardoso, Ines, Wanichawan, Pimthanya, Haugstøyl, Martha E., Oldenburg, Anja, Christ, Liliane, Oberoi, Pranav, Mora-Velandia, Luz, Holm, Anders, Hassan, Namir J., Gauthy, Emilie, Ino, Julia, Pollmann, Sylvie, Weigand, Luise U.

“…T cell receptor (TCR)-T based therapies, such as MAGE-A4 TCR-T cells, have shown compelling data demonstrating effective infiltration into and targeting of…”
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Hepatic Transit Time Analysis Using Contrast-Enhanced Ultrasound with BR1: A Prospective Study Comparing Patients with Liver Metastases from Colorectal Cancer with Healthy Volunteers by Hohmann, Joachim, Müller, Christine, Oldenburg, Anja, Skrok, Jan, Frericks, Bernd B, Wolf, Karl-Jürgen, Albrecht, Thomas

“…Abstract We prospectively compared hepatic transit time (HTT) measurements in subjects with liver metastases from colorectal cancer (group a) and healthy…”
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Imaging of paediatric splenic injury with contrast-enhanced ultrasonography by Oldenburg, Anja, Hohmann, Joachim, Skrok, Jan, Albrecht, Thomas

“…We report two children who sustained traumatic parenchymal splenic injury and were monitored with contrast-enhanced ultrasound (CEUS). In both cases,…”
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