Search Results - "OLBRYT, Magdalena"

Biological Factors behind Melanoma Response to Immune Checkpoint Inhibitors by Olbryt, Magdalena, Rajczykowski, Marcin, Widłak, Wiesława

“…Modern immunotherapy together with targeted therapy has revolutionized the treatment of advanced melanoma. Inhibition of immune checkpoints significantly…”
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Genetic Profiling of Advanced Melanoma: Candidate Mutations for Predicting Sensitivity and Resistance to Targeted Therapy by Olbryt, Magdalena, Pigłowski, Wojciech, Rajczykowski, Marcin, Pfeifer, Aleksandra, Student, Sebastian, Fiszer-Kierzkowska, Anna

“…Background Molecularly targeted therapy has revolutionized the treatment of advanced melanoma. However, despite its high efficiency, a majority of patients…”
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Global gene expression profiling in three tumor cell lines subjected to experimental cycling and chronic hypoxia by Olbryt, Magdalena, Habryka, Anna, Student, Sebastian, Jarząb, Michał, Tyszkiewicz, Tomasz, Lisowska, Katarzyna Marta

“…Hypoxia is one of the most important features of the tumor microenvironment, exerting an adverse effect on tumor aggressiveness and patient prognosis. Two…”
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Establishment and Characterization of the Novel High-Grade Serous Ovarian Cancer Cell Line OVPA8 by Tudrej, Patrycja, Olbryt, Magdalena, Zembala-Nożyńska, Ewa, Kujawa, Katarzyna A, Cortez, Alexander J, Fiszer-Kierzkowska, Anna, Pigłowski, Wojciech, Nikiel, Barbara, Głowala-Kosińska, Magdalena, Bartkowska-Chrobok, Aleksandra, Smagur, Andrzej, Fidyk, Wojciech, Lisowska, Katarzyna M

“…High-grade serous ovarian carcinoma (HGSOC) is the most frequent histological type of ovarian cancer and the one with worst prognosis. Unfortunately, the…”
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NGS Analysis of Liquid Biopsy (LB) and Formalin-Fixed Paraffin-Embedded (FFPE) Melanoma Samples Using Oncomine™ Pan-Cancer Cell-Free Assay by Olbryt, Magdalena, Rajczykowski, Marcin, Bal, Wiesław, Fiszer-Kierzkowska, Anna, Cortez, Alexander Jorge, Mazur, Magdalena, Suwiński, Rafał, Widłak, Wiesława

“…Next-generation sequencing (NGS) in liquid biopsies may contribute to the diagnosis, monitoring, and personalized therapy of cancer through the real-time…”
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Potential Biomarkers of Skin Melanoma Resistance to Targeted Therapy-Present State and Perspectives by Olbryt, Magdalena

“…Melanoma is the most aggressive skin cancer, the number of which is increasing worldwide every year. It is completely curable in its early stage and fatal when…”
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Molecular background of skin melanoma development and progression: therapeutic implications by Olbryt, Magdalena

“…Melanoma is the most aggressive skin cancer with an increasing number of cases worldwide and curable mostly in its early stage. The improvement in patients'…”
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Melanoma genomics – will we go beyond BRAF in clinics? by Mirek, Justyna, Bal, Wiesław, Olbryt, Magdalena

“…In the era of next-generation sequencing, the genetic background of cancer, including melanoma, appears to be thoroughly established. However, evaluating the…”
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Role of tumor microenvironment in the formation and progression of skin melanoma by Olbryt, Magdalena

“…Melanoma develops from melanocytes localized mainly in skin, to a lesser extent in uvea and mucosal tissue. It is one of the most aggressive tumors, resistant…”
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A receptor kinase gene of the LysM type is involved in legumeperception of rhizobial signals by Stougaard, Jens, Madsen, Esben Bjørn, Madsen, Lene Heegaard, Radutoiu, Simona, Olbryt, Magdalena, Rakwalska, Magdalena, Szczyglowski, Krzysztof, Sato, Shusei, Kaneko, Takakazu, Tabata, Satoshi, Sandal, Niels

“…Plants belonging to the legume family develop nitrogen-fixing root nodules in symbiosis with bacteria commonly known as rhizobia. The legume host encodes all…”
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An Increase in HSF1 Expression Directs Human Mammary Epithelial Cells toward a Mesenchymal Phenotype by Vydra, Natalia, Toma-Jonik, Agnieszka, Janus, Patryk, Mrowiec, Katarzyna, Stokowy, Tomasz, Głowala-Kosińska, Magdalena, Sojka, Damian Robert, Olbryt, Magdalena, Widłak, Wiesława

“…HSF1 is a well-known heat shock protein expression regulator in response to stress. It also regulates processes important for growth, development or…”
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Prognostic significance of Epstein‐Barr virus viral load in patients with T1‐T2 nasopharyngeal cancer by Mazurek, Agnieszka M., Wygoda, Andrzej, Rutkowski, Tomasz, Olbryt, Magdalena, Pietrowska, Monika, Celejewska, Agata, Składowski, Krzysztof, Widłak, Piotr

“…Nasopharyngeal cancer (NPC) is highly prevalent in southern Chinese populations but it is rare in most parts of the world. A few studies were performed in…”
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The putative oncogene, CRNDE, is a negative prognostic factor in ovarian cancer patients by Szafron, Lukasz Michal, Balcerak, Anna, Grzybowska, Ewa Anna, Pienkowska-Grela, Barbara, Podgorska, Agnieszka, Zub, Renata, Olbryt, Magdalena, Pamula-Pilat, Jolanta, Lisowska, Katarzyna M, Grzybowska, Ewa, Rubel, Tymon, Dansonka-Mieszkowska, Agnieszka, Konopka, Bozena, Kulesza, Magdalena, Lukasik, Martyna, Kupryjanczyk, Jolanta

“…The CRNDE gene seems to play an oncogenic role in cancers, though its exact function remains unknown. Here, we tried to assess its usefulness as a molecular…”
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Unsupervised analysis reveals two molecular subgroups of serous ovarian cancer with distinct gene expression profiles and survival by Lisowska, Katarzyna M., Olbryt, Magdalena, Student, Sebastian, Kujawa, Katarzyna A., Cortez, Alexander J., Simek, Krzysztof, Dansonka-Mieszkowska, Agnieszka, Rzepecka, Iwona K., Tudrej, Patrycja, Kupryjańczyk, Jolanta

“…Purpose Ovarian cancer is typically diagnosed at late stages, and thus, patients’ prognosis is poor. Improvement in treatment outcomes depends, at least…”
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Evaluation of the Role of ITGBL1 in Ovarian Cancer by Cortez, Alexander Jorge, Kujawa, Katarzyna Aleksandra, Wilk, Agata Małgorzata, Sojka, Damian Robert, Syrkis, Joanna Patrycja, Olbryt, Magdalena, Lisowska, Katarzyna Marta

“…In our previous microarray study we identified two subgroups of high-grade serous ovarian cancers with distinct gene expression and survival. Among…”
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A receptor kinase gene of the LysM type is involved in legume perception of rhizobial signals by MADSEN, Esben Bjørn, MADSEN, Lene Heegaard, STOUGAARD, Jens, RADUTOIU, Simona, OLBRYT, Magdalena, RAKWALSKA, Magdalena, SZOZYGLOWSKI, Krzysztof, SATO, Shusel, KANEKO, Takakazu, TABATA, Satoshi, SANDAL, Nlels

“…Plants belonging to the legume family develop nitrogen-fixing root nodules in symbiosis with bacteria commonly known as rhizobia. The legume host encodes all…”
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Bis-anthracycline WP760 abrogates melanoma cell growth by transcription inhibition, p53 activation and IGF1R downregulation by Olbryt, Magdalena, Rusin, Aleksandra, Fokt, Izabela, Habryka, Anna, Tudrej, Patrycja, Student, Sebastian, Sochanik, Aleksander, Zieliński, Rafał, Priebe, Waldemar

“…Summary Anthracycline chemotherapeutics, e.g. doxorubicin and daunorubicin, are active against a broad spectrum of cancers. Their cytotoxicity is mainly…”
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Gene expression analysis in ovarian cancer - faults and hints from DNA microarray study by Lisowska, Katarzyna Marta, Olbryt, Magdalena, Dudaladava, Volha, Pamuła-Piłat, Jolanta, Kujawa, Katarzyna, Grzybowska, Ewa, Jarząb, Michał, Student, Sebastian, Rzepecka, Iwona Krystyna, Jarząb, Barbara, Kupryjańczyk, Jolanta

“…The introduction of microarray techniques to cancer research brought great expectations for finding biomarkers that would improve patients' treatment; however,…”
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Impact of heat shock transcription factor 1 on global gene expression profiles in cells which induce either cytoprotective or pro-apoptotic response following hyperthermia by Kus-Liśkiewicz, Małgorzata, Polańska, Joanna, Korfanty, Joanna, Olbryt, Magdalena, Vydra, Natalia, Toma, Agnieszka, Widłak, Wiesława

“…Elevated temperatures induce activation of the heat shock transcription factor 1 (HSF1) which in somatic cells leads to heat shock proteins synthesis and…”
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Melanoma-associated genes, MXI1, FN1, and NME1, are hypoxia responsive in murine and human melanoma cells by Olbryt, Magdalena, Habryka, Anna, Tyszkiewicz, Tomasz, Rusin, Aleksandra, Cichoń, Tomasz, Jarząb, Michał, Krawczyk, Zdzisław

“…Hypoxia can influence aggressiveness of melanoma by inducing specific gene expression profiles. In our previous microarray study, we identified more than 430…”
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