Search Results - "OLBINA, Gordana"

Immunoassay for human serum hepcidin by Ganz, Tomas, Olbina, Gordana, Girelli, Domenico, Nemeth, Elizabeta, Westerman, Mark

“…We developed and validated the first serum enzyme-linked immunosorbent assay for hepcidin, the principal iron-regulatory hormone that has been very difficult…”
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A Novel Hypoxia-Inducible Factor−Prolyl Hydroxylase Inhibitor (GSK1278863) for Anemia in CKD: A 28-Day, Phase 2A Randomized Trial by Brigandi, Richard A., MD, PhD, Johnson, Brendan, PhD, Oei, Coreen, PhD, Westerman, Mark, PhD, Olbina, Gordana, PhD, de Zoysa, Janak, MBChB, Roger, Simon D., MD, Sahay, Manisha, MD, DNB, Cross, Nicholas, MBChB, MM, PhD, McMahon, Lawrence, MD, Guptha, Veerabhadra, MD, Smolyarchuk, Elena A., MD, Singh, Narinder, MD, Russ, Steven F., MPH, Kumar, Sanjay, PhD

“…Background Anemia associated with chronic kidney disease (CKD) often requires treatment with recombinant human erythropoietin (EPO). Hypoxia-inducible…”
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Hepcidin—A Potential Novel Biomarker for Iron Status in Chronic Kidney Disease by Zaritsky, Joshua, Young, Brian, Wang, He-Jing, Westerman, Mark, Olbina, Gordana, Nemeth, Elizabeta, Ganz, Tomas, Rivera, Seth, Nissenson, Allen R, Salusky, Isidro B

“…Hepcidin is a key regulator of iron homeostasis, but its study in the setting of chronic kidney disease (CKD) has been hampered by the lack of validated serum…”
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Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization by KROOT, Joyce J. C, KEMNA, Erwin H. J. M, TOMOSUGI, Naohisa, TSELEPIS, Chris, WARD, Douglas G, GANZ, Tomas, HENDRIKS, Jan C. M, SWINKELS, Dorine W, BANSAL, Sukhvinder S, BUSBRIDGE, Mark, CAMPOSTRINI, Natascia, GIRELLI, Domenico, HIDER, Robert C, KOLIARAKI, Vasiliki, MAMALAKI, Avgi, OLBINA, Gordana

“…The recently discovered iron regulatory peptide hormone hepcidin holds promise as a novel biomarker in iron metabolism disorders. To date, various mass…”
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Effect of calcitriol on serum hepcidin in individuals with chronic kidney disease: a randomized controlled trial by Panwar, Bhupesh, McCann, Diane, Olbina, Gordana, Westerman, Mark, Gutiérrez, Orlando M

“…Anemia is highly prevalent in chronic kidney disease (CKD). Elevated hepcidin concentrations are an important mediator of disordered iron metabolism, a key…”
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Hepcidin level predicts hemoglobin concentration in individuals undergoing repeated phlebotomy by Mast, Alan E, Schlumpf, Karen S, Wright, David J, Johnson, Bryce, Glynn, Simone A, Busch, Michael P, Olbina, Gordana, Westerman, Mark, Nemeth, Elizabeta, Ganz, Tomas

“…Dietary iron absorption is regulated by hepcidin, an iron regulatory protein produced by the liver. Hepcidin production is regulated by iron stores,…”
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Testosterone Suppresses Hepcidin in Men: A Potential Mechanism for Testosterone-Induced Erythrocytosis by Bachman, Eric, Feng, Rui, Travison, Thomas, Li, Michelle, Olbina, Gordana, Ostland, Vaughn, Ulloor, Jagadish, Zhang, Anqi, Basaria, Shehzad, Ganz, Tomas, Westerman, Mark, Bhasin, Shalender

“…Context: The mechanisms by which testosterone increases hemoglobin and hematocrit are unknown. Objective: The aim was to test the hypothesis that…”
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Toward Worldwide Hepcidin Assay Harmonization: Identification of a Commutable Secondary Reference Material by van der Vorm, Lisa N, Hendriks, Jan C M, Laarakkers, Coby M, Klaver, Siem, Armitage, Andrew E, Bamberg, Alison, Geurts-Moespot, Anneke J, Girelli, Domenico, Herkert, Matthias, Itkonen, Outi, Konrad, Robert J, Tomosugi, Naohisa, Westerman, Mark, Bansal, Sukhvinder S, Campostrini, Natascia, Drakesmith, Hal, Fillet, Marianne, Olbina, Gordana, Pasricha, Sant-Rayn, Pitts, Kelly R, Sloan, John H, Tagliaro, Franco, Weykamp, Cas W, Swinkels, Dorine W

“…Absolute plasma hepcidin concentrations measured by various procedures differ substantially, complicating interpretation of results and rendering reference…”
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A Novel Sandwich ELISA to Quantify Erythroferrone in Mouse Serum by Gutschow, Patrick, Han, Huiling, Olbina, Gordana, Westerman, Keith, Westerman, Eileen, Ruiz Martinez, Marc, Ginzburg, Yelena, Nemeth, Elizabeta, Ganz, Tomas, Ostland, Vaughn

“…Erythroferrone (ERFE) is a hormone produced by erythroblasts in response to erythropoietin. ERFE acts as a regulator of hepcidin expression during stress…”
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Validation of the Intrinsic Hepcidin IDxTM Test, an LDT for Clinical Hepcidin Assessment by Gutschow, Patrick, Westerman, Keith, Han, Huiling, Ostland, Vaughn, Olbina, Gordana, Paxton, William, Westerman, Mark

“…▪ Introduction: Hepcidin is the principal regulator of iron absorption and iron recycling, and is required to provide iron for erythropoiesis. Hepcidin is a…”
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Normalizing hepcidin predicts TMPRSS6 mutation status in patients with chronic iron deficiency by Heeney, Matthew M., Guo, Dongjing, De Falco, Luigia, Campagna, Dean R., Olbina, Gordana, Kao, Paige P.-C., Schmitz-Abe, Klaus, Rahimov, Fedik, Gutschow, Patrick, Westerman, Keith, Ostland, Vaughn, Jackson, Tracy, Klaassen, Robert J., Markianos, Kyriacos, Finberg, Karin E., Iolascon, Achille, Westerman, Mark, London, Wendy B., Fleming, Mark D.

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Provisional standardization of hepcidin assays: creating a traceability chain with a primary reference material, candidate reference method and a commutable secondary reference material by Diepeveen, Laura E, Laarakkers, Coby M M, Martos, Gustavo, Pawlak, Marta E, Uğuz, Fatih F, Verberne, Kim E S A, van Swelm, Rachel P L, Klaver, Siem, de Haan, Anton F J, Pitts, Kelly R, Bansal, Sukhvinder S, Abbas, Ioana M, Fillet, Marianne, Lefebvre, Thibaud, Geurts-Moespot, Anneke J, Girelli, Domenico, Castagna, Annalisa, Herkert, Matthias, Itkonen, Outi, Olbina, Gordana, Tomosugi, Naohisa, Westerman, Mark E, Delatour, Vincent, Weykamp, Cas W, Swinkels, Dorine W

“…Background Hepcidin concentrations measured by various methods differ considerably, complicating interpretation. Here, a previously identified plasma-based…”
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Increased serum hepcidin levels during treatment with deferasirox in iron‐overloaded patients with myelodysplastic syndrome by Ghoti, Hussam, Fibach, Eitan, Westerman, Mark, Gordana, Olbina, Ganz, Tomas, Rachmilewitz, Eliezer A.

“…Summary Hepcidin is a major regulator of iron metabolism. We evaluated changes in serum hepcidin during 3 months of therapy with the iron‐chelator deferasirox…”
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Serum hepcidin is significantly associated with iron absorption from food and supplemental sources in healthy young women by Young, Melissa F, Glahn, Raymond P, Ariza-Nieto, Magnolia, Inglis, Jeremy, Olbina, Gordana, Westerman, Mark, O'Brien, Kimberly O

“…BACKGROUND: Hepcidin is a key regulator of iron homeostasis, but to date no studies have examined the effect of hepcidin on iron absorption in humans…”
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Clinical Immunoassay for Human Hepcidin Predicts Iron Deficiency in First-Time Blood Donors by Gutschow, Patrick, Han, Huiling, Olbina, Gordana, Westerman, Keith, Nemeth, Elizabeta, Ganz, Tomas, Copeland, Karen, Westerman, Mark, Ostland, Vaughn

“…Serum markers currently used as indicators of iron status have clinical limitations. Hepcidin, a key regulator of iron homeostasis, is reduced in iron…”
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Iron absorption in dysmetabolic iron overload syndrome is decreased and correlates with increased plasma hepcidin by Ruivard, Marc, Lainé, Fabrice, Ganz, Tomas, Olbina, Gordana, Westerman, Mark, Nemeth, Elizabeta, Rambeau, Mathieu, Mazur, André, Gerbaud, Laurent, Tournilhac, Valérie, Abergel, Armand, Philippe, Pierre, Deugnier, Yves, Coudray, Charles

“…Background/Aims The dysmetabolic iron overload syndrome (DIOS) is a common disorder but its origin remains unclear. Methods A case-control study was conducted…”
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A Novel Dual Monoclonal Sandwich ELISA for Human Erythroferrone by Han, Huiling, Westerman, Keith, Ostland, Vaughn, Gutschow, Patrick, Olbina, Gordana, da Silva Guimarães, Jacqueline, Cominal, Juçara Gastaldi, de Souza, Ana Maria, Silva Pinto, Ana Cristina, Rivella, Stefano, Ginzburg, Yelena, Fleming, Mark D., Westerman, Mark

“…Erythroferrone (ERFE) is a hormone produced by erythroblasts in the bone marrow in response to erythropoietin (EPO). Recent animal studies have shown that…”
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Mutations in the second extracellular region of connexin 43 prevent localization to the plasma membrane, but do not affect its ability to suppress cell growth by OLBINA, Gordana, ECKHART, Walter

“…Connexin 43 (Cx43), the most widely expressed gap junction protein, has a role in regulation of cell growth. In this study, we demonstrate that the point…”
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Altered erythropoiesis and iron metabolism in carriers of thalassemia by Guimarães, Jacqueline S., Cominal, Juçara G., Silva-Pinto, Ana Cristina, Olbina, Gordana, Ginzburg, Yelena Z., Nandi, Vijay, Westerman, Mark, Rivella, Stefano, de Souza, Ana Maria

“…The thalassemia syndromes (α‐ and β‐thalassemia) are the most common and frequent disorders associated with ineffective erythropoiesis. Imbalance of α‐ or…”
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Short-Term Effects of Blood Transfusions on Hepcidin in Preterm Infants by Lorenz, Laila, Müller, Katharina F, Poets, Christian F, Peter, Andreas, Olbina, Gordana, Westerman, Mark, Franz, Axel R

“…Hepcidin, a key regulatory peptide hormone in iron homeostasis, may in future serve as a non-invasive iron status parameter for monitoring iron supplementation…”
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