Search Results - "OKUNO, S"

An open-label, multicenter, phase II study of bevacizumab for the treatment of angiosarcoma and epithelioid hemangioendotheliomas by Agulnik, M., Yarber, J.L., Okuno, S.H., von Mehren, M., Jovanovic, B.D., Brockstein, B.E., Evens, A.M., Benjamin, R.S.

“…To determine efficacy and safety of bevacizumab, a recombinant humanized antibody against vascular endothelial growth factor (VEGF), in the treatment of…”
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Dupilumab improves both histaminergic and touch‐evoked itch sensitization (hyperknesis) in atopic dermatitis: a pilot study by Hashimoto, T., Okuno, S., Okuzawa, M., Satoh, T.

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Observation of Spectral Structures in the Flux of Cosmic-Ray Protons from 50 GeV to 60 TeV with the Calorimetric Electron Telescope on the International Space Station by Adriani, O., Akaike, Y., Asano, K., Asaoka, Y., Berti, E., Bigongiari, G., Binns, W. R., Bongi, M., Brogi, P., Bruno, A., Buckley, J. H., Cannady, N., Castellini, G., Checchia, C., Cherry, M. L., Collazuol, G., Ebisawa, K., Ficklin, A. W., Fuke, H., Gonzi, S., Guzik, T. G., Hams, T., Hibino, K., Ichimura, M., Ioka, K., Ishizaki, W., Israel, M. H., Kasahara, K., Kataoka, J., Kataoka, R., Katayose, Y., Kato, C., Kawanaka, N., Kawakubo, Y., Kobayashi, K., Kohri, K., Krawczynski, H. S., Krizmanic, J. F., Maestro, P., Marrocchesi, P. S., Messineo, A. M., Mitchell, J. W., Miyake, S., Moiseev, A. A., Mori, M., Mori, N., Motz, H. M., Munakata, K., Nakahira, S., Nishimura, J., de Nolfo, G. A., Okuno, S., Ormes, J. F., Ozawa, S., Pacini, L., Papini, P., Rauch, B. F., Ricciarini, S. B., Sakai, K., Sakamoto, T., Sasaki, M., Shimizu, Y., Shiomi, A., Spillantini, P., Stolzi, F., Sugita, S., Sulaj, A., Takita, M., Tamura, T., Terasawa, T., Torii, S., Tsunesada, Y., Uchihori, Y., Vannuccini, E., Wefel, J. P., Yamaoka, K., Yanagita, S., Yoshida, A., Yoshida, K., Zober, W. V.

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Direct Measurement of the Cosmic-Ray Carbon and Oxygen Spectra from 10 GeV/n to 2.2 TeV/n with the Calorimetric Electron Telescope on the International Space Station by Adriani, O., Akaike, Y., Asano, K., Asaoka, Y., Bagliesi, M. G., Berti, E., Bigongiari, G., Binns, W. R., Bongi, M., Brogi, P., Bruno, A., Buckley, J. H., Cannady, N., Castellini, G., Checchia, C., Cherry, M. L., Collazuol, G., Ebisawa, K., Fuke, H., Gonzi, S., Guzik, T. G., Hams, T., Hibino, K., Ichimura, M., Ioka, K., Ishizaki, W., Israel, M. H., Kasahara, K., Kataoka, J., Kataoka, R., Katayose, Y., Kato, C., Kawanaka, N., Kawakubo, Y., Kobayashi, K., Kohri, K., Krawczynski, H. S., Krizmanic, J. F., Link, J., Maestro, P., Marrocchesi, P. S., Messineo, A. M., Mitchell, J. W., Miyake, S., Moiseev, A. A., Mori, M., Mori, N., Motz, H. M., Munakata, K., Nakahira, S., Nishimura, J., Nolfo, G. A. De, Okuno, S., Ormes, J. F., Ospina, N., Ozawa, S., Pacini, L., Palma, F., Papini, P., Rauch, B. F., Ricciarini, S. B., Sakai, K., Sakamoto, T., Sasaki, M., Shimizu, Y., Shiomi, A., Sparvoli, R., Spillantini, P., Stolzi, F., Sugita, S., Suh, J. E., Sulaj, A., Takita, M., Tamura, T., Terasawa, T., Torii, S., Tsunesada, Y., Uchihori, Y., Vannuccini, E., Wefel, J. P., Yamaoka, K., Yanagita, S., Yoshida, A., Yoshida, K.

“…In this paper, we present the measurement of the energy spectra of carbon and oxygen in cosmic rays based on observations with the Calorimetric Electron…”
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Phase II study of the HSP90-inhibitor BIIB021 in gastrointestinal stromal tumors by Dickson, M.A., Okuno, S.H., Keohan, M.L., Maki, R.G., D'Adamo, D.R., Akhurst, T.J., Antonescu, C.R., Schwartz, G.K.

“…HSP90 inhibition leads to proteosomal degradation of activated KIT and has in vitro activity against gastrointestinal stromal tumors (GIST). BIIB021 is an oral…”
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Measurement of the Iron Spectrum in Cosmic Rays from 10 GeV/n to 2.0 TeV/n with the Calorimetric Electron Telescope on the International Space Station by Akaike, Y, Asano, K, Asaoka, Y, Berti, E, Bigongiari, G, Binns, W R, Bongi, M, Brogi, P, Bruno, Alessandro, Buckley, J H, Cannady, Nicholas Wade, Castellini, G, Checchia, C, Cherry, M L, Collazuol, G, Ebisawa, K, Fuke, H, Gonzi, S, Guzik, T Gregory, Hams, Thomas, Hibino, K, Ichimura, M, Ioka, K, Ishizaki, W, Israel, M H, Kasahara, K, Kataoka, J, Kataoka, R, Katayose, Y, Kato, C, Kawanaka, N, Kawakubo, Y, Kobayashi, K, Kohri, K, Krizmanic, J F, Link, J T, Mitchell, J W, Moiseev, A A, Nolfo, G A De, Sakai, K, Sasaki, M

“…The Calorimetric Electron Telescope (CALET), in operation on the International Space Station since 2015, collected a large sample of cosmic-ray iron over a…”
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Cosmic-Ray Boron Flux Measured from 8.4  GeV/n to 3.8  TeV/n with the Calorimetric Electron Telescope on the International Space Station by Adriani, O, Akaike, Y, Asano, K, Asaoka, Y, Berti, E, Bigongiari, G, Binns, W R, Bongi, M, Brogi, P, Bruno, A, Buckley, J H, Cannady, N, Castellini, G, Checchia, C, Cherry, M L, Collazuol, G, de Nolfo, G A, Ebisawa, K, Ficklin, A W, Fuke, H, Gonzi, S, Guzik, T G, Hams, T, Hibino, K, Ichimura, M, Ioka, K, Ishizaki, W, Israel, M H, Kasahara, K, Kataoka, J, Kataoka, R, Katayose, Y, Kato, C, Kawanaka, N, Kawakubo, Y, Kobayashi, K, Kohri, K, Krawczynski, H S, Krizmanic, J F, Maestro, P, Marrocchesi, P S, Messineo, A M, Mitchell, J W, Miyake, S, Moiseev, A A, Mori, M, Mori, N, Motz, H M, Munakata, K, Nakahira, S, Nishimura, J, Okuno, S, Ormes, J F, Ozawa, S, Pacini, L, Papini, P, Rauch, B F, Ricciarini, S B, Sakai, K, Sakamoto, T, Sasaki, M, Shimizu, Y, Shiomi, A, Spillantini, P, Stolzi, F, Sugita, S, Sulaj, A, Takita, M, Tamura, T, Terasawa, T, Torii, S, Tsunesada, Y, Uchihori, Y, Vannuccini, E, Wefel, J P, Yamaoka, K, Yanagita, S, Yoshida, A, Yoshida, K, Zober, W V

“…We present the measurement of the energy dependence of the boron flux in cosmic rays and its ratio to the carbon flux in an energy interval from 8.4  GeV/n to…”
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Direct Measurement of the Cosmic-Ray Helium Spectrum from 40 GeV to 250 TeV with the Calorimetric Electron Telescope on the International Space Station by Adriani, O, Akaike, Y, Asano, K, Asaoka, Y, Bertin, E, Bigongiari, G, Binns, W R, Bongi, M, Brogi, P, Bruno, A, Buckley, J H, Cannady, N, Castellini, G, Checchia, C, Cherry, M L, Collazuol, G, Nolfo, G A de, Ebisawa, K, Ficklin, A W, Fuke, H, Gonzi, S, Guzik, T G, Hams, T, Hibino, K, Ichimura, M, Ioka, K, Ishizaki, W, Israel, M H, Kasahara, K, Kataoka, J, Kataoka, R, Katayose, Y, Kato, C, Kawanaka, N, Mitchell, J W, Krizmanic, J F

“…We present the results of a direct measurement of the cosmic-ray helium spectrum with the CALET instrument in operation on the International Space Station…”
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Increased undercarboxylated osteocalcin/intact osteocalcin ratio in patients undergoing hemodialysis by Nagata, Y., Inaba, M., Imanishi, Y., Okazaki, H., Yamada, S., Mori, K., Shoji, S., Koyama, H., Okuno, S.

“…Summary Serum undercarboxylated osteocalcin (ucOC)/intact osteocalcin (iOC) ratio increased >1.0 in the patients undergoing hemodialysis, particularly in those…”
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Geriatric Nutritional Risk Index, a simplified nutritional screening index, is a significant predictor of mortality in chronic dialysis patients by Kobayashi, Ikue, Ishimura, Eiji, Kato, Yoko, Okuno, Senji, Yamamoto, Tadashi, Yamakawa, Tomoyuki, Mori, Katsuhito, Inaba, Masaaki, Nishizawa, Yoshiki

“…Background. Malnutrition is a common complication in haemodialysis patients. Recently, the Geriatric Nutritional Risk Index (GNRI) has been reported as a…”
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Direct Measurement of the Nickel Spectrum in Cosmic Rays in the Energy Range from 8.8  GeV/n to 240  GeV/n with CALET on the International Space Station by Adriani, O, Akaike, Y, Asano, K, Asaoka, Y, Berti, E, Bigongiari, G, Binns, W R, Bongi, M, Brogi, P, Bruno, A, Buckley, J H, Cannady, N, Castellini, G, Checchia, C, Cherry, M L, Collazuol, G, Ebisawa, K, Ficklin, A W, Fuke, H, Gonzi, S, Guzik, T G, Hams, T, Hibino, K, Ichimura, M, Ioka, K, Ishizaki, W, Israel, M H, Kasahara, K, Kataoka, J, Kataoka, R, Katayose, Y, Kato, C, Kawanaka, N, Kawakubo, Y, Kobayashi, K, Kohri, K, Krawczynski, H S, Krizmanic, J F, Maestro, P, Marrocchesi, P S, Messineo, A M, Mitchell, J W, Miyake, S, Moiseev, A A, Mori, M, Mori, N, Motz, H M, Munakata, K, Nakahira, S, Nishimura, J, de Nolfo, G A, Okuno, S, Ormes, J F, Ospina, N, Ozawa, S, Pacini, L, Papini, P, Rauch, B F, Ricciarini, S B, Sakai, K, Sakamoto, T, Sasaki, M, Shimizu, Y, Shiomi, A, Spillantini, P, Stolzi, F, Sugita, S, Sulaj, A, Takita, M, Tamura, T, Terasawa, T, Torii, S, Tsunesada, Y, Uchihori, Y, Vannuccini, E, Wefel, J P, Yamaoka, K, Yanagita, S, Yoshida, A, Yoshida, K, Zober, W V

“…The relative abundance of cosmic ray nickel nuclei with respect to iron is by far larger than for all other transiron elements; therefore it provides a…”
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Direct Measurement of the Spectral Structure of Cosmic-Ray Electrons+Positrons in the Tev Region With Calet on the International Space Station by Adriani, O., Akaike, Y., Asano, K., Asaoka, Y., Berti, E., Bigongiari, G., Binns, W. R., Bongi, M., Brogi, P., Bruno, A., Buckley, J. H., Cannady, N., Castellini, G., Checchia, C., Cherry, M. L., Collazuol, G., Nolfo, G. A. de, Ebisawa, K., Ficklin, A. W., Fuke, H., Gonzi, S., Guzik, T. G., Hams, T., Hibino, K., Ichimura, M., Ioka, Kunihito, Ishizaki, W., Israel, M. H., Kasahara, K., Kataoka, J., Kataoka, R., Katayose, Y., Kato, C., Kawanaka, N., Kawakubo, Y., Krizmanic, J. F., Mitchell, J.W.

“…Detailed measurements of the spectral structure of cosmic-ray electrons and positrons from 10.6 GeV to 7.5 TeV are presented from over 7 years of observations…”
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Deposition of silicon-doped diamond-like carbon films by plasma-enhanced chemical vapor deposition using an intermittent supply of organosilane by Nakazawa, H., Kamata, R., Okuno, S.

“…We have deposited Si-doped DLC (Si-DLC) multilayer films by plasma-enhanced chemical vapor deposition (PECVD) using an intermittent supply of monomethylsilane…”
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Erratum: Charge-Sign Dependent Cosmic-Ray Modulation Observed with the Calorimetric Electron Telescope on the International Space Station [Phys. Rev. Lett. 130 , 211001 (2023)] by Adriani, O., Akaike, Y., Asano, K., Asaoka, Y., Berti, E., Bigongiari, G., Binns, W. R., Bongi, M., Brogi, P., Bruno, A., Buckley, J. H., Cannady, N., Castellini, G., Checchia, C., Cherry, M. L., Collazuol, G., de Nolfo, G. A., Ebisawa, K., Ficklin, A. W., Fuke, H., Gonzi, S., Guzik, T. G., Hams, T., Hibino, K., Ichimura, M., Ioka, K., Ishizaki, W., Israel, M. H., Kasahara, K., Kataoka, J., Kataoka, R., Katayose, Y., Kato, C., Kawanaka, N., Kawakubo, Y., Kobayashi, K., Kohri, K., Krawczynski, H. S., Krizmanic, J. F., Maestro, P., Marrocchesi, P. S., Messineo, A. M., Mitchell, J. W., Miyake, S., Moiseev, A. A., Mori, M., Mori, N., Motz, H. M., Munakata, K., Nakahira, S., Nishimura, J., Okuno, S., Ormes, J. F., Ozawa, S., Pacini, L., Papini, P., Rauch, B. F., Ricciarini, S. B., Sakai, K., Sakamoto, T., Sasaki, M., Shimizu, Y., Shiomi, A., Spillantini, P., Stolzi, F., Sugita, S., Sulaj, A., Takita, M., Tamura, T., Terasawa, T., Torii, S., Tsunesada, Y., Uchihori, Y., Vannuccini, E., Wefel, J. P., Yamaoka, K., Yanagita, S., Yoshida, A., Yoshida, K., Zober, W. V.

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Multicenter, open-label phase II study of daily oral regorafenib for chemotherapy-refractory, metastatic and locally advanced angiosarcoma by Agulnik, M., van Tine, B.A., Attia, S., Rademaker, A., Milhem, M., Okuno, S.H.

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Phase I-II trial of ONYX-015 in combination with MAP chemotherapy in patients with advanced sarcomas by GALANIS, E, OKUNO, S. H, RANDLEV, B, WANG, Q, FREEMAN, S, RUBIN, J, NASCIMENTO, A. G, LEWIS, B. D, LEE, R. A, OLIVEIRA, A. M, SLOAN, J. A, ATHERTON, P, EDMONSON, J. H, ERLICHMAN, C

“…ONYX-015 is a provisionally replication competent adenovirus with oncolytic activity in cells with malfunctioning p53. Sarcomas represent a rational target for…”
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Significant inverse relationship between serum undercarboxylated osteocalcin and glycemic control in maintenance hemodialysis patients by Okuno, S., Ishimura, E., Tsuboniwa, N., Norimine, K., Yamakawa, K., Yamakawa, T., Shoji, S., Mori, K., Nishizawa, Y., Inaba, M.

“…Summary Increased levels of serum undercarboxylated osteocalcin, which were associated with bone metabolism markers, correlated inversely with indices of…”
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A phase II study of tivozanib in patients with metastatic and nonresectable soft-tissue sarcomas by Agulnik, M., Costa, R.L.B., Milhem, M., Rademaker, A.W., Prunder, B.C., Daniels, D., Rhodes, B.T., Humphreys, C., Abbinanti, S., Nye, L., Cehic, R., Polish, A., Vintilescu, C., McFarland, T., Skubitz, K., Robinson, S., Okuno, S., Van Tine, B.A.

“…Soft tissue sarcomas (STSs) overexpress vascular endothelial growth factors (VEGF) and VEGF-receptors (VEGFR) activation have been associated with tumor…”
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Role of fibroblast growth factor-23 in peripheral vascular calcification in non-diabetic and diabetic hemodialysis patients by INABA, M, OKUNO, S, IMANISHI, Y, YAMADA, S, SHIOI, A, YAMAKAWA, T, ISHIMURA, E, NISHIZAWA, Y

“…Fibroblast growth factor (FGF) 23 is a recently identified circulating factor that regulates phosphate (Pi) metabolism. Since the derangement of Pi control is…”
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Significant association between the presence of peripheral vascular calcification and lower serum magnesium in hemodialysis patients by Ishimura, E, Okuno, S, Kitatani, K, Tsuchida, T, Yamakawa, T, Shioi, A, Inaba, M, Nishizawa, Y

“…Vascular calcification, which significantly increases cardiovascular and other causes of mortality, is highly prevalent in hemodialysis patients. The aim of…”
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