Search Results - "OKUDA, Keiji"

Chemical Endoplasmic Reticulum Chaperone Alleviates Doxorubicin-Induced Cardiac Dysfunction by Fu, Hai Ying, Sanada, Shoji, Matsuzaki, Takashi, Liao, Yulin, Okuda, Keiji, Yamato, Masaki, Tsuchida, Shota, Araki, Ryo, Asano, Yoshihiro, Asanuma, Hiroshi, Asakura, Masanori, French, Brent A, Sakata, Yasushi, Kitakaze, Masafumi, Minamino, Tetsuo

“…RATIONALE:Doxorubicin is an effective chemotherapeutic agent for cancer, but its use is often limited by cardiotoxicity. Doxorubicin causes endoplasmic…”
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Ablation of C/EBP Homologous Protein Attenuates Endoplasmic Reticulum-Mediated Apoptosis and Cardiac Dysfunction Induced by Pressure Overload by HAI YING FU, OKADA, Ken-Ichiro, ASANUMA, Hiroshi, ASAKURA, Masanori, TAKASHIMA, Seiji, KOMURO, Issei, KITAKAZE, Masafumi, MINAMINO, Tetsuo, YULIN LIAO, TSUKAMOTO, Osamu, ISOMURA, Tadashi, ASAI, Mitsutoshi, SAWADA, Tamaki, OKUDA, Keiji, ASANO, Yoshihiro, SANADA, Shoji

“…Apoptosis may contribute to the development of heart failure, but the role of apoptotic signaling initiated by the endoplasmic reticulum in this condition has…”
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International Pellet Watch: Global monitoring of persistent organic pollutants (POPs) in coastal waters. 1. Initial phase data on PCBs, DDTs, and HCHs by Ogata, Yuko, Takada, Hideshige, Mizukawa, Kaoruko, Hirai, Hisashi, Iwasa, Satoru, Endo, Satoshi, Mato, Yukie, Saha, Mahua, Okuda, Keiji, Nakashima, Arisa, Murakami, Michio, Zurcher, Nico, Booyatumanondo, Ruchaya, Zakaria, Mohamad Pauzi, Dung, Le Quang, Gordon, Miriam, Miguez, Carlos, Suzuki, Satoru, Moore, Charles, Karapanagioti, Hrissi K., Weerts, Steven, McClurg, Tim, Burres, Erick, Smith, Wally, Velkenburg, Michael Van, Lang, Judith Selby, Lang, Richard C., Laursen, Duane, Danner, Brenda, Stewardson, Nickol, Thompson, Richard C.

“…Samples of polyethylene pellets were collected at 30 beaches from 17 countries and analyzed for organochlorine compounds. PCB concentrations in the pellets…”
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Concentration of polychlorinated biphenyls (PCBs) in beached resin pellets: Variability among individual particles and regional differences by Endo, Satoshi, Takizawa, Reiko, Okuda, Keiji, Takada, Hideshige, Chiba, Kazuhiro, Kanehiro, Haruyuki, Ogi, Haruo, Yamashita, Rei, Date, Takeshi

“…Concentrations of polychlorinated biphenyls (PCBs) in beached resin pellets were examined to reveal variability between individual particles and differences…”
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Comparison of Usefulness of Sodium Bicarbonate Versus Sodium Chloride to Prevent Contrast-Induced Nephropathy in Patients Undergoing an Emergent Coronary Procedure by Masuda, Masaharu, MD, Yamada, Takahisa, MD, PhD, Mine, Takanao, MD, PhD, Morita, Takashi, MD, PhD, Tamaki, Shunsuke, MD, Tsukamoto, Yasumasa, MD, Okuda, Keiji, MD, Iwasaki, Yuusuke, MD, Hori, Masatsugo, MD, PhD, Fukunami, Masatake, MD, PhD

“…In the case of an emergency coronary procedure where the risk of contrast-induced nephropathy is especially high, there are few reliable methods to attenuate…”
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Spatial Distribution and Temporal Trend of Anthropogenic Organic Compounds Derived from the 2011 East Japan Earthquake by Mizukawa, Kaoruko, Hirai, Yasuko, Sakakibara, Hiroyuki, Endo, Satoshi, Okuda, Keiji, Takada, Hideshige, Murakami-Sugihara, Naoko, Shirai, Kotaro, Ogawa, Hiroshi

“…The tsunami caused by the Great East Japan Earthquake on March 11, 2011 disturbed coastal environments in the eastern Tohoku region in Japan. Numerous…”
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Maxacalcitol (22-Oxacalcitriol (OCT)) Retards Progression of Left Ventricular Hypertrophy with Renal Dysfunction Through Inhibition of Calcineurin-NFAT Activity by Inoue, Kazunori, Matsui, Isao, Hamano, Takayuki, Okuda, Keiji, Tsukamoto, Yasumasa, Matsumoto, Ayumi, Shimada, Karin, Yasuda, Seiichi, Katsuma, Yusuke, Takabatake, Yoshitsugu, Tanaka, Masaru, Tanaka, Noriko, Mano, Toshiaki, Minamino, Tetsuo, Sakata, Yasushi, Isaka, Yoshitaka

“…Purpose Left ventricular hypertrophy (LVH) is a cardiovascular complication highly prevalent in patients with chronic kidney disease (CKD). Previous studies…”
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Targeted Therapy for Acute Autoimmune Myocarditis with Nano-Sized Liposomal FK506 in Rats by Okuda, Keiji, Fu, Hai Ying, Matsuzaki, Takashi, Araki, Ryo, Tsuchida, Shota, Thanikachalam, Punniyakoti V, Fukuta, Tatsuya, Asai, Tomohiro, Yamato, Masaki, Sanada, Shoji, Asanuma, Hiroshi, Asano, Yoshihiro, Asakura, Masanori, Hanawa, Haruo, Hao, Hiroyuki, Oku, Naoto, Takashima, Seiji, Kitakaze, Masafumi, Sakata, Yasushi, Minamino, Tetsuo

“…Immunosuppressive agents are used for the treatment of immune-mediated myocarditis; however, the need to develop a more effective therapeutic approach remains…”
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Anti-HB-EGF Antibody-Mediated Delivery of siRNA to Atherosclerotic Lesions in Mice by Tsuchida, Shota, Matsuzaki, Takashi, Yamato, Masaki, Okuda, Keiji, Fu, Hai Ying, Araki, Ryo, Sanada, Shoji, Asanuma, Hiroshi, Asano, Yoshihiro, Asakura, Masanori, Hao, Hiroyuki, Takashima, Seiji, Kitakaze, Masafumi, Sakata, Yasushi, Mekada, Eisuke, Minamino, Tetsuo

“…For atherosclerotic cardiovascular diseases (ACD), gene therapy may be a potential therapeutic strategy; however, lack of effective and safe methods for gene…”
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X-box binding protein 1 regulates brain natriuretic peptide through a novel AP1/CRE-like element in cardiomyocytes by Sawada, Tamaki, Minamino, Tetsuo, Fu, Hai Ying, Asai, Mitsutoshi, Okuda, Keiji, Isomura, Tadashi, Yamazaki, Satoru, Asano, Yoshihiro, Okada, Ken-ichiro, Tsukamoto, Osamu, Sanada, Shoji, Asanuma, Hiroshi, Asakura, Masanori, Takashima, Seiji, Kitakaze, Masafumi, Komuro, Issei

“…Abstract The unfolded protein response (UPR) is triggered to assist protein folding when endoplasmic reticulum (ER) function is impaired. Recent studies…”
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Liposomal Amiodarone Augments Anti-arrhythmic Effects and Reduces Hemodynamic Adverse Effects in an Ischemia/Reperfusion Rat Model by Takahama, Hiroyuki, Shigematsu, Hirokazu, Asai, Tomohiro, Matsuzaki, Takashi, Sanada, Shoji, Fu, Hai Ying, Okuda, Keiji, Yamato, Masaki, Asanuma, Hiroshi, Asano, Yoshihiro, Asakura, Masanori, Oku, Naoto, Komuro, Issei, Kitakaze, Masafumi, Minamino, Tetsuo

“…Purpose Although amiodarone is recognized as the most effective anti-arrhythmic drug available, it has negative hemodynamic effects. Nano-sized liposomes can…”
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Long-term effect of atorvastatin on neurohumoral activation and cardiac function in patients with chronic heart failure: A prospective randomized controlled study by Yamada, Takahisa, MD, Node, Koichi, MD, Mine, Takanao, MD, Morita, Takashi, MD, Kioka, Hidetaka, MD, Tsukamoto, Yasumasa, MD, Tamaki, Shunsuke, MD, Masuda, Masaharu, MD, Okuda, Keiji, MD, Fukunami, Masatake, MD

“…Background Statins have pleiotropic effects, such as improvement in endothelial function and antiinflammatory, antiproliferative, and antioxidative effects,…”
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RNA Aptamer Binds Heparin-Binding Epidermal Growth Factor-Like Growth Factor with High Affinity and Specificity and Neutralizes Its Activity by Masaki Yamato, Takashi Matsuzaki, Ryo Araki, Shota Tsuchida, Keiji Okuda, Hai Ying Fu, Shoji Sanada, Hiroshi Asanuma, Yoshihiro Asano, Masanori Asakura, Hiroomi Torii, Kentaro Noi, Hirotsugu Ogi, Ryo Iwamoto, Eisuke Mekada, Seiji Takashima, Masafumi Kitakaze, Yasushi Sakata, Tetsuo Minamino

“…Background: Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the EGF family and is involved in various diseases including…”
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Sodium Bicarbonate Improves Long-Term Clinical Outcomes Compared With Sodium Chloride in Patients With Chronic Kidney Disease Undergoing an Emergent Coronary Procedure by Masuda, Masaharu, Yamada, Takahisa, Okuyama, Yuji, Morita, Takashi, Sanada, Shoji, Furukawa, Yoshio, Tsukamoto, Yasumasa, Okuda, Keiji, Iwasaki, Yuusuke, Yasui, Taku, Fukunami, Masatake

“…Background Contrast-induced nephropathy is associated with increased in-hospital and long-term adverse clinical outcomes. Methods and Results To investigate…”
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Development of a novel one-step production system for injectable liposomes under GMP by Araki, Ryo, Matsuzaki, Takashi, Nakamura, Ayumi, Nakatani, Daisaku, Sanada, Shoji, Fu, Hai Ying, Okuda, Keiji, Yamato, Masaki, Tsuchida, Shota, Sakata, Yasushi, Minamino, Tetsuo

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Cardiac Iodine-123 Metaiodobenzylguanidine Imaging Predicts Sudden Cardiac Death Independently of Left Ventricular Ejection Fraction in Patients With Chronic Heart Failure and Left Ventricular Systolic Dysfunction by Tamaki, Shunsuke, MD, Yamada, Takahisa, MD, Okuyama, Yuji, MD, Morita, Takashi, MD, Sanada, Shoji, MD, Tsukamoto, Yasumasa, MD, Masuda, Masaharu, MD, Okuda, Keiji, MD, Iwasaki, Yusuke, MD, Yasui, Taku, MD, Hori, Masatsugu, MD, Fukunami, Masatake, MD

“…Objectives We prospectively compared the predictive value of cardiac iodine-123 metaiodobenzylguanidine (MIBG) imaging for sudden cardiac death (SCD) with that…”
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The large intestine: inflammatory bowel disease (IBD) by Okuda, Keiji

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The large intestine: examination methods and colon tumors by Koshizuka, Shinji, Okuda, Keiji

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Ablation of IL-33 gene exacerbate myocardial remodeling in mice with heart failure induced by mechanical stress by Veeraveedu, Punniyakoti T., Sanada, Shoji, Okuda, Keiji, Fu, Hai Ying, Matsuzaki, Takashi, Araki, Ryo, Yamato, Masaki, Yasuda, Koubun, Sakata, Yasushi, Yoshimoto, Tomohiro, Minamino, Tetsuo

“…[Display omitted] ST2 is one of the interleukin (IL)-1 receptor family members comprising of membrane-bound (ST2L) and soluble (sST2) isoforms. Clinical trials…”
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Cardiac Iodine-123 Metaiodobenzylguanidine Imaging Predicts Sudden Cardiac Death Independently of Left Ventricular Ejection Fraction in Patients With Chronic Heart Failure and Left Ventricular Systolic Dysfunction : Results From a Comparative Study With Signal-Averaged Electrocardiogram, Heart Rate Variability, and QT Dispersion by TAMAKI, Shunsuke, YAMADA, Takahisa, HORI, Masatsugu, FUKUNAMI, Masatake, OKUYAMA, Yuji, MORITA, Takashi, SANADA, Shoji, TSUKAMOTO, Yasumasa, MASUDA, Masaharu, OKUDA, Keiji, IWASAKI, Yusuke, YASUI, Taku

“…We prospectively compared the predictive value of cardiac iodine-123 metaiodobenzylguanidine (MIBG) imaging for sudden cardiac death (SCD) with that of the…”
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