Search Results - "OKAZAWA, Hidehiko"

Molecular imaging for mitochondrial metabolism and oxidative stress in mitochondrial diseases and neurodegenerative disorders by Ikawa, Masamichi, Okazawa, Hidehiko, Yoneda, Makoto

“…Increasing evidence from pathological and biochemical investigations suggests that mitochondrial metabolic impairment and oxidative stress play a crucial role…”
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Quantification of brain oxygen extraction and metabolism with [15O]-gas PET: A technical review in the era of PET/MRI by Fan, Audrey P., An, Hongyu, Moradi, Farshad, Rosenberg, Jarrett, Ishii, Yosuke, Nariai, Tadashi, Okazawa, Hidehiko, Zaharchuk, Greg

“…Oxygen extraction fraction (OEF) and the cerebral metabolic rate of oxygen (CMRO2) are key cerebral physiological parameters to identify at-risk…”
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PET/MRI multimodality imaging to evaluate changes in glymphatic system function and biomarkers of Alzheimer’s disease by Okazawa, Hidehiko, Nogami, Munenobu, Ishida, Shota, Makino, Akira, Mori, Tetsuya, Kiyono, Yasushi, Ikawa, Masamichi

“…The glymphatic system is considered to play a pivotal role in the clearance of disease-causing proteins in neurodegenerative diseases. This study employed MR…”
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Prognostic value of 18F-FDG PET in uterine cervical cancer patients with stage IIICr allocated by imaging by Isaji, Yuzu, Tsuyoshi, Hideaki, Tsujikawa, Tetsuya, Orisaka, Makoto, Okazawa, Hidehiko, Yoshida, Yoshio

“…The effect on survival of radiographic lymph node metastasis in uterine cervical cancer patients is more important than before, even though its prognostic…”
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Sex Differences in White Matter Pathways Related to Language Ability by Jung, Minyoung, Mody, Maria, Fujioka, Toru, Kimura, Yukari, Okazawa, Hidehiko, Kosaka, Hirotaka

“…Evidence from functional imaging studies points to a role for gender in language ability. However, recent studies suggest that sex differences in the neural…”
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Elucidation of the relationship between sensory processing and white matter using diffusion tensor imaging tractography in young adults by Shiotsu, Daichi, Jung, Minyoung, Habata, Kaie, Kamiya, Taku, Omori, Ichiro M., Okazawa, Hidehiko, Kosaka, Hirotaka

“…Sensory processing and behaviors are altered during the development of connectivity between the sensory cortices and multiple brain regions in an…”
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PET Imaging for Oxidative Stress in Neurodegenerative Disorders Associated with Mitochondrial Dysfunction by Ikawa, Masamichi, Okazawa, Hidehiko, Nakamoto, Yasunari, Yoneda, Makoto

“…Oxidative stress based on mitochondrial dysfunction is assumed to be the principal molecular mechanism for the pathogenesis of many neurodegenerative…”
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Intrinsic brain activity associated with eye gaze during mother–child interaction by Kuboshita, Ryo, Fujisawa, Takashi X., Makita, Kai, Kasaba, Ryoko, Okazawa, Hidehiko, Tomoda, Akemi

“…Mother–child interactions impact child social development and psychological health. This study focused on eye-gaze interactions, especially eye contact as…”
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Relationship between sensory characteristics and cortical thickness/volume in autism spectrum disorders by Habata, Kaie, Cheong, Yongjeon, Kamiya, Taku, Shiotsu, Daichi, Omori, Ichiro M., Okazawa, Hidehiko, Jung, Minyoung, Kosaka, Hirotaka

“…Individuals with autism spectrum disorders (ASDs) exhibit atypical sensory characteristics, impaired social skills, deficits in verbal and nonverbal…”
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Sex Differences in the Default Mode Network with Regard to Autism Spectrum Traits: A Resting State fMRI Study by Jung, Minyoung, Mody, Maria, Saito, Daisuke N, Tomoda, Akemi, Okazawa, Hidehiko, Wada, Yuji, Kosaka, Hirotaka

“…Autism spectrum traits exist on a continuum and are more common in males than in females, but the basis for this sex difference is unclear. To this end, the…”
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Diagnostic value of [18F]FDG PET/MRI for staging in patients with ovarian cancer by Tsuyoshi, Hideaki, Tsujikawa, Tetsuya, Yamada, Shizuka, Okazawa, Hidehiko, Yoshida, Yoshio

“…Purpose To evaluate the diagnostic potential of PET/MRI with 2-[ 18 F]fluoro-2-deoxy- d -glucose ([ 18 F]FDG) in ovarian cancer. Materials and methods…”
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Arterial Transit Time Mapping Obtained by Pulsed Continuous 3D ASL Imaging with Multiple Post-Label Delay Acquisitions: Comparative Study with PET-CBF in Patients with Chronic Occlusive Cerebrovascular Disease by Tsujikawa, Tetsuya, Kimura, Hirohiko, Matsuda, Tsuyoshi, Fujiwara, Yasuhiro, Isozaki, Makoto, Kikuta, Ken-Ichiro, Okazawa, Hidehiko

“…Arterial transit time (ATT) is most crucial for measuring absolute cerebral blood flow (CBF) by arterial spin labeling (ASL), a noninvasive magnetic resonance…”
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The effects of epigenetic age and its acceleration on surface area, cortical thickness, and volume in young adults by Cheong, Yongjeon, Nishitani, Shota, Yu, Jinyoung, Habata, Kaie, Kamiya, Taku, Shiotsu, Daichi, Omori, Ichiro M, Okazawa, Hidehiko, Tomoda, Akemi, Kosaka, Hirotaka, Jung, Minyoung

“…DNA methylation age has been used in recent studies as an epigenetic marker of accelerated cellular aging, whose contribution to the brain structural changes…”
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High efficacy of particle beam therapies against tumors under hypoxia and prediction of the early stage treatment effect using 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography by Makino, Akira, Kume, Kyo, Mori, Tetsuya, Tsujikawa, Tetsuya, Asai, Tatsuya, Okazawa, Hidehiko, Kiyono, Yasushi

“…Objective Compared with radiation therapy using photon beams, particle therapies, especially those using carbons, show a high relative biological effectiveness…”
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Brain structures and functional connectivity in neglected children with no other types of maltreatment by Kawata, Natasha Y.S., Nishitani, Shota, Yao, Akiko, Takiguchi, Shinichiro, Mizuno, Yoshifumi, Mizushima, Sakae, Makita, Kai, Hamamura, Shoko, Saito, Daisuke N., Okazawa, Hidehiko, Fujisawa, Takashi X., Tomoda, Akemi

“…•Exposure to neglect makes the brain atypical at structural and functional levels.•Larger ACC was the one of structural atypicality.•Increased FC between the…”
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Development of Low Molecular Weight Ligands for Integrin αvβ3 by Makino, Akira, Ueda, Masahiro, Uematsu, Yoshitaka, Ohora, Takuya, Ohtani, Takayuki, Miyagawa, Shinobu, Fujibayashi, Yasuhisa, Okazawa, Hidehiko, Tokunaga, Yuji, Kiyono, Yasushi

“…We designed and synthesized non-peptide organic molecular ligands for integrin αvβ3. Candidate ligands featured amidino analog and carboxy groups as binding…”
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Development of Right-hemispheric Dominance of Inferior Parietal Lobule in Proprioceptive Illusion Task by Naito, Eiichi, Morita, Tomoyo, Saito, Daisuke N, Ban, Midori, Shimada, Koji, Okamoto, Yuko, Kosaka, Hirotaka, Okazawa, Hidehiko, Asada, Minoru

“…Functional lateralization can be an indicator of brain maturation. We have consistently shown that, in the adult brain, proprioceptive processing of muscle…”
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Integrated [18F]FDG PET/MRI demonstrates the iron-related bone-marrow physiology by Tsujikawa, Tetsuya, Oikawa, Hiroshi, Tasaki, Toshiki, Hosono, Naoko, Tsuyoshi, Hideaki, Rahman, Mahmudur G. M., Yoshida, Yoshio, Yamauchi, Takahiro, Kimura, Hirohiko, Okazawa, Hidehiko

“…We identified predictors for bone-marrow [ 18 F]FDG uptake and MR signals among complete blood count, C-reactive protein (CRP), and anthropometric factors, and…”
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PET Imaging of Estrogen Receptors for Gynecological Tumors by Tsujikawa, Tetsuya, Makino, Akira, Mori, Tetsuya, Tsuyoshi, Hideaki, Kiyono, Yasushi, Yoshida, Yoshio, Okazawa, Hidehiko

“…In the past few decades, PET with 18F-FDG has been used for the diagnosis of gynecological malignancies and is considered to be superior to conventional…”
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Region-based analysis of sensory processing using diffusion tensor imaging by Nakagawa, Kai, Cheong, Yongjeon, Lee, Seonkyoung, Habata, Kaie, Kamiya, Taku, Shiotsu, Daichi, Omori, Ichiro M, Okazawa, Hidehiko, Kosaka, Hirotaka, Jung, Minyoung

“…The caudate nucleus has been thought to be involved in the control of motor commands by the cerebrum, and recent studies suggest that it may play a role in the…”
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