Search Results - "OHTSUKA, Takao"
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Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-09-2017)“…The management of intraductal papillary mucinous neoplasm (IPMN) continues to evolve. In particular, the indications for resection of branch duct IPMN have…”
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Necroptosis in pancreatic cancer promotes cancer cell migration and invasion by release of CXCL5
Published in PloS one (30-01-2020)“…Necroptosis is a form of programmed cell death that is accompanied by release of intracellular contents, and reportedly contributes to various diseases. Here,…”
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Minimally invasive surgery for pancreatic cancer
Published in Surgery today (Tokyo, Japan) (01-02-2021)“…Pancreatic cancer is the most lethal malignancy of the digestive organs. Although pancreatic resection is essential to radically cure this refractory disease,…”
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Molecular pathogenesis of breast cancer: impact of miR-99a-5p and miR-99a-3p regulation on oncogenic genes
Published in Journal of human genetics (01-05-2021)“…Our recent research has revealed that passenger strands of certain microRNAs (miRNAs) function as tumor-suppressive miRNAs in cancer cells, e.g., miR-101-5p,…”
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Evidence-based clinical practice guidelines for chronic pancreatitis 2021
Published in Journal of gastroenterology (01-10-2022)“…Background Chronic pancreatitis (CP) is defined according to the recently proposed mechanistic definition as a pathological fibro-inflammatory syndrome of the…”
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Pancreatic Juice Exosomal MicroRNAs as Biomarkers for Detection of Pancreatic Ductal Adenocarcinoma
Published in Annals of surgical oncology (01-07-2019)“…Background Pancreatic ductal adenocarcinoma (PDAC) is a lethal neoplasm because of difficulties in early detection. Several studies have recently suggested…”
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Multicenter study of early pancreatic cancer in Japan
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-01-2018)“…The diagnosis of early-stage pancreatic ductal adenocarcinoma (PDAC) is still challenging. We conducted a multicenter study to clarify the clinical features of…”
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The novel driver gene ASAP2 is a potential druggable target in pancreatic cancer
Published in Cancer science (01-04-2021)“…Targeting mutated oncogenes is an effective approach for treating cancer. The 4 main driver genes of pancreatic ductal adenocarcinoma (PDAC) are KRAS, TP53,…”
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Comparison of Surgical Outcomes Between Radical Antegrade Modular Pancreatosplenectomy (RAMPS) and Standard Retrograde Pancreatosplenectomy (SPRS) for Left-Sided Pancreatic Cancer
Published in World journal of surgery (01-09-2016)“…Background Radical antegrade modular pancreatosplenectomy (RAMPS) is a modification of standard retrograde pancreatosplenectomy (SRPS) used to achieve the…”
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Attempts to prevent postoperative pancreatic fistula after distal pancreatectomy
Published in Surgery today (Tokyo, Japan) (01-04-2017)“…Postoperative pancreatic fistula (POPF) is the most frequent and serious complication after distal pancreatectomy (DP) and often leads to other postoperative…”
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Neutrophil extracellular traps promote liver micrometastasis in pancreatic ductal adenocarcinoma via the activation of cancer‑associated fibroblasts
Published in International journal of oncology (01-02-2020)“…Cancer-associated fibroblasts (CAFs) promote the progression of pancreatic ductal adenocarcinoma (PDAC) via tumor-stromal interactions. Neutrophil…”
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Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c‐Met system via hypoxia inducible factor‐1 in pancreatic cancer
Published in Cancer science (01-07-2008)“…Hepatocyte growth facor activator (HGFA) is a serine protease that converts hepatocyte growth factor (HGF) into its active form. Our previous study…”
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Recurrence patterns after surgical resection of intraductal papillary mucinous neoplasm (IPMN) of the pancreas; a multicenter, retrospective study of 1074 IPMN patients by the Japan Pancreas Society
Published in Journal of gastroenterology (01-01-2020)“…Background Although there are numerous reports focusing on surgical indication for intraductal papillary mucinous neoplasm (IPMN), the recurrence patterns…”
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Inhibition of ERK1/2 in cancer-associated pancreatic stellate cells suppresses cancer-stromal interaction and metastasis
Published in Journal of experimental & clinical cancer research (27-05-2019)“…Extracellular signal-regulated kinases (ERKs) have been related to multiple cancers, including breast cancer, hepatocellular cancer, lung cancer and colorectal…”
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Clinical significance of circulating tumor cells in the response to trastuzumab for HER2-negative metastatic gastric cancer
Published in Cancer chemotherapy and pharmacology (01-06-2021)“…Purpose The prognosis of metastatic gastric cancer has improved due to trastuzumab in patients with HER2 positive. Circulating tumor cells (CTCs) have been…”
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Analysis of lymph node metastasis in pancreatic neuroendocrine tumors (PNETs) based on the tumor size and hormonal production
Published in Journal of gastroenterology (01-06-2012)“…Background Because of the rarity and variety of pancreatic neuroendocrine tumors (PNETs), there have been few reports regarding the indication for lymph node…”
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Anatomical study of the inferior mesenteric vein using three-dimensional computed tomography angiography in laparoscopy-assisted surgery for left-sided colorectal cancer
Published in Surgery today (Tokyo, Japan) (01-10-2021)“…Purpose To investigate the drainage patterns of the inferior mesenteric vein (IMV) and measure the distance from the root of the inferior mesenteric artery…”
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Conversion surgery for hepatocellular carcinoma with portal vein tumor thrombus after successful atezolizumab plus bevacizumab therapy: a case report
Published in World journal of surgical oncology (12-07-2022)“…Abstract Background The treatment of hepatocellular carcinoma (HCC) requires diverse and multidisciplinary approaches. In recent years, new agents with good…”
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Effectiveness of Adjuvant Therapy in Patients with Pancreatic Cancer Who Underwent Neoadjuvant Therapy
Published in Annals of surgical oncology (01-10-2021)“…Purpose Neoadjuvant therapy (NAT) is used to treat not only advanced pancreatic cancer but also resectable lesions. The present study investigated the…”
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Concomitant Intraductal Papillary Mucinous Neoplasm in Pancreatic Ductal Adenocarcinoma Is an Independent Predictive Factor for the Occurrence of New Cancer in the Remnant Pancreas
Published in Annals of surgery (01-05-2020)“…OBJECTIVE:To determine the factors predicting the subsequent development of pancreatic ductal adenocarcinoma in remnant pancreas (PDAC-RP) after partial…”
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