Search Results - "OHTANI, Katsuki"

Complement biomarkers reflect the pathological status of neuromyelitis optica spectrum disorders by Miyamoto, Katsuichi, Minamino, Mai, Kuwahara, Motoi, Tsujimoto, Hiroshi, Ohtani, Katsuki, Wakamiya, Nobutaka, Katayama, Kei-Ichi, Inoue, Norimitsu, Ito, Hidefumi

“…Complement is involved in the pathogenesis of neuroimmune disease, but the detailed pathological roles of the complement pathway remain incompletely…”
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Early Elevation of Complement Factor Ba Is a Predictive Biomarker for Transplant-Associated Thrombotic Microangiopathy by Okamura, Hiroshi, Nakamae, Hirohisa, Shindo, Takero, Ohtani, Katsuki, Hidaka, Yoshihiko, Ohtsuka, Yasufumi, Makuuchi, Yosuke, Kuno, Masatomo, Takakuwa, Teruhito, Harada, Naonori, Nishimoto, Mitsutaka, Nakashima, Yasuhiro, Koh, Hideo, Hirose, Asao, Nakamae, Mika, Wakamiya, Nobutaka, Hino, Masayuki, Inoue, Norimitsu

“…Transplant-associated thrombotic microangiopathy (TA-TMA) is a fatal complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT)…”
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Three pentraxins C-reactive protein, serum amyloid p component and pentraxin 3 mediate complement activation using Collectin CL-P1 by Roy, Nitai, Ohtani, Katsuki, Hidaka, Yoshihiko, Amano, Yoshiro, Matsuda, Yasuyuki, Mori, Kenichiro, Hwang, Insu, Inoue, Norimitsu, Wakamiya, Nobutaka

“…Pentraxins (PTXs) are a superfamily of multifunctional conserved proteins involved in acute-phase responses. Recently, we have shown that collectin placenta 1…”
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Eculizumab for Severe Thrombotic Microangiopathy Secondary to Surgical Invasive Stress and Bleeding by Fujita, Yoko, Terashita, Maho, Yazawa, Masahiko, Yamasaki, Yukitaka, Imamura, Tomonori, Kibayashi, Junichiro, Sawai, Toshihiro, Hidaka, Yoshihiko, Ohtani, Katsuki, Inoue, Norimitsu, Shibagaki, Yugo

“…Atypical hemolytic uremic syndrome (aHUS) is an extremely rare condition caused by an excessive activation of the complement pathway based on genetic or…”
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Changes in Mannose-Binding Lectin and Collectin Kidney 1 Levels in Sepsis Patients With and Without Disseminated Intravascular Coagulation by Hayakawa, Mineji, Ohtani, Katsuki, Wakamiya, Nobutaka

“…In sepsis, systemic coagulation activation frequently causes disseminated intravascular coagulation (DIC), and the uncontrolled activation of the complement…”
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Collectin CL-P1 utilizes C-reactive protein for complement activation by Roy, Nitai, Ohtani, Katsuki, Matsuda, Yasuyuki, Mori, Kenichiro, Hwang, Insu, Suzuki, Yasuhiko, Inoue, Norimitsu, Wakamiya, Nobutaka

“…C-reactive protein (CRP) is a plasma pentraxin family protein that is massively induced as part of the innate immune response to infection and tissue injury…”
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Biological Functions of the Novel Collectins CL-L1, CL-K1, and CL-P1 by Ohtani, Katsuki, Suzuki, Yasuhiko, Wakamiya, Nobutaka

“…Collectins are characterized by a collagen-like sequence and a carbohydrate recognition domain and are members of the vertebrate C-type lectin superfamily…”
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Collectin CL-LK Is a Novel Soluble Pattern Recognition Receptor for Mycobacterium tuberculosis by Troegeler, Anthony, Lugo-Villarino, Geanncarlo, Hansen, Søren, Rasolofo, Voahangy, Henriksen, Maiken Lumby, Mori, Kenichiro, Ohtani, Katsuki, Duval, Carine, Mercier, Ingrid, Bénard, Alan, Nigou, Jérome, Hudrisier, Denis, Wakamiya, Nobutaka, Neyrolles, Olivier

“…Understanding the molecular components of immune recognition of the tuberculosis (TB) bacillus, Mycobacterium tuberculosis, can help designing novel strategies…”
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Collectin Kidney 1 Plays an Important Role in Innate Immunity against Streptococcus pneumoniae Infection by Hwang, Insu, Mori, Kenichiro, Ohtani, Katsuki, Matsuda, Yasuyuki, Roy, Nitai, Kim, YounUck, Suzuki, Yasuhiko, Wakamiya, Nobutaka

“…Collectins are C-type lectins that are involved in innate immunity as pattern recognition molecules. Recently, collectin kidney 1 (CL-K1) has been discovered,…”
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Differential cell-protective function of two resveratrol (trans-3,5,4'-trihydroxystilbene) glucosides against oxidative stress by Hosoda, Ryusuke, Kuno, Atsushi, Hori, Yusuke S, Ohtani, Katsuki, Wakamiya, Nobutaka, Oohiro, Azusa, Hamada, Hiroki, Horio, Yoshiyuki

“…Resveratrol (trans-3,5,4'-trihydroxystilbene; RSV), a natural polyphenol, exerts a beneficial effect on health and diseases. RSV targets and activates the…”
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Scavenger receptor CL-P1 mainly utilizes a collagen-like domain to uptake microbes and modified LDL by Mori, Kenichiro, Ohtani, Katsuki, Jang, SeongJae, Kim, YounUck, Hwang, Insu, Roy, Nitai, Matsuda, Yasuyuki, Suzuki, Yasuhiko, Wakamiya, Nobutaka

“…Collectins are considered to play a role in host defense via complement activation and opsonization, and are composed of a collagen-like domain and a…”
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Comparison of human blood concentrations of collectin kidney 1 and mannan-binding lectin by Yoshizaki, Takayuki, Ohtani, Katsuki, Motomura, Wataru, Jang, Seong-Jae, Mori, Ken-ichiro, Kitamoto, Noritoshi, Yoshida, Itsuro, Suzuki, Yasuhiko, Wakamiya, Nobutaka

“…Mannan-binding lectin (MBL) was first discovered as a collectin in animal blood, and was shown to have such unique characteristics as a collage-like domain and…”
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Scavenger Receptor Collectin Placenta 1 (CL-P1) Predominantly Mediates Zymosan Phagocytosis by Human Vascular Endothelial Cells by Jang, SeongJae, Ohtani, Katsuki, Fukuoh, Atsushi, Yoshizaki, Takayuki, Fukuda, Mitsuko, Motomura, Wataru, Mori, Kenichiro, Fukuzawa, Jun, Kitamoto, Noritoshi, Yoshida, Itsuro, Suzuki, Yasuhiko, Wakamiya, Nobutaka

“…Collectin placenta 1 (CL-P1), a recently discovered scavenger receptor, mediates the uptake of oxidized low density lipoprotein and microbes. In this study, we…”
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Identification and Characterization of a Novel Human Collectin CL-K1 by Keshi, Hiroyuki, Sakamoto, Takashi, Kawai, Takao, Ohtani, Katsuki, Katoh, Tsuyoshi, Jang, Seong-Jae, Motomura, Wataru, Yoshizaki, Takayuki, Fukuda, Mitsuko, Koyama, Satoshi, Fukuzawa, Jun, Fukuoh, Atsushi, Yoshida, Itsuro, Suzuki, Yasuhiko, Wakamiya, Nobutaka

“…Collectins are a family of C‐type lectins with two characteristic structures, collagen like domains and carbohydrate recognition domains. They recognize…”
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New Complement Therapeutics in Complement-Related Diseases by Wakamiya, Nobutaka, Ohtani, Katsuki, Hidaka, Yoshihiko, Inoue, Norimitsu

“…The complement was named after "a complement", a protein molecule that supports an antibody. It was considered previously that the complement mainly…”
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The Membrane-type Collectin CL-P1 Is a Scavenger Receptor on Vascular Endothelial Cells by Ohtani, Katsuki, Suzuki, Yasuhiko, Eda, Souji, Kawai, Takao, Kase, Tetsuo, Keshi, Hiroyuki, Sakai, Yoshinori, Fukuoh, Atsushi, Sakamoto, Takashi, Itabe, Hiroyuki, Suzutani, Tatsuo, Ogasawara, Masahiro, Yoshida, Itsuro, Wakamiya, Nobutaka

“…Collectins are a family of C-type lectins that have collagen-like sequences and carbohydrate recognition domains (CRD). They are involved in host defense…”
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Molecular cloning and functional analysis of scavenger receptor zebrafish CL-P1 by Fukuda, Mitsuko, Ohtani, Katsuki, Jang, Seong-Jae, Yoshizaki, Takayuki, Mori, Ken-ichiro, Motomura, Wataru, Yoshida, Itsuro, Suzuki, Yasuhiko, Kohgo, Yutaka, Wakamiya, Nobutaka

“…Scavenger receptors are generally expressed in macrophages and vascular endothelial cells and some scavenger receptors are thought to contribute to the…”
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Novel collectins play double roles in embryonic and fetal development as well as innate immunity by Ohtani, Katsuki, Wakamiya, Nobutaka

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The induction of human CL-P1 expression in hypoxia/reoxygenation culture condition and rat CL-P1 after ischemic/reperfusion treatment by Koyama, Satoshi, Ohtani, Katsuki, Fukuzawa, Jun, Yao, Naoyuki, Fukuda, Mitsuko, Jang, Seong-Jae, Hasebe, Naoyuki, Kikuchi, Kenjiro, Itabe, Hiroyuki, Yoshida, Itsuro, Suzuki, Yasuhiko, Wakamiya, Nobutaka

“…Oxidative stress-induced endothelial dysfunction and oxidized low-density lipoprotein (LDL) might play a key role in the pathogenesis of atherosclerosis. We…”
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Immunolocalization of a Novel Collectin CL-K1 in Murine Tissues by Motomura, Wataru, Yoshizaki, Takayuki, Ohtani, Katsuki, Okumura, Toshikatsu, Fukuda, Mituko, Fukuzawa, Jun, Mori, Kenichiro, Jang, Seong-Jae, Nomura, Naoki, Yoshida, Itsuro, Suzuki, Yasuhiko, Kohgo, Yutaka, Wakamiya, Nobutaka

“…We have recently identified a novel collectin, CL-K1, that may play a role in innate immunity as a member of the collectin family. In this study using mice, we…”
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