Search Results - "OHTA, Keisuke"
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Understanding subcortical projections to the lateral posterior thalamic nucleus and its subregions using retrograde neural tracing
Published in Frontiers in neuroanatomy (07-08-2024)“…The rat lateral posterior thalamic nucleus (LP) is composed of the rostromedial (LPrm), lateral (LPl), and caudomedial parts, with LPrm and LPl being areas…”
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2
Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation
Published in Nature communications (11-09-2020)“…Endosome maturation depends on membrane contact sites (MCSs) formed between endoplasmic reticulum (ER) and endolysosomes (LyLEs). The mechanism underlying…”
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Human Parainfluenza Virus Type 2 V Protein Modulates Iron Homeostasis
Published in Journal of virology (24-02-2021)“…Intracellular iron concentration is tightly controlled for cell viability. It is known to affect the growth of several viruses, but the molecular mechanisms…”
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4
A Minigenome Study of Hazara Nairovirus Genomic Promoters
Published in Journal of virology (15-03-2019)“…Hazara nairovirus (HAZV) is a trisegmented RNA virus most closely related to Crimean-Congo hemorrhagic fever virus (CCHFV) in the order The terminal roughly 20…”
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A Point Mutation in the Human Parainfluenza Virus Type 2 Nucleoprotein Leads to Two Separate Effects on Virus Replication
Published in Journal of virology (23-02-2022)“…Paramyxovirus genomes, like that of human parainfluenza virus type 2 (hPIV2), have lengths of precisely multiples-of-six nucleotides ("rule of six"), where…”
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Hazara orthonairovirus nucleoprotein facilitates viral cell-to-cell spread by modulating tight junction protein, claudin-1
Published in Frontiers in microbiology (23-05-2023)“…Tight junctions act as a barrier that prevents invasion of pathogens through epithelial cells. This study aims to elucidate the correlation between tight…”
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Hazara Orthonairovirus Nucleoprotein Antagonizes Type I Interferon Production by Inhibition of RIG-I Ubiquitination
Published in Viruses (01-09-2022)“…Viruses have evolved various strategies to evade the host innate immune system. The relationship between nairoviruses and the interferon (IFN) system is poorly…”
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The control of paramyxovirus genome hexamer length and mRNA editing
Published in RNA (Cambridge) (01-04-2018)“…The unusual ability of a human parainfluenza virus type 2 (hPIV2) nucleoprotein point mutation (NP ) to strongly enhance minigenome replication was found to…”
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Profilin2 is required for filamentous actin formation induced by human parainfluenza virus type 2
Published in Virology (New York, N.Y.) (01-07-2019)“…We previously reported that human parainfluenza virus type 2 (hPIV-2) promoted RhoA activation and subsequent filamentous actin (F-actin) formation…”
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The V protein of human parainfluenza virus type 2 promotes RhoA-induced filamentous actin formation
Published in Virology (New York, N.Y.) (01-11-2018)“…We previously demonstrated that human parainfluenza virus type 2 (hPIV-2) induces RhoA activation, which promotes its growth. RhoA controls the equilibrium…”
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Three-dimensional ultrastructural imaging and quantitative analysis of the periodontal ligament
Published in Anatomical science international (01-01-2020)“…The periodontal ligament (PDL) is a unique connective tissue mainly comprising collagen fiber bundles and cells between the roots of teeth and inner walls of…”
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12
Claudin-1 inhibits human parainfluenza virus type 2 dissemination
Published in Virology (New York, N.Y.) (01-05-2019)“…Tight junctions enable epithelial cells to form physical barriers that act as an innate immune defense against respiratory infection. However, the involvement…”
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13
Morphometric analysis in mouse scleral fibroblasts using focused ion beam/scanning electron microscopy
Published in Scientific reports (19-04-2019)“…The sclera as well as the cornea forms the principal part of the outer fibrous coat of the eye, with a primary function of protecting the intraocular contents…”
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Regulation of Hazara virus growth through apoptosis inhibition by viral nucleoprotein
Published in Archives of virology (01-06-2019)“…Hazara virus (HAZV) is closely related to Crimean-Congo hemorrhagic fever virus (CCHFV), but differs in that it is non-pathogenic to humans. Since HAZV was…”
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Common and unique mechanisms of filamentous actin formation by viruses of the genus Orthorubulavirus
Published in Archives of virology (01-04-2020)“…We previously found that infection with human parainfluenza virus type 2 (hPIV-2), a member of the genus Orthorubulavirus, family Paramyxoviridae , causes…”
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A Point Mutation in the RNA-Binding Domain of Human Parainfluenza Virus Type 2 Nucleoprotein Elicits Abnormally Enhanced Polymerase Activity
Published in Journal of virology (01-05-2017)“…The genome RNA of human parainfluenza virus type 2 (hPIV2) that acts as the template for the polymerase complex is entirely encapsidated by the nucleoprotein…”
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Hyaluronic Acid Accelerates Tendon-to-Bone Healing After Rotator Cuff Repair
Published in The American journal of sports medicine (01-12-2017)“…Background: There is growing evidence that the subacromial injection of hyaluronic acid (HA) is effective for pain relief in rotator cuff tears; however, its…”
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18
Correlation of organelle dynamics between light microscopic live imaging and electron microscopic 3D architecture using FIB-SEM
Published in Microscopy (01-04-2021)“…Abstract Correlative light and electron microscopy (CLEM) methods combined with live imaging can be applied to understand the dynamics of organelles. Although…”
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Identification of PDGFRα-positive interstitial cells in the distal segment of the murine vas deferens
Published in Scientific reports (06-04-2021)“…Platelet-derived growth factor receptor-α (PDGFRα)-positive interstitial cells (ICs) are widely distributed in various organs and may be involved in the…”
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Surgical Treatment of a Defect Recurring 22 Years after Closure of an Inferior Sinus Venosus Defect: A Case Report
Published in Journal of Nippon Medical School (25-06-2023)“…Background: Residual shunt after closure of an inferior sinus venosus defect (ISVD) is a rare complication with a high rate of reintervention. Case…”
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