Search Results - "OHNO, NAOHITO"

Fungal Beta-glucans: Structure and Effect on Host Immune Responses by Ohno, Naohito

“…Fungi are eukaryotic microorganisms that show complex life cycles, including both anamorph and teleomorph stages. Beta-1,3-1,6-glucans (BGs) are major cell…”
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The transcription factor ATF7 mediates lipopolysaccharide-induced epigenetic changes in macrophages involved in innate immunological memory by Yoshida, Keisuke, Maekawa, Toshio, Zhu, Yujuan, Renard-Guillet, Claire, Chatton, Bruno, Inoue, Kentaro, Uchiyama, Takeru, Ishibashi, Ken-ichi, Yamada, Takuji, Ohno, Naohito, Shirahige, Katsuhiko, Okada-Hatakeyama, Mariko, Ishii, Shunsuke

“…The role of the stress-induced transcription factor ATF7 in immunity is largely unknown. Ishii and colleagues show that ATF7 represses select innate…”
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Ficolin-1 is a promising therapeutic target for autoimmune diseases by Katayama, Michihito, Ota, Kaori, Nagi-Miura, Noriko, Ohno, Naohito, Yabuta, Norikazu, Nojima, Hiroshi, Kumanogoh, Atsushi, Hirano, Toru

“…An anti-ficolin-1 mAb is effective as therapy for autoimmunity Abstract Previously, we reported that mRNA expression of ficolin-1 (FCN1), a component of the…”
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Dectin-2-induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis by Miyabe, Chie, Miyabe, Yoshishige, Bricio-Moreno, Laura, Lian, Jeffrey, Rahimi, Rod A, Miura, Noriko N, Ohno, Naohito, Iwakura, Yoichiro, Kawakami, Tamihiro, Luster, Andrew D

“…Environmental triggers, including those from pathogens, are thought to play an important role in triggering autoimmune diseases, such as vasculitis, in…”
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Dectin-1 Reactivity to Paramylon Derived from Euglena gracilis EOD-1 by Ishibashi, Ken-ichi, Onaka, Nobuteru, Nishida, Norihisa, Takahashi, Madoka, Adachi, Yoshiyuki, Ohno, Naohito

“…Euglena gracilis is a microalga that has recently attracted attention because of its bioactivities. Paramylon (PM), a major β-1,3-glucan, constitutes 70–80% of…”
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Crucial role of NLRP3 inflammasome in a murine model of Kawasaki disease by Anzai, Fumiya, Watanabe, Sachiko, Kimura, Hiroaki, Kamata, Ryo, Karasawa, Tadayoshi, Komada, Takanori, Nakamura, Jun, Nagi-miura, Noriko, Ohno, Naohito, Takeishi, Yasuchika, Takahashi, Masafumi

“…Kawasaki disease (KD) is a systemic febrile syndrome during childhood that is characterized by coronary arteritis. The etiopathogenesis of KD remains to be…”
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Blocking Dectin-1 prevents colorectal tumorigenesis by suppressing prostaglandin E2 production in myeloid-derived suppressor cells and enhancing IL-22 binding protein expression by Tang, Ce, Sun, Haiyang, Kadoki, Motohiko, Han, Wei, Ye, Xiaoqi, Makusheva, Yulia, Deng, Jianping, Feng, Bingbing, Qiu, Ding, Tan, Ying, Wang, Xinying, Guo, Zehao, Huang, Chanyan, Peng, Sui, Chen, Minhu, Adachi, Yoshiyuki, Ohno, Naohito, Trombetta, Sergio, Iwakura, Yoichiro

“…Dectin-1 (gene Clec7a ), a receptor for β-glucans, plays important roles in the host defense against fungi and immune homeostasis of the intestine. Although…”
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Biological Activity of High-Purity β-1,3-1,6-Glucan Derived from the Black Yeast Aureobasidium pullulans : A Literature Review by Suzuki, Toshio, Kusano, Kisato, Kondo, Nobuhiro, Nishikawa, Kouji, Kuge, Takao, Ohno, Naohito

“…The black yeast produces abundant soluble β-1,3-1,6-glucan-a functional food ingredient with known health benefits. For use as a food material, soluble…”
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Coronary Vasculitis Induced in Mice by the Cell Wall Mannoprotein of Candida krusei by Yanai, Chiho, Tanaka, Hiroaki, Miura, Noriko N., Ishibashi, Ken-ichi, Yamanaka, Daisuke, Ohnishi, Hiroaki, Ohno, Naohito, Adachi, Yoshiyuki

“…Kawasaki disease (KD) is an inflammatory disease that was identified by Professor Tomisaku Kawasaki in 1961. Candida albicans-derived substances, such as the…”
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Latent 1,3-β-D-glucan acts as an adjuvant for allergen-specific IgE production induced by Japanese cedar pollen exposure by Kanno, Takashi, Adachi, Yoshiyuki, Ohashi-Doi, Katsuyo, Matsuhara, Hiroki, Hiratsuka, Rie, Ishibashi, Ken-ichi, Yamanaka, Daisuke, Ohno, Naohito

“…The pollen grains of several plant species contain 1,3-β-D-glucan (BG). BG activates dendritic cells (DCs) and subsequently regulates the innate immune…”
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Enzymatically polymerised polyphenols prepared from various precursors potentiate antigen-specific immune responses in both mucosal and systemic compartments in mice by Tada, Rui, Ogasawara, Miki, Yamanaka, Daisuke, Sakurai, Yasuhiro, Negishi, Yoichi, Kiyono, Hiroshi, Ohno, Naohito, Kunisawa, Jun, Aramaki, Yukihiko

“…Despite significant modern medicine progress, having an infectious disease is a major risk factor for humans. Mucosal vaccination is now widely considered as…”
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Nociceptors Boost the Resolution of Fungal Osteoinflammation via the TRP Channel-CGRP-Jdp2 Axis by Maruyama, Kenta, Takayama, Yasunori, Kondo, Takeshi, Ishibashi, Ken-ichi, Sahoo, Bikash Ranjan, Kanemaru, Hisashi, Kumagai, Yutaro, Martino, Mikaël M., Tanaka, Hiroki, Ohno, Naohito, Iwakura, Yoichiro, Takemura, Naoki, Tominaga, Makoto, Akira, Shizuo

“…Candida albicans can enter skeletal tissue through a skin wound in an immunocompromised host or by contamination during orthopedic surgery. Such Candida…”
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The Core Fucose on an IgG Antibody is an Endogenous Ligand of Dectin‐1 by Manabe, Yoshiyuki, Marchetti, Roberta, Takakura, Yohei, Nagasaki, Masahiro, Nihei, Wataru, Takebe, Tomoyuki, Tanaka, Katsunori, Kabayama, Kazuya, Chiodo, Fabrizio, Hanashima, Shinya, Kamada, Yoshihiro, Miyoshi, Eiji, Dulal, Hari Prasad, Yamaguchi, Yoshiki, Adachi, Yoshiyuki, Ohno, Naohito, Tanaka, Hiroshi, Silipo, Alba, Fukase, Koichi, Molinaro, Antonio

“…The core fucose, a major modification of N‐glycans, is implicated in immune regulation, such as the attenuation of the antibody‐dependent cell‐mediated…”
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High-parameter immune profiling and subjective health assessment of the immunomodulatory effects of paramylon-rich Euglena gracilis EOD-1: A randomized, double-blind, placebo-controlled, parallel-group study by Kawano, Takanori, Miura, Atsushi, Naito, Junko, Nishida, Norihisa, Ishibashi, Ken-ichi, Adachi, Yoshiyuki, Ohno, Naohito, Naito, Yuji

“…[Display omitted] •We investigated the effects of paramylon-rich Euglena gracilis EOD-1 (PM EOD-1).•Physical condition and immune function were studied in a…”
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N-Terminal (1→3)-β-d-Glucan Recognition Proteins from Insects Recognize the Difference in Ultra-Structures of (1→3)-β-d-Glucan by Adachi, Yoshiyuki, Ishii, Masaki, Kanno, Takashi, Tetsui, Junko, Ishibashi, Ken-Ichi, Yamanaka, Daisuke, Miura, Noriko, Ohno, Naohito

“…Recognition of (1→3)-β-d-glucans (BGs) by invertebrate β-1,3-d-glucan recognition protein (BGRP) plays a significant role in the activation of Toll pathway and…”
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Interleukin-1beta Inhibition Attenuates Vasculitis in a Mouse Model of Kawasaki Disease by Hashimoto, Yoshiaki, Fukazawa, Ryuji, Nagi-Miura, Noriko, Ohno, Naohito, Suzuki, Nobuko, Katsube, Yasuhiro, Kamisago, Mitsuhiro, Akao, Miharu, Watanabe, Makoto, Hashimoto, Koji, Tsuno, Kanae, Matsui, Ryosuke, Itoh, Yasuhiko

“…Background: Kawasaki disease (KD), a systemic vasculitis, is suspected to be related to abnormalities in innate immunity. Based on the important role of IL-1…”
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Adipose tissue‐derived stem cells suppress coronary arteritis of Kawasaki disease in vivo by Uchimura, Ryoichi, Ueda, Takahiro, Fukazawa, Ryuji, Hayakawa, Jun, Ohashi, Ryuji, Nagi‐Miura, Noriko, Ohno, Naohito, Migita, Makoto, Itoh, Yasuhiko

“…Background Kawasaki disease (KD) is a systemic inflammatory disease resulting in an acute febrile syndrome commonly affecting children younger than 5 years…”
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Development of a Highly Sensitive β-Glucan Detection System Using Scanning Single-Molecule Counting Method by Adachi, Yoshiyuki, Nakata, Hidetaka, Tanabe, Tetsuya, Yamanaka, Daisuke, Kanno, Takashi, Ishibashi, Ken-ichi, Ohno, Naohito

“…To overcome the limitations of the Limulus amebocyte lysate (LAL) assay method for the diagnosis of invasive fungal infection, we applied a reaction system…”
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The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors by Takai, Toshiyuki, Saijo, Shinobu, Shibuya, Akira, Morris, Stephan W, Inui, Masanori, Ohno, Naohito, Yoshida, Hiroki, Penninger, Josef M, Hara, Hiromitsu, Saito, Takashi, Xue, Liquan, Takeuchi, Arata, Imanishi, Takayuki, Iwakura, Yoichiro, Koseki, Haruhiko, Ishihara, Chitose

“…Immunoreceptor tyrosine-based activation motifs (ITAMs) are crucial in antigen receptor signaling in acquired immunity. Although receptors associated with the…”
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Characterization of a thermostable mutant of Agaricus brasiliensis laccase created by phylogeny-based design by Hamuro, Yuhi, Tajima, Katsuya, Matsumoto-Akanuma, Akiko, Sakamoto, Sayaka, Furukawa, Ryutaro, Yamagishi, Akihiko, Ohno, Naohito, Akanuma, Satoshi

“…Laccases are enzymes that oxidize various aromatic compounds, and therefore they have attracted much attention from the standpoints of medical and industrial…”
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