Search Results - "OHNO, Ayako"

Morin attenuates dexamethasone-mediated oxidative stress and atrophy in mouse C2C12 skeletal myotubes by Ulla, Anayt, Uchida, Takayuki, Miki, Yukari, Sugiura, Kosuke, Higashitani, Atsushi, Kobayashi, Takeshi, Ohno, Ayako, Nakao, Reiko, Hirasaka, Katsuya, Sakakibara, Iori, Nikawa, Takeshi

“…Glucocorticoids are the drugs most commonly used to manage inflammatory diseases. However, they are prone to inducing muscle atrophy by increasing muscle…”
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VEGF pathway-targeting drugs induce evasive adaptation by activation of neuropilin-1/cMet in colon cancer cells by Tomida, Chisato, Yamagishi, Naoko, Nagano, Hikaru, Uchida, Takayuki, Ohno, Ayako, Hirasaka, Katsuya, Nikawa, Takeshi, Teshima-Kondo, Shigetada

“…Anti-angiogenic therapies targeting vascular endothelial growth factor (VEGF) and its receptor (VEGF-R) are important treatments for a number of human…”
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Ubiquitin Ligase Cbl-b Is a Negative Regulator for Insulin-Like Growth Factor 1 Signaling during Muscle Atrophy Caused by Unloading by Nakao, Reiko, Hirasaka, Katsuya, Goto, Jumpei, Ishidoh, Kazumi, Yamada, Chiharu, Ohno, Ayako, Okumura, Yuushi, Nonaka, Ikuya, Yasutomo, Koji, Baldwin, Kenneth M., Kominami, Eiki, Higashibata, Akira, Nagano, Keisuke, Tanaka, Keiji, Yasui, Natsuo, Mills, Edward M., Takeda, Shin'ichi, Nikawa, Takeshi

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Reactive oxygen species upregulate expression of muscle atrophy-associated ubiquitin ligase Cbl-b in rat L6 skeletal muscle cells by Uchida, Takayuki, Sakashita, Yoshihiro, Kitahata, Kanako, Yamashita, Yui, Tomida, Chisato, Kimori, Yuki, Komatsu, Akio, Hirasaka, Katsuya, Ohno, Ayako, Nakao, Reiko, Higashitani, Atsushi, Higashibata, Akira, Ishioka, Noriaki, Shimazu, Toru, Kobayashi, Takeshi, Okumura, Yuushi, Choi, Inho, Oarada, Motoko, Mills, Edward M, Teshima-Kondo, Shigetada, Takeda, Shin'ichi, Tanaka, Eiji, Tanaka, Keiji, Sokabe, Masahiro, Nikawa, Takeshi

“…Unloading-mediated muscle atrophy is associated with increased reactive oxygen species (ROS) production. We previously demonstrated that elevated ubiquitin…”
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Structure of PAS-Linked Histidine Kinase and the Response Regulator Complex by Yamada, Seiji, Sugimoto, Hiroshi, Kobayashi, Miki, Ohno, Ayako, Nakamura, Hiro, Shiro, Yoshitsugu

“…We determined the structure of the complex of the sensory histidine kinase (HK) and its cognate response regulator (RR) in the two-component signal…”
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Flavones Inhibit LPS-Induced Atrogin-1/MAFbx Expression in Mouse C2C12 Skeletal Myotubes by SHIOTA, Chieko, ABE, Tomoki, KAWAI, Nobuhiko, OHNO, Ayako, TESHIMA-KONDO, Shigetada, MORI, Hiroyo, TERAO, Junji, TANAKA, Eiji, NIKAWA, Takeshi

“…Muscle atrophy is a complex process that occurs as a consequence of various stress events. Muscle atrophy-associated genes (atrogenes) such as atrogin-1/MAFbx…”
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Oral intake of rice overexpressing ubiquitin ligase inhibitory pentapeptide prevents atrophy in denervated skeletal muscle by Nakao, Reiko, Shen, Weilin, Shimajiri, Yasuka, Kainou, Kumiko, Sato, Yuki, Ulla, Anayt, Ohnishi, Kohta, Ninomiya, Miyuki, Ohno, Ayako, Uchida, Takayuki, Tanaka, Mitsuru, Akama, Kazuhito, Matsui, Toshiro, Nikawa, Takeshi

“…We previously reported that intramuscular injections of ubiquitin ligase CBLB inhibitory pentapeptide (Cblin; Asp-Gly-pTyr-Met-Pro) restored lost muscle mass…”
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Ubiquitin ligase Cbl-b and obesity-induced insulin resistance [Review] by Abe, Tomoki, Hirasaka, Katsuya, Kohno, Shohei, Ochi, Arisa, Yamagishi, Naoko, Ohno, Ayako, Teshima-Kondo, Shigetada, Nikawa, Takeshi

“…Obesity causes type 2 diabetes, atherosclerosis and cardiovascular diseases by inducing systemic insulin resistance. It is now recognized that obesity is…”
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Regorafenib induces adaptive resistance of colorectal cancer cells via inhibition of vascular endothelial growth factor receptor by Tomida, Chisato, Nagano, Hikaru, Yamagishi, Naoko, Uchida, Takayuki, Ohno, Ayako, Hirasaka, Katsuya, Nikawa, Takeshi, Teshima-Kondo, Shigetada

“…Recently, inhibition of tumor angiogenesis has become an important anti-cancer therapy. Tumor angiogenesis is regulated by multiple signaling pathways,…”
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N-myristoylated ubiquitin ligase Cbl-b inhibitor prevents on glucocorticoid-induced atrophy in mouse skeletal muscle by Ochi, Arisa, Abe, Tomoki, Nakao, Reiko, Yamamoto, Yoriko, Kitahata, Kanako, Takagi, Marina, Hirasaka, Katsuya, Ohno, Ayako, Teshima-Kondo, Shigetada, Taesik, Gwag, Choi, Inho, Kawamura, Tomoyuki, Nemoto, Hisao, Mukai, Rie, Terao, Junji, Nikawa, Takeshi

“…•The penta-peptide DGpYMP (Cblin) inhibited the muscle atrophy caused by glucocorticoids.•N-myristoylated Cblin prevented such muscle atrophy in vitro and in…”
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Synthesis of boradiazaindacene–imidazopyrazinone conjugate as lipophilic and yellow-chemiluminescent chemosensor for superoxide radical anion by Saito, Ryota, Ohno, Ayako, Ito, Eri

“…As a chemiluminescent chemosensor that emits yellow light on reacting with a superoxide radical anion (O2−) and has a lipophilic character, a…”
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Isoflavones Derived from Soy Beans Prevent MuRF1-Mediated Muscle Atrophy in C2C12 Myotubes through SIRT1 Activation by HIRASAKA, Katsuya, MAEDA, Tasuku, IKEDA, Chika, HARUNA, Marie, KOHNO, Shohei, ABE, Tomoki, OCHI, Arisa, MUKAI, Rie, OARADA, Motoko, ESHIMA-KONDO, Shigetada, OHNO, Ayako, OKUMURA, Yuushi, TERAO, Junji, NIKAWA, Takeshi

“…Proinflammatory cytokines are factors that induce ubiquitin-proteasome-dependent proteolysis in skeletal muscle, causing muscle atrophy. Although isoflavones,…”
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Antiangiogenic agent sunitinib induces epithelial to mesenchymal transition and accelerates motility of colorectal cancer cells by Tomida, Chisato, Yamagishi, Naoko, Nagano, Hikaru, Uchida, Takayuki, Ohno, Ayako, Hirasaka, Katsuya, Nikawa, Takeshi, Teshima-Kondo, Shigetada

“…Although vascular endothelial growth factor receptor (VEGF-R)-targeted antiangiogenic agents are important treatment for a number of human malignancies, there…”
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Prevention of skeletal muscle atrophy in vitro using anti-ubiquitination oligopeptide carried by atelocollagen by Kawai, Nobuhiko, Hirasaka, Katsuya, Maeda, Tasuku, Haruna, Marie, Shiota, Chieko, Ochi, Arisa, Abe, Tomoki, Kohno, Shohei, Ohno, Ayako, Teshima-Kondo, Sigetada, Mori, Hiroyo, Tanaka, Eiji, Nikawa, Takeshi

“…Skeletal muscle atrophy occurs when the rate of protein degradation exceeds that of protein synthesis in various catabolic conditions, such as fasting, disuse,…”
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Capric Acid Up-Regulates UCP3 Expression without PDK4 Induction in Mouse C2C12 Myotubes by ABE, Tomoki, HIRASAKA, Katsuya, KOHNO, Shohei, TOMIDA, Chisato, HARUNA, Marie, UCHIDA, Takayuki, OHNO, Ayako, OARADA, Motoko, TESHIMA-KONDO, Shigetada, OKUMURA, Yuushi, CHOI, Inho, AOYAMA, Toshiaki, TERAO, Junji, NIKAWA, Takeshi

“…Uncoupling protein 3 (UCP3) and pyruvate dehydrogenase kinase 4 (PDK4) in skeletal muscle are key regulators of the glucose and lipid metabolic processes that…”
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UCP3 is associated with Hax-1 in mitochondria in the presence of calcium ion by Hirasaka, Katsuya, Mills, Edward M., Haruna, Marie, Bando, Aki, Ikeda, Chika, Abe, Tomoki, Kohno, Shohei, Nowinski, Sara M., Lago, Cory U., Akagi, Ken-ichi, Tochio, Hidehito, Ohno, Ayako, Teshima-Kondo, Shigetada, Okumura, Yuushi, Nikawa, Takeshi

“…Uncoupling protein 3 (UCP3) is known to regulate energy dissipation, proton leakage, fatty acid oxidation, and oxidative stress. To identify the putative…”
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Unloading stress disturbs muscle regeneration through perturbed recruitment and function of macrophages by Kohno, Shohei, Yamashita, Yui, Abe, Tomoki, Hirasaka, Katsuya, Oarada, Motoko, Ohno, Ayako, Teshima-Kondo, Shigetada, Higashibata, Akira, Choi, Inho, Mills, Edward M, Okumura, Yuushi, Terao, Junji, Nikawa, Takeshi

“…Skeletal muscle is one of the most sensitive tissues to mechanical loading, and unloading inhibits the regeneration potential of skeletal muscle after injury…”
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The malignant progression effects of regorafenib in human colon cancer cells by Tomida, Chisato, Aibara, Kana, Yamagishi, Naoko, Yano, Chiaki, Nagano, Hikaru, Abe, Tomoki, Ohno, Ayako, Hirasaka, Katsuya, Nikawa, Takeshi, Teshima-Kondo, Shigetada

“…A number of anti-angiogenic drugs targeting vascular endothelial growth factor receptors (VEGF-R) have developed and enabled significant advances in cancer…”
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Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza by Ohno, Ayako, Maita, Nobuo, Tabata, Takanori, Nagano, Hikaru, Arita, Kyohei, Ariyoshi, Mariko, Uchida, Takayuki, Nakao, Reiko, Ulla, Anayt, Sugiura, Kosuke, Kishimoto, Koji, Teshima-Kondo, Shigetada, Okumura, Yuushi, Nikawa, Takeshi

“…Infection of certain influenza viruses is triggered when its HA is cleaved by host cell proteases such as proprotein convertases and type II transmembrane…”
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Effects of dietary soy protein on skeletal muscle volume and strength in humans with various physical activities by Hashimoto, Rie, Sakai, Atsuko, Murayama, Masumi, Ochi, Arisa, Abe, Tomoki, Hirasaka, Katsuya, Ohno, Ayako, Teshima-Kondo, Shigetada, Yanagawa, Hiroaki, Yasui, Natsuo, Inatsugi, Mikiko, Doi, Daisuke, Takeda, Masanori, Mukai, Rie, Terao, Junji, Nikawa, Takeshi

“…Background: In recent years, the number of bedridden people is rapidly increasing due to aging or lack of exercise in Japan. This problem is becoming more…”
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