Search Results - "OHNISHI, Kazunori"

Clinical outcomes of second‐generation tyrosine kinase inhibitors versus imatinib in older patients with CML by Ono, Takaaki, Takahashi, Naoto, Kizaki, Masahiro, Kawaguchi, Tatsuya, Suzuki, Ritsuro, Yamamoto, Kazuhito, Ohnishi, Kazunori, Naoe, Tomoki, Matsumura, Itaru

“…Age and comorbidities are important factors to be considered in the selection of tyrosine kinase inhibitors (TKIs) for first‐line treatment in patients with…”
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Prognostic effect of comorbidities in patients with chronic myeloid leukemia treated with a tyrosine kinase inhibitor by Ono, Takaaki, Takahashi, Naoto, Kizaki, Masahiro, Kawaguchi, Tatsuya, Suzuki, Ritsuro, Yamamoto, Kazuhito, Ohnishi, Kazunori, Naoe, Tomoki, Matsumura, Itaru

“…Comorbidities at diagnosis among patients with chronic myeloid leukemia in chronic phase (CML‐CP) may affect their overall survival (OS) rate even in the…”
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Impact of CYP3A5 and ABCB1 Gene Polymorphisms on Fentanyl Pharmacokinetics and Clinical Responses in Cancer Patients Undergoing Conversion to a Transdermal System by Takashina, Yoshiaki, Naito, Takafumi, Mino, Yasuaki, Yagi, Tatsuya, Ohnishi, Kazunori, Kawakami, Junichi

“…The aim of this study was to evaluate the influence of CYP3A5 and ABCB1 gene polymorphisms on fentanyl pharmacokinetics and clinical responses in cancer…”
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Angiosarcoma arising in a traumatic scar by Hattori, Mai, Ohnishi, Kazunori

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Case of generalized pustular psoriasis presenting with both pleural effusion and pericardial effusion collection by Kuriyama, Yuko, Ohnishi, Kazunori

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PML-RARα inhibitors (ATRA, tamibaroten, arsenic troxide) for acute promyelocytic leukemia by Ohnishi, Kazunori

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A randomized comparison of 4 courses of standard-dose multiagent chemotherapy versus 3 courses of high-dose cytarabine alone in postremission therapy for acute myeloid leukemia in adults: the JALSG AML201 Study by Miyawaki, Shuichi, Ohtake, Shigeki, Fujisawa, Shin, Kiyoi, Hitoshi, Shinagawa, Katsuji, Usui, Noriko, Sakura, Toru, Miyamura, Koichi, Nakaseko, Chiaki, Miyazaki, Yasushi, Fujieda, Atsushi, Nagai, Tadashi, Yamane, Takahisa, Taniwaki, Masafumi, Takahashi, Masatomo, Yagasaki, Fumiharu, Kimura, Yukihiko, Asou, Norio, Sakamaki, Hisashi, Handa, Hiroshi, Honda, Sumihisa, Ohnishi, Kazunori, Naoe, Tomoki, Ohno, Ryuzo

“…We conducted a prospective randomized study to assess the optimal postremission therapy for adult acute myeloid leukemia in patients younger than 65 years in…”
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A multicenter, phase II study of full-dose THP-COP therapy for elderly patients with newly diagnosed, advanced-stage, aggressive non-Hodgkin lymphoma by Ohmachi, Ken, Ogura, Michinori, Kagami, Yoshitoyo, Imai, Yosuke, Hirose, Takayuki, Kinoshita, Tomohiro, Nagai, Hirokazu, Ohnishi, Kazunori, Hotta, Tomomitsu

“…The cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) regimen, containing doxorubicin (DXR), which is a key drug for aggressive non-Hodgkin…”
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Detection of human papillomavirus in actinic keratosis by Kuriyama, Yuko, Shimizu, Akira, Ohnishi, Kazunori, Ishikawa, Osamu

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Trough plasma concentration of imatinib reflects BCR–ABL kinase inhibitory activity and clinical response in chronic‐phase chronic myeloid leukemia: A report from the BINGO study by Ishikawa, Yuichi, Kiyoi, Hitoshi, Watanabe, Keisuke, Miyamura, Koichi, Nakano, Yasuyuki, Kitamura, Kunio, Kohno, Akio, Sugiura, Isamu, Yokozawa, Toshiya, Hanamura, Akitoshi, Yamamoto, Kazuhito, Iida, Hiroatsu, Emi, Nobuhiko, Suzuki, Ritsuro, Ohnishi, Kazunori, Naoe, Tomoki

“…Pharmacokinetic (PK) factors have been suggested to be involved in the unfavorable clinical responses of chronic myeloid leukemia (CML) patients treated with…”
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Treatment outcomes of chronic-phase chronic myeloid leukemia with resistance and/or intolerance to a 1st-line tyrosine kinase inhibitor in Japan: the results of the New TARGET study 2nd-line by Sakurai, Masatoshi, Okamoto, Shinichiro, Matsumura, Itaru, Murakami, Satsuki, Takizawa, Makiko, Waki, Masato, Hirano, Daiki, Watanabe-Nakaseko, Reiko, Kobayashi, Naoki, Iino, Masaki, Mitsui, Hideki, Ishikawa, Yuichi, Takahashi, Naoto, Kawaguchi, Tatsuya, Suzuki, Ritsuro, Yamamoto, Kazuhito, Kizaki, Masahiro, Ohnishi, Kazunori, Naoe, Tomoki, Akashi, Koichi

“…We herein report the results of the New TARGET study 2nd-line, which collected data on patients with chronic-phase (CP) chronic myeloid leukemia (CML) who…”
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Phase II study of FLAGM (fludarabine + high-dose cytarabine + granulocyte colony-stimulating factor + mitoxantrone) for relapsed or refractory acute myeloid leukemia by Hatsumi, Nahoko, Miyawaki, Shuichi, Yamauchi, Takahiro, Takeshita, Akihiro, Komatsu, Norio, Usui, Noriko, Arai, Yukihiro, Ishida, Fumihiro, Morii, Takeshi, Kano, Yasuhiko, Ogura, Michinori, Machida, Shinichiro, Nishii, Kazuhiro, Honda, Sumihisa, Ohnishi, Kazunori, Naoe, Tomoki

“…Given the poor prognosis of patients with relapsed/refractory acute myeloid leukemia (AML), better therapy is needed. Fludarabine enhances the efficacy of…”
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Nilotinib Vs. Dasatinib in Achieving MR4.5 for Newly Diagnosed Chronic Myeloid Leukemia: Results of the Prospective Randomized Phase 3 Study, JALSG CML212 by Matsumura, Itaru, Ohtake, Shigeki, Atsuta, Yoshiko, Kurata, Mio, Minami, Yosuke, Takahashi, Naoto, Nakaseko, Chiaki, Iriyama, Noriyoshi, Fujimaki, Katsumichi, Kakihana, Kazuhiko, Ogasawara, Yoji, ONO, Takaaki, Okada, Masaya, Tauchi, Tetsuzo, Miyamoto, Toshihiro, Ohnishi, Kazunori, Sakaida, Emiko, Fujisawa, Shin, Kobayashi, Yukio, Asou, Norio, Kiyoi, Hitoshi, Miyazaki, Yasushi, Naoe, Tomoki

“…▪ Background: Treatment-free remission (TFR) is a new therapeutic goal for chronic myeloid leukemia in chronic phase (CML-CP). Deep molecular response (DMR) is…”
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Tamibarotene as maintenance therapy for acute promyelocytic leukemia: results from a randomized controlled trial by Shinagawa, Katsuji, Yanada, Masamitsu, Sakura, Toru, Ueda, Yasunori, Sawa, Masashi, Miyatake, Junichi, Dobashi, Nobuaki, Kojima, Minoru, Hatta, Yoshihiro, Emi, Nobuhiko, Tamaki, Shigehisa, Gomyo, Hiroshi, Yamazaki, Etsuko, Fujimaki, Katsumichi, Asou, Norio, Matsuo, Keitaro, Ohtake, Shigeki, Miyazaki, Yasushi, Ohnishi, Kazunori, Kobayashi, Yukio, Naoe, Tomoki

“…The introduction of all-trans-retinoic acid (ATRA) has significantly improved outcomes for acute promyelocytic leukemia (APL), although a subset of patients…”
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Decreased level of phosphatidylcholine (16:0/20:4) in multiple myeloma cells compared to plasma cells: a single-cell MALDI–IMS approach by Hossen, Md Amir, Nagata, Yasuyuki, Waki, Michihiko, Ide, Yoshimi, Takei, Shiro, Fukano, Hana, Romero-Perez, Gustavo A, Tajima, Shogo, Yao, Ikuko, Ohnishi, Kazunori, Setou, Mitsutoshi

“…Lipid metabolic changes under diseased conditions, particularly in solid tumors, are attracting increased attention. However, in non-solid tumors, including…”
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Phase I and II study of azacitidine in Japanese patients with myelodysplastic syndromes by Uchida, Toshiki, Ogawa, Yoshiaki, Kobayashi, Yukio, Ishikawa, Takayuki, Ohashi, Haruhiko, Hata, Tomoko, Usui, Noriko, Taniwaki, Masafumi, Ohnishi, Kazunori, Akiyama, Hideki, Ozawa, Keiya, Ohyashiki, Kazuma, Okamoto, Shinichiro, Tomita, Akihiro, Nakao, Shinji, Tobinai, Kensei, Ogura, Michinori, Ando, Kiyoshi, Hotta, Tomomitsu

“…Azacitidine, an inhibitor of DNA methyltransferase, is reported to have antileukemic efficacy and is approved for the treatment of myelodysplastic syndromes in…”
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R‐High‐CHOP/CHASER/LEED with autologous stem cell transplantation in newly diagnosed mantle cell lymphoma: JCOG0406 STUDY by Ogura, Michinori, Yamamoto, Kazuhito, Morishima, Yasuo, Wakabayashi, Masashi, Tobinai, Kensei, Ando, Kiyoshi, Uike, Naokuni, Kurosawa, Mitsutoshi, Gomyo, Hiroshi, Taniwaki, Masafumi, Nosaka, Kisato, Tsukamoto, Norifumi, Shimoyama, Tatsu, Fukuhara, Noriko, Yakushijin, Yoshihiro, Ohnishi, Kazunori, Miyazaki, Kana, Sawada, Kenichi, Takayama, Nobuyuki, Hanamura, Ichiro, Nagai, Hirokazu, Kobayashi, Hirofumi, Usuki, Kensuke, Kobayashi, Naoki, Ohyashiki, Kazuma, Utsumi, Takahiko, Kumagai, Kyoya, Maruyama, Dai, Ohmachi, Ken, Matsuno, Yoshihiro, Nakamura, Shigeo, Hotta, Tomomitsu, Tsukasaki, Kunihiro

“…Although induction immunochemotherapy including high‐dose cytarabine and rituximab followed by high‐dose chemotherapy (HDC) with autologous stem cell…”
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Phase II study of imatinib‐based chemotherapy for newly diagnosed BCR‐ABL‐positive acute lymphoblastic leukemia by Fujisawa, Shin, Mizuta, Shuichi, Akiyama, Hideki, Ueda, Yasunori, Aoyama, Yasutaka, Hatta, Yoshihiro, Kakihana, Kazuhiko, Dobashi, Nobuaki, Sugiura, Isamu, Onishi, Yasushi, Maeda, Tomoya, Imai, Kiyotoshi, Ohtake, Shigeki, Miyazaki, Yasushi, Ohnishi, Kazunori, Matsuo, Keitaro, Naoe, Tomoki

“…This study investigated the efficacy of imatinib based therapy with intensified consolidation therapy in patients with Philadelphia chromosome (Ph)‐positive…”
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Impact of genetic and non-genetic factors on clinical responses to prochlorperazine in oxycodone-treated cancer patients by Tashiro, Masaki, Naito, Takafumi, Ohnishi, Kazunori, Kagawa, Yoshiyuki, Kawakami, Junichi

“…The contributions of DRD2 and OPRM1 genetic variants to clinical responses to prochlorperazine remain to be clarified in opioid-treated patients. We evaluated…”
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A multicenter, phase II study of R-THP-COP therapy for elderly patients with newly diagnosed, advanced-stage, indolent B-cell lymphoma by Ohnishi, Kazunori, Ohmachi, Ken, Ando, Kiyoshi, Yamamoto, Kazuhito, Ito, Tatsuya, Tanimoto, Mitsune, Ohbayashi, Kaneyuki, Ohyashiki, Kazuma, Tsukasaki, Kunihiro, Naito, Kensuke, Suzuki, Takayo, Ono, Takaaki, Miyamura, Koichi, Kagami, Yoshitoyo, Kinoshita, Tomohiro, Hotta, Tomomitsu, Ogura, Michinori

“…The optimal combined chemotherapy regimen with rituximab has yet to be established for elderly patients with advanced-stage indolent B-cell lymphoma (B-NHL). A…”
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