Search Results - "OHKOSHI, SHOWGO"

Risk factors and the effect of interferon therapy in the development of hepatocellular carcinoma: A multivariate analysis in 343 patients by KUWANA, KENJI, ICHIDA, TAKAFUMI, KAMIMURA, TOMOTERU, OHKOSHI, SHOWGO, OGATA, NORIO, HARADA, TAKESHI, ENDOH, KAZUO, ASAKURA, HITOSHI

“…ABSTRACT The aims of the present study were to clarify the risk factors for the development of hepatocellular carcinoma (HCC) in chronic hepatitis C virus…”
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Molecular structure of the Japanese hepatitis C viral genome by Kato, Nobuyuki, Hijikata, Makoto, Nakagawa, Mosanori, Ootsuyama, Yuko, Muraiso, Kanae, Ohkoshi, Showgo, Shimotohno, Kunitada

“…The amino acid sequence of the polyprotein deduced from the nucleotide sequence of the Japanese hepatitis C virus genome (N. Kato et. al. (1990) Proc. Natl…”
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Japanese Isolates of the Non-A, Non-B Hepatitis Viral Genome Show Sequence Variations from the Original Isolate in the U.S.A by KATO, Nobuyuki, OHKOSHI, Showgo, SHIMOTOHNO, Kunitada

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Molecular Cloning of the Human Hepatitis C Virus Genome From Japanese Patients with Non-A, Non-B Hepatitis by Kato, Nobuyuki, Hijikata, Makoto, Ootsuyama, Yuko, Nakagawa, Masanori, Ohkoshi, Showgo, Sugimura, Takashi, Shimotohno, Kunitada

“…The nucleotide sequence of the Japanese type of hepatitis C virus (HCV-J) genome, consisting of 9413 nucleotides, was determined by analyses of cDNA clones…”
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Humoral immune response to hypervariable region 1 of the putative envelope glycoprotein (gp70) of hepatitis C virus by KATO, N, SEKIYA, H, OOTSUYAMA, Y, NAKAZAWA, T, HIJIKATA, M, OHKOSHI, S, SHIMOTOHNO, K

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Genetic drift in hypervariable region 1 of the viral genome in persistent hepatitis C virus infection by Kato, N, Ootsuyama, Y, Sekiya, H, Ohkoshi, S, Nakazawa, T, Hijikata, M, Shimotohno, K

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Characterization of hypervariable regions in the putative envelope protein of hepatitis C virus by Kato, N, Ootsuyama, Y, Ohkoshi, S, Nakazawa, T, Sekiya, H, Hijikata, M, Shimotohno, K

“…We previously identified two hypervariable regions [HVR1 (27 amino acids) and HVR2 (7 amino acids)] in the putative envelope glycoprotein (gp70) by comparison…”
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Marked sequence diversity in the putative envelope proteins of hepatitis C viruses by Kato, N, Ootsuyama, Y, Tanaka, T, Nakagawa, M, Nakazawa, T, Muraiso, K, Ohkoshi, S, Hijikata, M, Shimotohno, K

“…The nucleotide sequences of cDNAs (414 base pairs) encoding parts of putative envelope proteins (gp35 and gp70) of 40 isolates of hepatitis C virus (HCV-J)…”
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Characterization of the 5' noncoding and structural region of the hepatitis C virus genome from patients with non-A, non-B hepatitis responding differently to interferon treatment by Nakazawa, T, Kato, N, Ohkoshi, S, Shibuya, A, Shimotohno, K

“…We examined 14 patients with hepatitis C caused by infection with the hepatitis C virus-II genotype to understand differences in responsiveness to interferon…”
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Distribution of plural HCV types in Japan by Kato, N, Ootsuyama, Y, Ohkoshi, S, Nakazawa, T, Mori, S, Hijikata, M, Shimotohno, K

“…A detection system was developed to distinguish the four different HCV genomes [HCV-J, HCV-US, HCV-K2 and group II HCV (HCV-GII)], involving reverse…”
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Detection of HBV DNA in non-A, non-B hepatic tissues using the polymerase chain reaction assay by Ohkoshi, S

“…The polymerase chain reaction (PCR) followed by Southern blotting was used to examine the presence of hepatitis B virus (HBV) DNA in non-cancerous liver tissue…”
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Prevalence of Antibody against Non‐A, non‐B Hepatitis Virus in Japanese Patients with Hepatocellular Carcinoma by Ohkoshi, Showgo, Kojima, Hideo, Tawaraya, Hironobu, Miyajima, Tohru, Kamimura, Tomoteru, Asakura, Hitoshi, Satoh, Akira, Hirose, Shinichi, Hijikata, Makoto, Kato, Nobuyuki, Shimotohno, Kunitada

“…Antibodies against a possible causative agent of non‐A, non‐B hepatitis, hepatitis C virus (HCV), in Japanese patients with hepatocellular carcinoma were…”
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A retrospective study of hepatitis C virus carriers in a local endemic town in Japan : a possible presence of asymptomatic carrier by OHKOSHI, S, TAWARAYA, H, KUWANA, K, HARADA, T, WATANABE, M, HIGUCHI, S, KOJIMA, H, KAMIMURA, T, ASAKURA, H

“…Chronic hepatitis, cirrhosis, and hepatocellular carcinoma are the accepted sequelae of chronic hepatitis C virus (HCV) infection. However, the real natural…”
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A structural protein of hepatitis C virus expressed in E. coli facilitates accurate detection of hepatitis C virus by Muraiso, K, Hijikata, M, Ohkoshi, S, Cho, M J, Kikuchi, M, Kato, N, Shimotohno, K

“…A putative core protein derived from hepatitis C virus was expressed in E. coli. More than 5% of the total protein expressed in the bacteria after induction by…”
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Virus Isolate‐specific Antibodies against Hypervariable Region 1 of the Hepatitis C Virus Second Envelope Protein, gp70 by Kato, Nobuyuki, Nakazawa, Takahide, Ootsuyama, Yuko, Sugiyama, Kazuo, Ohkoshi, Showgo, Shimotohno, Kunitada

“…Hypervariable region 1 (HVR1), located in the N‐terminal region of a putative second envelope glycoprotein (gp70) of hepatitis C virus (HCV), contains…”
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Epidemiologic survey and genetic analysis of endemic hepatitis C virus infection in a Japanese town with a high prevalence of hepatitis B virus carriers by Tawaraya, H, Ohkoshi, S, Kuwana, K, Watanabe, M, Kamimura, T, Asakura, H

“…Mass screening for hepatitis C virus antibody was carried out in 875 inhabitants (313 men and 562 women) of a town in Japan with a high rate of hepatitis B…”
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Detection of Hepatitis C Virus RNA in Sera and Liver Tissues of Non‐A, Non‐B Hepatitis Patients Using the Polymerase Chain Reaction by Ohkoshi, Showgo, Kato, Nobuyuki, Kinoshita, Tomohiro, Hijikata, Makoto, Ohtsuyama, Yuko, Okazaki, Nobuo, Ohkura, Hisanao, Hirohashi, Setsuo, Honma, Akira, Ozaki, Toshihiko, Yoshikawa, Akira, Kojima, Hideo, Asakura, Hitoshi, Shimotohno, Kunitada

“…Sera obtained from patients with non‐A, non‐B hepatitis were examined for the presence of hepatitis C virus (HCV) genome by using the reverse…”
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Serodiagnostic Assay of Hepatitis C Virus Infection Using Viral Proteins Expressed in Escherichia coli by Mori, Shigehisa, Ohkoshi, Showgo, Hijikata, Makoto, Kato, Nobuyuki, Shimotohno, Kunitada

“…Infection with hepatitis C virus (HCV) was analyzed by an enzyme‐linked immunosorbent assay based on recombinant viral proteins encoded by regions of the…”
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Sequence analysis of the proximal promoter region of the human alpha-fetoprotein gene in hepatocellular carcinoma by Igarashi, K, Aoyagi, Y, Ohkoshi, S, Yokota, T, Mori, S, Suda, T, Kamimura, T, Asakura, H

“…We have examined whether or not mutations exist in the proximal promoter region of the human alpha-fetoprotein (AFP) gene in the hepatocellular carcinoma (HCC)…”
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A Structural Protein Encoded by the 5′ Region of the Hepatitis C Virus Genome Efficiently Detects Viral Infection by Kato, Nobuyuki, Hijikata, Makoto, Ootsuyama, Yuko, Nakagawa, Masanori, Ohkoshi, Showgo, Shimotohno, Kunitada

“…A structural region of the hepatitis C virus genome was molecularly cloned. A protein expressed in vitro by transcription followed by translation was…”
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