Search Results - "OHKAWARA, Akira"

High Expression of Macrophage Migration Inhibitory Factor in Human Melanoma Cells and Its Role in Tumor Cell Growth and Angiogenesis by Shimizu, Tadamichi, Abe, Riichiro, Nakamura, Hideki, Ohkawara, Akira, Suzuki, Masaki, Nishihira, Jun

“…Macrophage migration inhibitory factor (MIF) is known to function as a cytokine, hormone, and glucocorticoid-induced immunoregulator. In this study, we…”
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A survey of psoriasis patients in Japan from 1982 to 2001 by Kawada, Akira, Tezuka, Tadashi, Nakamizo, Yoshio, Kimura, Hideto, Nakagawa, Hidemi, Ohkido, Muneo, Ozawa, Akira, Ohkawara, Akira, Kobayashi, Hitoshi, Harada, Shotaro, Igarashi, Atsuyuki

“…The Japanese Society for Psoriasis Research has conducted an annual survey of psoriasis patients in Japan from 1982 to 2001. To perform the epidemiological…”
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Analysis of psoriatic patients registered in Asahikawa Medical College Hospital from 1983 to 2007 by TAKAHASHI, Hidetoshi, TAKAHASHI, Ichiro, TSUJI, Hitomi, IBE, Masaki, KINOUCHI, Motoshi, HASHIMOTO, Yoshio, ISHIDA-YAMAMOTO, Akemi, MATSUO, Shinobu, OHKUMA, Noritaka, OHKAWARA, Akira, IIZUKA, Hajime

“…Psoriasis is a chronic inflammatory skin disease, which has been increasing during the last 50 years in Japan. The aim of the present study is to analyze…”
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Enhancement of macrophage migration inhibitory factor (MIF) expression in injured epidermis and cultured fibroblasts by Abe, Riichiro, Shimizu, Tadamichi, Ohkawara, Akira, Nishihira, Jun

“…After the cDNA of human macrophage migration inhibitory factor (MIF) was cloned in 1989, this protein has been re-evaluated as a pro-inflammatory cytokine,…”
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Identification of macrophage migration inhibitory factor (MIF) in human skin and its immunohistochemical localization by Shimizu, Tadamichi, Ohkawara, Akira, Nishihira, Jun, Sakamoto, Wataru

“…The presence and tissue localization of macrophage migration inhibitory factor (MIF) in human skin were examined. Reverse transcription-polymerase chain…”
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Increased production of macrophage migration inhibitory factor by PBMCs of atopic dermatitis by Shimizu, Tadamichi, Abe, Riichiro, Ohkawara, Akira, Nishihira, Jun

“…Background: Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disorder. The underlying cause of AD is multifactorial, and several cytokines are…”
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Ultraviolet B Radiation Upregulates the Production of Macrophage Migration Inhibitory Factor (MIF) in Human Epidermal Keratinocytes by Shimizu, Tadamichi, Abe, Riichiro, Ohkawara, Akira, Nishihira, Jun

“…Human epidermal cells are capable of secreting various cytokines with immunologic, inflammatory, and proliferative properties. In a previous study, by reverse…”
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Macrophage Migration Inhibitory Factor Is an Essential Immunoregulatory Cytokine in Atopic Dermatitis by Shimizu, Tadamichi, Abe, Riichiro, Ohkawara, Akira, Mizue, Yuka, Nishihira, Jun

“…Macrophage migration inhibitory factor (MIF) is one of the immunoregulatory cytokines involved in T-cell activation and delayed-type hypersensitivity. To…”
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Treatments of Generalized Pustular Psoriasis: A Multicenter Study in Japan by Ozawa, Akira, Ohkido, Muneo, Haruki, Yasuo, Kobayashi, Hitoshi, Ohkawara, Akira, Ohno, Yoshiyuki, Inaba, Yutaka, Ogawa, Hideoki

“…This study analyzed data from treatments of 385 cases of generalized pustular psoriasis (GPP) from 325 hospitals in Japan. Retinoid treatment was effective in…”
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H2 histamine receptor-mediated increase in intracellular Ca2+ in cultured human keratinocytes by Koizumi, H, Ohkawara, A

“…Histamine is present in the epidermis in intracellular and extracellular area and is released from mast cells and keratinocytes in the early stage of…”
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Spindle cell angiosarcoma following irradiation therapy for cervical carcinoma by Kiyohara, Takahiro, Kumakiri, Masanobu, Kobayashi, Hitoshi, Itoh, Kei, Lao, Li-Min, Ohkawara, Akira, Nakamura, Hideki

“…Background:  Angiosarcomas arise in the scalp and face in the elderly, in association with chronic lymphedema (Stewart–Treves syndrome), and in irradiated…”
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1,25-Dihydroxyvitamin D 3 and a new analogue, 22-oxacalcitriol, modulate proliferation and interleukin-8 secretion of normal human keratinocytes by Koizumi, Hiroko, Kaplan, Alex, Shimizu, Tadamichi, Ohkawara, Akira

“…Vitamin D 3 is a new therapeutic agent for psoriasis. Hyperproliferation of epidermis and over-secretion of IL-8 by keratinocytes are the characteristic…”
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Postoperative Alveolar Hydatid Disease with Cutaneous‐Subcutaneous Involvement by Ambo, Midori, Adachi, Kouichi, Ohkawara, Akira

“…The first Japanese case of alveolar hydatid disease with cutaneous‐subcutaneous lesions is reported. The patient, a 58‐year‐old man who developed an indurated…”
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Autoantigens for IgA Anti-Intercellular Antibodies of Intercellular IgA Vesiculopustular Dermatosis by Ebihara, Tamotsu, Hashimoto, Takashi, Iwatsuki, Keiji, Takigawa, Masahiro, Ando, Masaaki, Ohkawara, Akira, Nishikawa, Takeji

“…A new disease characterized by the presence of in vivo bound and/or circulating IgA anti-intercellular (IC) antibodies has recently been identified. We propose…”
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The effects of cyclosporin A and FK506 on proliferation and IL-8 production of cultured human keratinocytes by Kaplan, Alexander, Matsue, Hiroyuki, Shibaki, Akihiko, Kawashima, Toshimitsu, Kobayashi, Hitoshi, Ohkawara, Akira

“…The present study was conducted to determine whether cyclosporin A (CsA) and FK506 could be effective in inhibiting the proliferation and cytokine secretion of…”
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Specific Cutaneous Lesions of the Scalp in Myelodysplastic Syndrome with Deletion of 20q by Namba, Yumi, Koizumi, Hiroko, Nakamura, Hideki, Tarumi, Takashi, Sawada, Ken'ichi, Ohkawara, Akira

“…We reported a specific skin lesion on the scalp in a patient with myelodysplastic syndrome (MDS), treated as refractory anemia with excess of blasts (RAEB)…”
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Papillary Eccrine Adenoma with a Pomegranate‐like Appearance by Ambo, Midori, Kumakiri, Masanobu, Kobayashi, Hitoshi, Ohkawara, Akira

“…Papillary eccrine adenoma (PEA) is a rare cutaneous tumor which histopathologically presents numerous intradermal tubular structures with inward papillary…”
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Immunohistological detection of proliferating cells in normal and psoriatic epidermis using Ki-67 monoclonal antibody by Ando, M, Kawashima, T, Kobayashi, H, Ohkawara, A

“…Ki-67 monoclonal antibody (mAb) has been suggested to react only with proliferating cells. In order to study epidermal proliferating cells, immunohistological…”
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Substance P induces inositol 1,4,5-trisphosphate and intracellular free calcium increase in cultured normal human epidermal keratinocytes by Koizumi, H, Yasui, C, Fukaya, T, Ueda, T, Ohkawara, A

“…Substance P is a neuropeptide which is present in peripheral C nerve endings and released from them. Free nerve endings of C nerve are present in human…”
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Identification of mRNA-rich keratinocytes in the basal/suprabasal layers of psoriatic skin by Yokota, K, Matsue, H, Shibaki, A, Kawashima, T, Kobayashi, H, Ohkawara, A

“…In this study, we examined the relative amounts of mRNA expressed in normal versus psoriatic epidermis, using in situ hybridization with a biotinylated…”
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