Search Results - "OHIRA, Takayuki"

Precursors of tRNAs are stabilized by methylguanosine cap structures by Ohira, Takayuki, Suzuki, Tsutomu

“…MS analysis of yeast transfer RNA precursors (pre-tRNAs) isolated at different stages of tRNA processing and maturation reveals the presence of 5′-terminal…”
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Retrograde nuclear import of tRNA precursors is required for modified base biogenesis in yeast by Ohira, Takayuki, Suzuki, Tsutomu

“…The retrograde movement of tRNAs from the cytoplasm to the nucleus occurs constitutively in eukaryotic cells but its functional significance remains unclear…”
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A single m6A modification in U6 snRNA diversifies exon sequence at the 5’ splice site by Ishigami, Yuma, Ohira, Takayuki, Isokawa, Yui, Suzuki, Yutaka, Suzuki, Tsutomu

“…N 6 -methyladenosine (m 6 A) is a modification that plays pivotal roles in RNA metabolism and function, although its functions in spliceosomal U6 snRNA remain…”
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A VEGF receptor vaccine demonstrates preliminary efficacy in neurofibromatosis type 2 by Tamura, Ryota, Fujioka, Masato, Morimoto, Yukina, Ohara, Kentaro, Kosugi, Kenzo, Oishi, Yumiko, Sato, Mizuto, Ueda, Ryo, Fujiwara, Hirokazu, Hikichi, Tetsuro, Noji, Shinobu, Oishi, Naoki, Ogawa, Kaoru, Kawakami, Yutaka, Ohira, Takayuki, Yoshida, Kazunari, Toda, Masahiro

“…The anti-VEGF antibody bevacizumab has shown efficacy for the treatment of neurofibromatosis type 2 (NF2). Theoretically, vascular endothelial growth factor…”
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Reversible RNA phosphorylation stabilizes tRNA for cellular thermotolerance by Ohira, Takayuki, Minowa, Keiichi, Sugiyama, Kei, Yamashita, Seisuke, Sakaguchi, Yuriko, Miyauchi, Kenjyo, Noguchi, Ryo, Kaneko, Akira, Orita, Izumi, Fukui, Toshiaki, Tomita, Kozo, Suzuki, Tsutomu

“…Post-transcriptional modifications have critical roles in tRNA stability and function 1 – 4 . In thermophiles, tRNAs are heavily modified to maintain their…”
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Cryo-EM structure of the transposon-associated TnpB enzyme by Nakagawa, Ryoya, Hirano, Hisato, Omura, Satoshi N., Nety, Suchita, Kannan, Soumya, Altae-Tran, Han, Yao, Xiao, Sakaguchi, Yuriko, Ohira, Takayuki, Wu, Wen Y., Nakayama, Hiroshi, Shuto, Yutaro, Tanaka, Tatsuki, Sano, Fumiya K., Kusakizako, Tsukasa, Kise, Yoshiaki, Itoh, Yuzuru, Dohmae, Naoshi, van der Oost, John, Suzuki, Tsutomu, Zhang, Feng, Nureki, Osamu

“…The class 2 type V CRISPR effector Cas12 is thought to have evolved from the IS200/IS605 superfamily of transposon-associated TnpB proteins 1 . Recent studies…”
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Effects of transcranial stimulating electrode montages over the head for lower-extremity transcranial motor evoked potential monitoring by Tomio, Ryosuke, Akiyama, Takenori, Ohira, Takayuki, Yoshida, Kazunari

“…OBJECTIVE The aim of this study was to determine the most effective electrode montage to elicit lower-extremity transcranial motor evoked potentials (LE-tMEPs)…”
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Functional redundancy of ubiquitin-like sulfur-carrier proteins facilitates flexible, efficient sulfur utilization in the primordial archaeon Thermococcus kodakarensis by Hidese, Ryota, Ohira, Takayuki, Sakakibara, Satsuki, Suzuki, Tsutomu, Shigi, Naoki, Fujiwara, Shinsuke

“…Ubiquitin-like proteins (Ubls) in eukaryotes and bacteria mediate sulfur transfer for the biosynthesis of sulfur-containing biomolecules and form conjugates…”
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Repetitive transcranial magnetic stimulation once a week induces sustainable long-term relief of central poststroke pain by Kobayashi, Masahito, Fujimaki, Takamitsu, Mihara, Ban, Ohira, Takayuki

“…Central poststroke pain is a serious problem for some patients after stroke. Repetitive transcranial magnetic stimulation (rTMS) has been reported to relieve…”
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ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications by Kawarada, Layla, Suzuki, Takeo, Ohira, Takayuki, Hirata, Shoji, Miyauchi, Kenjyo, Suzuki, Tsutomu

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Changes in intracortical inhibition and clinical symptoms after STN-DBS in Parkinson’s disease by Kobayashi, Masahito, Ohira, Takayuki, Mihara, Ban, Fujimaki, Takamitsu

“…Highlights • Deep brain stimulation (DBS) does not restore intracortical inhibition in Parkinson’s disease (PD). • During DBS-OFF, short-interval intracortical…”
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The impact of several craniotomies on transcranial motor evoked potential monitoring during neurosurgery by Tomio, Ryosuke, Akiyama, Takenori, Toda, Masahiro, Ohira, Takayuki, Yoshida, Kazunari

“…OBJECTIVE Transcranial motor evoked potential (tMEP) monitoring is popular in neurosurgery; however, the accuracy of tMEP can be impaired by craniotomy. Each…”
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Author Correction: A VEGF receptor vaccine demonstrates preliminary efficacy in neurofibromatosis type 2 by Tamura, Ryota, Fujioka, Masato, Morimoto, Yukina, Ohara, Kentaro, Kosugi, Kenzo, Oishi, Yumiko, Sato, Mizuto, Ueda, Ryo, Fujiwara, Hirokazu, Hikichi, Tetsuro, Noji, Shinobu, Oishi, Naoki, Ogawa, Kaoru, Kawakami, Yutaka, Ohira, Takayuki, Yoshida, Kazunari, Toda, Masahiro

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Visualization of the electric field evoked by transcranial electric stimulation during a craniotomy using the finite element method by Tomio, Ryosuke, Akiyama, Takenori, Horikoshi, Tomo, Ohira, Takayuki, Yoshida, Kazunari

“…•Influences of craniotomy in intraoperative tMEP monitoring were numerically estimated.•The electric field in the brain radiates out from the cortex just below…”
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Distinct tRNA modifications in the thermo-acidophilic archaeon, Thermoplasma acidophilum by Tomikawa, Chie, Ohira, Takayuki, Inoue, Yasushi, Kawamura, Takuya, Yamagishi, Akihiko, Suzuki, Tsutomu, Hori, Hiroyuki

“…•Thermoplasma acidophilum tRNALeu contains distinct modified nucleotides.•7-Methylguanine was found at novel position 49 in tRNALeu.•Archaeosines were found at…”
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Usefulness of facial nerve monitoring for confirmation of greater superficial petrosal nerve in anterior transpetrosal approach by Tomio, Ryosuke, Akiyama, Takenori, Ohira, Takayuki, Horikoshi, Tomo, Yoshida, Kazunari

“…Introduction The greater superficial petrosal nerve (GSPN) is especially important in anterior transpetrosal approach (ATPA) as the most reliable superficial…”
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LRPPRC/SLIRP suppresses PNPase-mediated mRNA decay and promotes polyadenylation in human mitochondria by Chujo, Takeshi, Ohira, Takayuki, Sakaguchi, Yuriko, Goshima, Naoki, Nomura, Nobuo, Nagao, Asuteka, Suzuki, Tsutomu

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Neuroendoscopic biopsy and the treatment of tumor-associated hydrocephalus of the ventricular and paraventricular region in pediatric patients: a nationwide study in Japan by Miwa, Tomoru, Hayashi, Nakamasa, Endo, Shunro, Ohira, Takayuki

“…A neuroendoscopic biopsy is a minimally invasive and useful procedure for the diagnosis and initial management of tumor-associated hydrocephalus. We describe…”
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Association of Hydrophobic Carboxyl-Terminal Dendrimers with Lymph Node-Resident Lymphocytes by Nishimoto, Yutaka, Nishio, Misaki, Nagashima, Shu, Nakajima, Kohei, Ohira, Takayuki, Nakai, Shinya, Nakase, Ikuhiko, Higashikawa, Kei, Kuge, Yuji, Matsumoto, Akikazu, Ogawa, Mikako, Kojima, Chie

“…Delivery systems to lymph node-resident T cells around tumor tissues are essential for cancer immunotherapy, in order to boost the immune responses. We…”
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Structural and functional characterization of the TYW3/Taw3 class of SAM-dependent methyltransferases by Currie, Mark A, Brown, Greg, Wong, Andrew, Ohira, Takayuki, Sugiyama, Kei, Suzuki, Tsutomu, Yakunin, Alexander F, Jia, Zongchao

“…-adenosylmethionine (SAM)-dependent methyltransferases regulate a wide range of biological processes through the modification of proteins, nucleic acids,…”
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