CLINICAL STUDIES ON BACAMPICILLIN IN URINARY TRACT INFECTIONS
1) Blood concentration Bacampicillin in blood, after the oral administration of 500mg, reached an average peak 12.0μg/ml after one hour, and the concentration was still 0.4μg/ml after 6 hours. 2) Urinary excretion In the same cases in which the blood concentraiton was measured, 78.0% of the dose was...
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| Published in: | CHEMOTHERAPY Vol. 27; no. Supplement4; pp. 271 - 279 |
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| Main Authors: | , , , |
| Format: | Journal Article |
| Language: | Japanese |
| Published: |
Japanese Society of Chemotherapy
25-05-1979
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| Online Access: | Get full text |
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| Summary: | 1) Blood concentration Bacampicillin in blood, after the oral administration of 500mg, reached an average peak 12.0μg/ml after one hour, and the concentration was still 0.4μg/ml after 6 hours. 2) Urinary excretion In the same cases in which the blood concentraiton was measured, 78.0% of the dose was recovered on the average from 8 hour urine. 3) Clinical results In 17 cases of acute simple cystitis, and 34 cases of chronic complicated urinary tract infection, totaling 51 cases, excellent effect was obtained in 26, good effect in 11, and no effect in 14, giving the effectiveness of 72.6%. 4) Among 54 cases including 3 cases with measurement of blood concentration, no noteworthy side effects were observed. |
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| ISSN: | 0009-3165 1884-5894 |
| DOI: | 10.11250/chemotherapy1953.27.Supplement4_271 |