Search Results - "OH, Sangkon"

Implication of TIGIT+ human memory B cells in immune regulation by Hasan, Md Mahmudul, Nair, Sumi Sukumaran, O’Leary, Jacqueline G., Thompson-Snipes, LuAnn, Nyarige, Verah, Wang, Junwen, Park, Walter, Stegall, Mark, Heilman, Raymond, Klintmalm, Goran B., Joo, HyeMee, Oh, SangKon

“…Regulatory B cells (Bregs) contribute to immune regulation. However, the mechanisms of action of Bregs remain elusive. Here, we report that T cell…”
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Merging Components in Linear Gaussian Cluster-Weighted Models by Oh, Sangkon, Seo, Byungtae

“…Cluster-weighted models (CWMs) are useful tools for identifying latent functional relationships between response variables and covariates. However, owing to…”
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Semiparametric mixture of linear regressions with nonparametric Gaussian scale mixture errors by Oh, Sangkon, Seo, Byungtae

“…In finite mixture of regression models, normal assumption for the errors of each regression component is typically adopted. Though this common assumption is…”
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Signaling Cascade through DC-ASGPR Induces Transcriptionally Active CREB for IL-10 Induction and Immune Regulation by Gu, Chao, Wang, Lei, Zurawski, Sandra, Oh, SangKon

“…The types and magnitude of Ag-specific immune responses can be determined by the functional plasticity of dendritic cells (DCs). However, how DCs display…”
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Chemoradiotherapy-induced upregulation of PD-1 antagonizes immunity to HPV-related oropharyngeal cancer by Parikh, Falguni, Duluc, Dorothée, Imai, Naoko, Clark, Amelia, Misiukiewicz, Krzys, Bonomi, Marcello, Gupta, Vishal, Patsias, Alexis, Parides, Michael, Demicco, Elizabeth G, Zhang, David Y, Kim-Schulze, Seunghee, Kao, Johnny, Gnjatic, Sacha, Oh, Sangkon, Posner, Marshall R, Sikora, Andrew G

“…While viral antigens in human papillomavirus (HPV)-related oropharyngeal cancer (HPVOPC) are attractive targets for immunotherapy, the effects of existing…”
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Whole blood transcriptional variations between responders and non‐responders in asthma patients receiving omalizumab by Upchurch, Katherine, Wiest, Matthew, Cardenas, Jacob, Skinner, Jason, Nattami, Durgha, Lanier, Bobby, Millard, Mark, Joo, HyeMee, Turner, Jacob, Oh, SangKon

“…Background Anti‐IgE (omalizumab) has been used for the treatment of moderate‐to‐severe asthma that is not controlled by inhaled steroids. Despite its success,…”
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Harnessing human dendritic cell subsets for medicine by Ueno, Hideki, Schmitt, Nathalie, Klechevsky, Eynav, Pedroza-Gonzalez, Alexander, Matsui, Toshimichi, Zurawski, Gerard, Oh, SangKon, Fay, Joseph, Pascual, Virginia, Banchereau, Jacques, Palucka, Karolina

“…Immunity results from a complex interplay between the antigen‐non‐specific innate immune system and the antigen‐specific adaptive immune system. The cells and…”
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Dectin-1 Controls TSLP-Induced Th2 Response by Regulating STAT3, STAT6, and p50-RelB Activities in Dendritic Cells by Gu, Chao, Upchurch, Katherine, Horton, Joshua, Wiest, Mathew, Zurawski, Sandra, Millard, Mark, Kane, Robert R, Joo, HyeMee, Miller, Lisa A, Oh, SangKon

“…The epithelium-associated cytokine thymic stromal lymphopoietin (TSLP) can induce OX40L and CCL17 expression by myeloid dendritic cells (mDCs), which…”
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Differential expression of nuclear hormone receptors by dendritic cell subsets in human vaginal mucosa and skin by Joo, HyeMee, Gu, Chao, Wiest, Matthew, Duluc, Dorothee, Fernandez, Emyly, Nyarige, Verah, Yi, Johnny, Oh, SangKon

“…Nuclear hormone receptors (NHRs) expressed by dendritic cells (DCs), the major immune inducers and regulators, could play important roles in host immunity…”
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Targeting concatenated HIV antigens to human CD40 expands a broad repertoire of multifunctional CD4+ and CD8+ T cells by FLAMAR, Anne-Laure, YAMING XUE, ZURAWSKI, Sandra M, MONTES, Monica, KING, Bryan, SLOAN, Louis, SANGKON OH, BANCHEREAU, Jacques, LEVY, Yves, ZURAWSKI, Gerard

“…Targeting HIV antigens directly to dendritic cells using monoclonal antibodies against cell-surface receptors has been shown to evoke potent cellular immunity…”
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Macrophages induce differentiation of plasma cells through CXCL10/IP-10 by Xu, Wei, Joo, HyeMee, Clayton, Sandra, Dullaers, Melissa, Herve, Marie-Cecile, Blankenship, Derek, De La Morena, Maria Teresa, Balderas, Robert, Picard, Capucine, Casanova, Jean-Laurent, Pascual, Virginia, Oh, SangKon, Banchereau, Jacques

“…In tonsils, CD138(+) plasma cells (PCs) are surrounded by CD163(+) resident macrophages (Ms). We show here that human Ms (isolated from tonsils or generated…”
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Disruption of endosomal trafficking with EGA alters TLR9 cytokine response in human plasmacytoid dendritic cells by Wiest, Matthew J, Gu, Chao, Ham, Hyoungjun, Gorvel, Laurent, Keddis, Mira T, Griffing, Leroy W, Joo, HyeMee, Gorvel, Jean-Pierre, Billadeau, Daniel D, Oh, SangKon

“…Plasmacytoid dendritic cells (pDCs) exhibit bifurcated cytokine responses to TLR9 agonists, an IRF7-mediated type 1 IFN response or a pro-inflammatory cytokine…”
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Endosomal trafficking inhibitor EGA can control TLR7-mediated IFNα expression by human plasmacytoid dendritic cells by Wiest, Matthew J, Baert, Laurie, Gu, Chao, Gayler, Kevin M, Ham, Hyoungjun, Gorvel, Laurent, Keddis, Mira T, Griffing, Leroy W, Joo, HyeMee, Gorvel, Jean-Pierre, Billadeau, Daniel D, Kane, Robert R, Oh, SangKon

“…Plasmacytoid dendritic cells (pDC) are the major producer of type 1 IFN in response to TLR7 agonists. Aberrant TLR7 activation and type 1 IFN expression by…”
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IL-15 as a mediator of CD4⁺ help for CD8⁺ T cell longevity and avoidance of TRAIL-mediated apoptosis by Oh, SangKon, Perera, Liyanage P, Terabe, Masaki, Ni, Ling, Waldmann, Thomas A, Berzofsky, Jay A

“…CD4⁺ helper T cells contribute to the induction and maintenance of antigen-specific CD8⁺ T cells. Their absence results in short-lived antigen-specific CD8⁺ T…”
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Functional Specialty of CD40 and Dendritic Cell Surface Lectins for Exogenous Antigen Presentation to CD8+ and CD4+ T Cells by Yin, Wenjie, Gorvel, Laurent, Zurawski, Sandra, Li, Dapeng, Ni, Ling, Duluc, Dorothée, Upchurch, Katherine, Kim, JongRok, Gu, Chao, Ouedraogo, Richard, Wang, Zhiqing, Xue, Yaming, Joo, HyeMee, Gorvel, Jean-Pierre, Zurawski, Gerard, Oh, SangKon

“…Dendritic cells (DCs) are major antigen-presenting cells that can efficiently prime and cross-prime antigen-specific T cells. Delivering antigen to DCs via…”
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Immunomodulatory properties of Brucella melitensis lipopolysaccharide determinants on mouse dendritic cells in vitro and in vivo by Zhao, Yun, Hanniffy, Sean, Arce-Gorvel, Vilma, Conde-Alvarez, Raquel, Oh, SangKon, Moriyón, Ignacio, Mémet, Sylvie, Gorvel, Jean-Pierre

“…The lipopolysaccharide (LPS) is a major virulence factor of Brucella, a facultative intracellular pathogenic Gram-negative bacterium. Brucella LPS exhibits a…”
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Lipopolysaccharides with acylation defects potentiate TLR4 signaling and shape T cell responses by Martirosyan, Anna, Ohne, Yoichiro, Degos, Clara, Gorvel, Laurent, Moriyón, Ignacio, Oh, Sangkon, Gorvel, Jean-Pierre

“…Lipopolysaccharides or endotoxins are components of Gram-negative enterobacteria that cause septic shock in mammals. However, a LPS carrying hexa-acyl lipid A…”
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Brucella β 1,2 cyclic glucan is an activator of human and mouse dendritic cells by Martirosyan, Anna, Pérez-Gutierrez, Camino, Banchereau, Romain, Dutartre, Hélène, Lecine, Patrick, Dullaers, Melissa, Mello, Marielle, Salcedo, Suzana Pinto, Muller, Alexandre, Leserman, Lee, Levy, Yves, Zurawski, Gerard, Zurawski, Sandy, Moreno, Edgardo, Moriyón, Ignacio, Klechevsky, Eynav, Banchereau, Jacques, Oh, Sangkon, Gorvel, Jean-Pierre

“…Bacterial cyclic glucans are glucose polymers that concentrate within the periplasm of alpha-proteobacteria. These molecules are necessary to maintain the…”
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IL-15/IL-15Rα-Mediated Avidity Maturation of Memory CD8+ T Cells by Oh, SangKon, Perera, Liyanage P., Burke, Donald S., Waldmann, Thomas A., Berzofsky, Jay A.

“…T cell avidity is critical to viral clearance, but mechanisms of CD8+ T cell avidity maturation are poorly understood. Here, we find that IL-15 mediates two…”
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Clinical implications of CD4 + T cell subsets in adult atopic asthma patients by Wiest, Matthew, Upchurch, Katherine, Yin, Wenjie, Ellis, Jerome, Xue, Yaming, Lanier, Bobby, Millard, Mark, Joo, HyeMee, Oh, SangKon

“…T cells play a central role in chronic inflammation in asthma. However, the roles of individual subsets of T cells in the pathology of asthma in patients…”
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