Search Results - "OGURA, Syozo"

新規頻尿・尿失禁治療剤 (±)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydtoxy-2-phenylacetate monohydrochloride monohydrate (NS-21) の変異原性試験 by 大塚, 雅則, 梶原, 美次, 安心院, 祥三, 島崎, 博子, 菊野, 秩, 小椋, 正造, 稲井, 恒彦, 柿本, 敬次郎, 田村, 博信, 渡辺, 正孝, 鷲見, 信好

“…NS-21の細菌を用いる復帰突然変異試験, 哺乳類培養細胞を用いる染色体異常試験およびマウスを用いる小核試験を実施し, 以下の成績を得た。細菌を用いる復帰突然変異試験では, サルモネラ菌のTA100, TA1535, TA98およびTA1537ならびに大腸菌のWP2uvrAを用いて,…”
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MUTAGENICITY STUDIES OF (±)-4-DIETHYLAMINO-1, 1, -DIMETHYLBUT-2-YN-1-YL 2-CYCLHOEXYL-2-HYDROXY-2-PHENYLACETATE MONOHYDROCHLORIDE MONOHYDRATE (NS-21), A NOVEL DRUG FOR URINARY FREQUENCY AND INCONTINENCE by OTSUKA, Masanori, KAJIWARA, Yoshitsugu, AJIMI, Syozo, SHIMAZAKI, Hiroko, KIKUNO, Tsukasa, OGURA, Syozo, INAI, Tsunehiko, KAKIMOTO, Keijiro, TAMURA, Hironobu, WATANABE, Masataka, SUMI, Nobuyoshi

“…The mutagenicity of (±)-4-diethylamino-1, 1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a new drug for…”
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DNA fingerprint analysis in chemically mutagenized Chinese hamster lung cells by Kikuno, Tsukasa, Honma, Masamitsu, Ogura, Syozo, Mizusawa, Hiroshi, Hayashi, Makoto, Sofuni, Toshio

“…Using a multi locus minisatellite Per-6 DNA probe, we performed DNA fingerprint analysis. Chinese hamster lung (CHL) cells were treated with six model…”
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Mutagenicity studies of (±)-4-diethylamino-1,1,-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a novel drug for urinary frequency and incontinence by OTSUKA, M, KAJIWARA, Y, SUMI, N, AJIMI, S, SHIMAZAKI, H, KIKUNO, T, OGURA, S, INAI, T, KAKIMOTO, K, TAMURA, H, WATANABE, M

“…The mutagenicity of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a new drug for…”
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