Search Results - "OGUCHI, YOSHIHISA"

Visual prognosis better in eyes with less severe reduction of visual acuity one year after onset of Leber hereditary optic neuropathy caused by the 11,778 mutation by Mashima, Yukihiko, Kigasawa, Kazuteru, Shinoda, Kei, Wakakura, Masato, Oguchi, Yoshihisa

“…Patients with Leber hereditary optic neuropathy (LHON) have a progressive decrease of their visual acuity which can deteriorate to <0.1. Some patients can have…”
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Vitreous concentrations of triamcinolone acetonide in human eyes after intravitreal or subtenon injection by Inoue, Makoto, Takeda, Kayoko, Morita, Kunihiko, Yamada, Masakazu, Tanigawara, Yusuke, Oguchi, Yoshihisa

“…To compare vitreous concentrations of triamcinolone acetonide (TA) achieved by prior therapeutic intravitreal and subtenon injections. Interventional case…”
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Mapping Cone- and Rod-Induced Retinal Responsiveness in Macaque Retina by Optical Imaging by Tsunoda, Kazushige, Oguchi, Yoshihisa, Hanazono, Gen, Tanifuji, Manabu

“…To map the distribution of cone- or rod-induced retinal responsiveness by optical imaging from macaque retina. The light reflectance changes in the posterior…”
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Production and Activation of Matrix Metalloproteinase-2 in Proliferative Diabetic Retinopathy by Noda, Kousuke, Ishida, Susumu, Inoue, Makoto, Obata, Ken-ichi, Oguchi, Yoshihisa, Okada, Yasunori, Ikeda, Eiji

“…To investigate the matrix metalloproteinase (MMP) species and their activation associated with the pathogenesis of proliferative diabetic retinopathy (PDR)…”
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A Novel Myosin-like Protein (Myocilin) Expressed in the Connecting Cilium of the Photoreceptor: Molecular Cloning, Tissue Expression, and Chromosomal Mapping by Kubota, Ryo, Noda, Setsuko, Wang, Yimin, Minoshima, Shinsei, Asakawa, Shuichi, Kudoh, Jun, Mashima, Yukihiko, Oguchi, Yoshihisa, Shimizu, Nobuyoshi

“…We have isolated a human cDNA clone encoding a novel acidic protein of MW 55,000 that we designated “myocilin” since it has homology to myosin and is localized…”
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A homozygous 1-base pair deletion in the arrestin gene is a frequent cause of Oguchi disease in Japanese by Fuchs, Sigrid, Nakazawa, Mitsuru, Maw, Marion, Tamai, Makoto, Oguchi, Yoshihisa, Gal, Andreas

“…Oguchi disease is a rare autosomal recessive form of congenital stationary night blindness with all other visual functions, including visual acuity, visual…”
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Hypoxia Induces the Expression of Membrane-Type 1 Matrix Metalloproteinase in Retinal Glial Cells by Noda, Kousuke, Ishida, Susumu, Shinoda, Hajime, Koto, Takashi, Aoki, Takanori, Tsubota, Kazuo, Oguchi, Yoshihisa, Okada, Yasunori, Ikeda, Eiji

“…Fibrovascular tissue formation in diabetic retinopathy necessitates not only angiogenic activity but also proteolytic activity, which is at least in part…”
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Disposable eyelid-warming device for the treatment of meibomian gland dysfunction by Mori, Asako, Shimazaki, Jun, Shimmura, Shigeto, Fujishima, Hiroshi, Oguchi, Yoshihisa, Tsubota, Kazuo

“…To assess the clinical efficacy of a newly developed disposable eyelid-warming device (Eye Warmer) for the treatment of meibomian gland dysfunction (MGD). The…”
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Visualization of gaseous monoxide reception by soluble guanylate cyclase in the rat retina by Kajimura, Mayumi, Shimoyama, Masaru, Tsuyama, Shingo, Suzuki, Tsuneharu, Kozaki, Shunji, Takenaka, Shigeo, Tsubota, Kazuo, Oguchi, Yoshihisa, Suematsu, Makoto

“…Immunohistochemistry using novel monoclonal antibodies (mAbs) allowed us to uncover tissue activities of soluble guanylate cyclase (sGC) fine tuned by NO and…”
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Downregulation of STAT3 activation is required for presumptive rod photoreceptor cells to differentiate in the postnatal retina by Ozawa, Yoko, Nakao, Keiko, Shimazaki, Takuya, Takeda, Junji, Akira, Shizuo, Ishihara, Katsuhiko, Hirano, Toshio, Oguchi, Yoshihisa, Okano, Hideyuki

“…Ciliary neurotrophic factor (CNTF) has been known to inhibit the differentiation of presumptive rod photoreceptor cells; however, the underlying mechanisms…”
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Discordance Between Subjective Perimetric Visual Fields and Objective Multifocal Visual Evoked Potential-Determined Visual Fields in Patients With Hemianopsia by Watanabe, Ken, MD, Shinoda, Kei, MD, Kimura, Itaru, MD, Mashima, Yukihiko, MD, Oguchi, Yoshihisa, MD, Ohde, Hisao, MD

“…Purpose To investigate the concordance between subjectively and objectively acquired visual fields in patients with subjectively determined hemianopsia. Design…”
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Macular hole retinal detachment in highly myopic eyes: ultrastructure of surgically removed epiretinal membrane and clinicopathologic correlation by Ishida, S, Yamazaki, K, Shinoda, K, Kawashima, S, Oguchi, Y

“…To elucidate the pathogenesis of macular hole retinal detachment (RD) in highly myopic eyes by investigating the ultrastructure of surgically removed…”
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Retinal blood flow in the macular area before and after scleral buckling procedures for rhegmatogenous retinal detachment without macular involvement by Eshita, Tadahiko, Shinoda, Kei, Kimura, Itaru, Kitamura, Shizuaki, Ishida, Susumu, Inoue, Makoto, Mashima, Yukihiko, Katsura, Hiroshi, Oguchi, Yoshihisa

“…To investigate retinal microcirculation changes in patients with rhegmatogenous retinal detachment (RRD). The tissue blood flow in the macular area was…”
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Use of High-speed, High-resolution Thermography to Evaluate the Tear Film Layer by MORI, ASAKO, OGUCHI, YOSHIHISA, OKUSAWA, YUKIO, ONO, MASAFUMI, FUJISHIMA, HIROSHI, TSUBOTA, KAZUO

“…To evaluate the tear film layer in patients with dry eye and in normal subjects by measuring the corneal temperature with infrared radiation thermography. One…”
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Analysis of Porcine Optineurin and Myocilin Expression in Trabecular Meshwork Cells and Astrocytes from Optic Nerve Head by Obazawa, Minoru, Mashima, Yukihiko, Sanuki, Naoko, Noda, Setsuko, Kudoh, Jun, Shimizu, Nobuyoshi, Oguchi, Yoshihisa, Tanaka, Yasuhiko, Iwata, Takeshi

“…To determine the cDNA sequences and analyze the expression of porcine optineurin and myocilin in trabecular meshwork cells (TMCs) and astrocytes from the optic…”
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Progression from Classical Oguchi Disease to Retinitis Pigmentosa after 50 Years by Nishiguchi, Koji M., Oguchi, Yoshihisa, Nakazawa, Toru

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Rapid quantification of the heteroplasmy of mutant mitochondrial DNAs in Leber's hereditary optic neuropathy using the Invader technology by Mashima, Yukihiko, Nagano, Makoto, Funayama, Tomoyo, Zhang, Qiang, Egashira, Tohru, Kudho, Jun, Shimizu, Nobuyoshi, Oguchi, Yoshihisa

“…Purpose: To quantify the degree of heteroplasmy of a mitochondrial DNA (mtDNA) mutation in Leber's hereditary optic neuropathy (LHON) a biplex Invader® assay…”
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Macular nerve fibers temporal to fovea may have a greater potential to recover function in patients with Leber's hereditary optic neuropathy by Mashima, Yukihiko, Sato, Enrique Adan, Ohde, Hisao, Oguchi, Yoshihisa

“…It is known that even after visual loss, younger patients with Leber's hereditary optic neuropathy (LHON) can recover vision. The purpose of this study was to…”
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Subthreshold UV Radiation-induced Peroxide Formation in Cultured Corneal Epithelial Cells: The Protective Effects of Lactoferrin by SHIMMURA, SHIGETO, SUEMATSU, MAKOTO, SHIMOYAMA, MASARU, TSUBOTA, KAZUO, OGUCHI, YOSHIHISA, SHIMURAI, YUZURU

“…Acute exposure to suprathreshold ultraviolet B radiation (UV-B) is known to cause photokeratitis resulting from the necrosis and shedding of corneal epithelial…”
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Myocilin Expression in the Astrocytes of the Optic Nerve Head by Noda, Setsuko, Mashima, Yukihiko, Obazawa, Minoru, Kubota, Ryo, Oguchi, Yoshihisa, Kudoh, Jun, Minoshima, Shinsei, Shimizu, Nobuyoshi

“…We investigated the expression of myocilin in the optic nerve head of porcine eyes by Western blotting and immunohistochemical staining. Myocilin was localized…”
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