Search Results - "OGRIS, EGON"
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Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation
Published in The EMBO journal (14-11-2012)“…Autophagy is a conserved process for the bulk degradation of cytoplasmic material. Triggering of autophagy results in the formation of double membrane‐bound…”
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2
Protein Phosphatase Methyl-Esterase PME-1 Protects Protein Phosphatase 2A from Ubiquitin/Proteasome Degradation
Published in PloS one (17-12-2015)“…Protein phosphatase 2A (PP2A) is a conserved essential enzyme that is implicated as a tumor suppressor based on its central role in phosphorylation-dependent…”
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3
The expression, localisation and interactome of pigeon CRY2
Published in Scientific reports (13-10-2021)“…Cryptochromes (CRY) are highly conserved signalling molecules that regulate circadian rhythms and are candidate radical pair based magnetoreceptors. Birds have…”
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4
A high sensitivity ZENK monoclonal antibody to map neuronal activity in Aves
Published in Scientific reports (22-01-2020)“…The transcription factor ZENK is an immediate early gene that has been employed as a surrogate marker to map neuronal activity in the brain. It has been used…”
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5
Budding yeast greatwall and endosulfines control activity and spatial regulation of PP2A(Cdc55) for timely mitotic progression
Published in PLoS genetics (2013)“…Entry into mitosis is triggered by cyclinB/Cdk1, whose activity is abruptly raised by a positive feedback loop. The Greatwall kinase phosphorylates proteins of…”
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6
The biophysical, molecular, and anatomical landscape of pigeon CRY4: A candidate light-based quantal magnetosensor
Published in Science advances (01-08-2020)“…The biophysical and molecular mechanisms that enable animals to detect magnetic fields are unknown. It has been proposed that birds have a light-dependent…”
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Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I
Published in Nature (04-05-2006)“…Segregation of homologous maternal and paternal centromeres to opposite poles during meiosis I depends on post-replicative crossing over between homologous…”
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PP2AC Phospho-Tyr307 Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2AC Modifications Including Leu309 Methylation
Published in Cell reports (Cambridge) (03-03-2020)“…Protein phosphatase 2A (PP2A) is an important regulator of signal transduction pathways and a tumor suppressor. Phosphorylation of the PP2A catalytic subunit…”
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9
Downregulation of Protein Phosphatase 2A Carboxyl Methylation and Methyltransferase May Contribute to Alzheimer Disease Pathogenesis
Published in Journal of neuropathology and experimental neurology (01-10-2004)“…ABαC, a major protein phosphatase 2A (PP2A) heterotrimeric enzyme, binds to and regulates the microtubule cytoskeleton and tau. We have shown that ABαC protein…”
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10
Generation of active protein phosphatase 2A is coupled to holoenzyme assembly
Published in PLoS biology (01-06-2007)“…Protein phosphatase 2A (PP2A) is a prime example of the multisubunit architecture of protein serine/threonine phosphatases. Until substrate-specific PP2A…”
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11
M-Track: detecting short-lived protein-protein interactions in vivo
Published in Nature methods (01-06-2012)“…A proximity assay based on methylation of interacting 'prey' proteins by a 'bait' fused to the histone lysine methyltransferase permits the detection of…”
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12
The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2A receptor
Published in Molecular pharmacology (01-04-2006)“…Many membrane proteins incur a folding problem during biosynthesis; only a fraction thereof is exported from the endoplasmic reticulum (ER), because quality…”
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13
Lamin A precursor induces barrier-to-autointegration factor nuclear localization
Published in Cell cycle (Georgetown, Tex.) (01-07-2010)“…Lamin A, a protein component of the nuclear lamina, is synthesized as a precursor named prelamin A, whose multi-step maturation process involves different…”
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14
Transcriptional Regulation by the Repressor of Estrogen Receptor Activity via Recruitment of Histone Deacetylases
Published in The Journal of biological chemistry (04-06-2004)“…Histone acetyltransferases and deacetylases are recruited by transcription factors and adapter proteins to regulate specific subsets of target genes. We were…”
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15
Budding Yeast Greatwall and Endosulfines Control Activity and Spatial Regulation of PP2ACdc55 for Timely Mitotic Progression
Published in PLoS genetics (04-07-2013)“…Entry into mitosis is triggered by cyclinB/Cdk1, whose activity is abruptly raised by a positive feedback loop. The Greatwall kinase phosphorylates proteins of…”
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16
Heterotrimeric G Protein-independent Signaling of a G Protein-coupled Receptor
Published in The Journal of biological chemistry (09-09-2005)“…The A2A adenosine receptor is a prototypical Gs-coupled receptor, but it also signals, e.g. to mitogen-activated protein (MAP) kinase, via a pathway that is…”
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17
Monoclonal antibodies specific for disease-associated point-mutants: lamin A/C R453W and R482W
Published in PloS one (13-05-2010)“…Disease-linked missense mutations can alter a protein's function with fatal consequences for the affected individual. How a single amino acid substitution in a…”
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18
A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo
Published in Genes & development (01-09-2003)“…Protein phosphatase 2A (PP2A) is an essential intracellular serine/threonine phosphatase containing a catalytic subunit that possesses the potential to…”
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A Protein Phosphatase Methylesterase (PME-1) Is One of Several Novel Proteins Stably Associating with Two Inactive Mutants of Protein Phosphatase 2A
Published in The Journal of biological chemistry (14-05-1999)“…Carboxymethylation of proteins is a highly conserved means of regulation in eukaryotic cells. The protein phosphatase 2A (PP2A) catalytic (C) subunit is…”
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20
Protein phosphatase 2A subunit assembly : the catalytic subunit carboxy terminus is important for binding cellular B subunit but not polyomavirus middle tumor antigen
Published in Oncogene (21-08-1997)“…The carboxy terminus of protein phosphatase 2A (PP2A) catalytic subunit is highly conserved. Seven out of the last nine residues, including two potential in…”
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