Search Results - "OGATA, ETSURO"

Ki26894, a novel transforming growth factor‐β type I receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line by Ehata, Shogo, Hanyu, Aki, Fujime, Makoto, Katsuno, Yoko, Fukunaga, Erina, Goto, Kouichiro, Ishikawa, Yuichi, Nomura, Kimie, Yokoo, Hiroshi, Shimizu, Toshiyuki, Ogata, Etsuro, Miyazono, Kohei, Shimizu, Kiyoshi, Imamura, Takeshi

“…Transforming growth factor (TGF)‐β signaling has been shown to promote tumor growth and metastasis in advanced cancer. Use of inhibitors of TGF‐β signaling may…”
Get full text

Functional in vivo optical imaging of tumor angiogenesis, growth, and metastasis prevented by administration of anti‐human VEGF antibody in xenograft model of human fibrosarcoma HT1080 cells by Hanyu, Aki, Kojima, Kiyotsugu, Hatake, Kiyohiko, Nomura, Kimie, Murayama, Hironori, Ishikawa, Yuichi, Miyata, Satoshi, Ushijima, Masaru, Matsuura, Masaaki, Ogata, Etsuro, Miyazawa, Keiji, Imamura, Takeshi

“…Angiogenesis plays a crucial role in cancer progression and metastasis. Thus, blocking tumor angiogenesis is potentially a universal approach to prevent tumor…”
Get full text

Post-operative breast cancer patients diagnosed with skeletal metastasis without bone pain had fewer skeletal-related events and deaths than those with bone pain by Koizumi, Mitsuru, Yoshimoto, Masataka, Kasumi, Fujio, Iwase, Takuji, Ogata, Etsuro

“…Skeletal metastases are often accompanied by bone pain. To investigate the clinical meaning of bone pain associated with skeletal metastasis in breast cancer…”
Get full text

CCAAT/Enhancer-Binding Protein Homologous Protein (CHOP) Regulates Osteoblast Differentiation by Shirakawa, Ken, Maeda, Shingo, Gotoh, Tomomi, Hayashi, Makoto, Shinomiya, Kenichi, Ehata, Shogo, Nishimura, Riko, Mori, Masataka, Onozaki, Kikuo, Hayashi, Hidetoshi, Uematsu, Satoshi, Akira, Shizuo, Ogata, Etsuro, Miyazono, Kohei, Imamura, Takeshi

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Similar changes of hypothalamic feeding‐regulating peptides mRNAs and plasma leptin levels in PTHrP‐, LIF‐secreting tumors‐induced cachectic rats and adjuvant arthritic rats by Suzuki, Hitoshi, Hashimoto, Hirofumi, Kawasaki, Makoto, Watanabe, Miho, Otsubo, Hiroki, Ishikura, Toru, Fujihara, Hiroaki, Ohnishi, Hideo, Onuma, Etsuro, Yamada‐Okabe, Hisafumi, Takuwa, Yoh, Ogata, Etsuro, Nakamura, Toshitaka, Ueta, Yoichi

“…Parathyroid hormone‐related protein (PTHrP) is a causative factor of humoral hypercalcemia in malignancy. However, it is difficult to explain the mechanism of…”
Get full text

Alfacalcidol Inhibits Bone Resorption and Stimulates Formation in an Ovariectomized Rat Model of Osteoporosis: Distinct Actions from Estrogen by Shiraishi, Ayako, Takeda, Satoshi, Masaki, Toshimi, Higuchi, Yoshinobu, Uchiyama, Yasushi, Kubodera, Noboru, Sato, Katsuhiko, Ikeda, Kyoji, Nakamura, Toshitaka, Matsumoto, Toshio, Ogata, Etsuro

“…Although alfacalcidol has been widely used for the treatment of osteoporosis in certain countries, its mechanism of action in bone, especially in the vitamin…”
Get full text

Parathyroid hormone‐related protein as a potential target of therapy for cancer‐associated morbidity by Ogata, Etsuro

“…BACKGROUND Proinflammatory cytokines are involved in the genesis of cancer‐associated cachexia. Parathyroid hormone‐related protein (PTHrP) is the causative…”
Get full text

Parathyroid Hormone-Related Protein Induces Cachectic Syndromes without Directly Modulating the Expression of Hypothalamic Feeding-Regulating Peptides by HASHIMOTO, Hirofumi, AZUMA, Yumiko, KAWASAKI, Makoto, FUJIHARA, Hiroaki, ONUMA, Etsuro, YAMADA-OKABE, Hisafumi, TAKUWA, Yoh, OGATA, Etsuro, UETA, Yoichi

“…Purpose: Parathyroid hormone-related protein (PTHrP) is a causative factor of humoral hypercalcemia of malignancy (HHM) and concurrent anorexia and wasting…”
Get full text

Humanized Monoclonal Antibody Against Parathyroid Hormone-related Protein Suppresses Osteolytic Bone Metastasis of Human Breast Cancer Cells Derived from MDA-MB-231 by SAITO, Hidemi, TSUNENARI, Toshiaki, ONUMA, Etsuro, SATO, Koh, OGATA, Etsuro, YAMADA-OKABE, Hisafumi

“…Background: Parathyroid hormone-related protein (PTHrP) has been implicated in bone metastasis. However, the effects on bone metastasis of blocking the PTHrP…”
Get full text

Hypothalamic Neuropeptides and Appetite Response in Anorexia-Cachexia Animal by UETA, Yoichi, HASHIMOTO, Hirofumi, ONUMA, Etsuro, TAKUWA, Yoh, OGATA, Etsuro

“…CACHEXIA, characterized by anorexia and marked weight loss, is a complex syndrome in patients with inflammatory disease and cancer. In particular, the…”
Get full text

Cyclin E as a Coactivator of the Androgen Receptor by Yamamoto, Ayako, Hashimoto, Yoshihiro, Kohri, Kenjiro, Ogata, Etsuro, Kato, Shige-aki, Ikeda, Kyoji, Nakanishi, Makoto

“…Androgens play an important role in the growth of prostate cancer, but the molecular mechanism that underlies development of resistance to anti-androgen…”
Get full text

Involvement of parathyroid hormone–related protein in experimental cachexia induced by a human lung cancer–derived cell line established from a bone metastasis specimen by Iguchi, Haruo, Onuma, Etsuro, Sato, Koh, Sato, Kanji, Ogata, Etsuro

“…Cachexia often causes deterioration in the quality of life in cancer patients; however, its mechanism remains poorly understood. Cachexia has often been…”
Get full text

Increased Renal Calcium Reabsorption by Parathyroid Hormone–Related Protein Is a Causative Factor in the Development of Humoral Hypercalcemia of Malignancy Refractory to Osteoclastic Bone Resorption Inhibitors by ONUMA, Etsuro, AZUMA, Yumiko, SAITO, Hidemi, TSUNENARI, Toshiaki, WATANABE, Toshihiko, HIRABAYASHI, Manabu, SATO, Koh, YAMADA-OKABE, Hisafumi, OGATA, Etsuro

“…Purpose: Bisphosphonate and calcitonin lower blood calcium in humoral hypercalcemia of malignancy (HHM) by suppressing osteoclastic bone resorption, but…”
Get full text

Progress in diagnosis and therapy: Calcium-phosphorus metabolism disorders by Ogata, Etsuro

Get more information

Involvement of cyclooxygenase‐2 in the tumor site‐dependent production of parathyroid hormone‐related protein in colon 26 carcinoma by Saito, Hidemi, Inagaki, Yukiko, Tsunenari, Toshiaki, Ura, Masako, Mizuno, Hideaki, Fujimoto‐Ouchi, Kaori, Onuma, Etsuro, Sato, Koh, Ogata, Etsuro, Yamada‐Okabe, Hisafumi

“…It has been shown that in the mouse colon 26 tumor model, tumors grown in the subcutis (subcutis colon 26) caused early onset of cachectic syndromes, whereas…”
Get full text

Vitamin D Hormone Inhibits Osteoclastogenesis In Vivo by Decreasing the Pool of Osteoclast Precursors in Bone Marrow by Shibata, Takeshi, Shira‐Ishi, Ayako, Sato, Takuya, Masaki, Toshimi, Sasaki, Aya, Masuda, Yoshiko, Hishiya, Akinori, Ishikura, Nobuyuki, Higashi, Sayumi, Uchida, Yasuhiro, Saito, Moto‐O, Ito, Masako, Ogata, Etsuro, Watanabe, Ken, Ikeda, Kyoji

“…Previous observations that vitamin D hormone induces the expression of the receptor activator of nuclear factor κB (NF‐κB) ligand (RANKL), thereby stimulating…”
Get full text

Bone in malignant disorders: introduction by Ogata, Etsuro

“…Patients harboring cancer and other tumors frequently exhibit such bone morbidity as metabolic bone diseases and bone metastases. Cancers produce and secrete…”
Get more information

Interactions between Cancer and Bone Marrow Cells Induce Osteoclast Differentiation Factor Expression and Osteoclast-like Cell Formation in Vitro by Chikatsu, Noriko, Takeuchi, Yasuhiro, Tamura, Yasuhiro, Fukumoto, Seiji, Yano, Kazuki, Tsuda, Eisuke, Ogata, Etsuro, Fujita, Toshiro

“…Cancer cells metastasized to bone induce osteoclastogenesis for bone destruction. Coculture of either mouse melanoma B16 or breast cancer Balb/c-MC cells with…”
Get full text

Parathyroid hormone–related protein (PTHrP) as a causative factor of cancer‐associated wasting: Possible involvement of PTHrP in the repression of locomotor activity in rats bearing human tumor xenografts by Onuma, Etsuro, Tsunenari, Toshiaki, Saito, Hidemi, Sato, Koh, Yamada‐Okabe, Hisafumi, Ogata, Etsuro

“…Nude rats bearing the LC‐6‐JCK human lung cancer xenograft displayed cancer‐associated wasting syndrome in addition to humoral hypercalcemia of malignancy. In…”
Get full text

Vitamin D-dependent recruitment of DNA-PK to the chromatinized negative vitamin D response element in the PTHrP gene is required for gene repression by vitamin D by Okazaki, Tomoki, Nishimori, Shigeki, Ogata, Etsuro, Fujita, Toshiro

“…The mechanism of transcriptional repression by nuclear hormone receptors, especially in the presence of the ligands, is largely unknown. We previously reported…”
Get full text