Search Results - "OFFNER, Nicolas"

The initiation factor eIF3-f is a major target for Atrogin1/MAFbx function in skeletal muscle atrophy by Lagirand-Cantaloube, Julie, Offner, Nicolas, Csibi, Alfredo, Leibovitch, Marie P, Batonnet-Pichon, Sabrina, Tintignac, Lionel A, Segura, Carlos T, Leibovitch, Serge A

“…In response to cancer, AIDS, sepsis and other systemic diseases inducing muscle atrophy, the E3 ubiquitin ligase Atrogin1/MAFbx (MAFbx) is dramatically…”
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The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity by Tourette, Cendrine, Farina, Francesca, Vazquez-Manrique, Rafael P, Orfila, Anne-Marie, Voisin, Jessica, Hernandez, Sonia, Offner, Nicolas, Parker, J Alex, Menet, Sophie, Kim, Jinho, Lyu, Jungmok, Choi, Si Ho, Cormier, Kerry, Edgerly, Christina K, Bordiuk, Olivia L, Smith, Karen, Louise, Anne, Halford, Michael, Stacker, Steven, Vert, Jean-Philippe, Ferrante, Robert J, Lu, Wange, Neri, Christian

“…The Wnt receptor Ryk is an evolutionary-conserved protein important during neuronal differentiation through several mechanisms, including γ-secretase cleavage…”
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RLIP, an Effector of the Ral GTPases, Is a Platform for Cdk1 to Phosphorylate Epsin during the Switch Off of Endocytosis in Mitosis by Rossé, Carine, L'Hoste, Sébastien, Offner, Nicolas, Picard, André, Camonis, Jacques

“…The Ral signaling pathway is critically involved in Ras-dependent oncogenesis. One of its key actors, RLIP/RalBP1, which participates in receptor endocytosis…”
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Trio Controls the Mature Organization of Neuronal Clusters in the Hindbrain by Backer, Stephanie, Hidalgo-Sanchez, Matias, Offner, Nicolas, Portales-Casamar, Elodie, Debant, Anne, Fort, Philippe, Gauthier-Rouviere, Cecile, Bloch-Gallego, Evelyne

“…During the embryonic development of the hindbrain, movements of neuronal clusters allow the formation of mature "pools", in particular for inferior olivary…”
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The pro-apoptotic activity of a vertebrate Bar-like homeobox gene plays a key role in patterning the Xenopus neural plate by limiting the number of chordin- and shh-expressing cells by Offner, Nicolas, Duval, Nathalie, Jamrich, Milan, Durand, Béatrice

“…Targeted disruption of effectors molecules of the apoptotic pathway have demonstrated the occurrence and magnitude of early programmed cell death (EPCD), a…”
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Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity by Parker, J Alex, Vazquez-Manrique, Rafael P, Tourette, Cendrine, Farina, Francesca, Offner, Nicolas, Mukhopadhyay, Arnab, Orfila, Anne-Marie, Darbois, Aurélie, Menet, Sophie, Tissenbaum, Heidi A, Neri, Christian

“…One of the current challenges of neurodegenerative disease research is to determine whether signaling pathways that are essential to cellular homeostasis might…”
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Meclizine is neuroprotective in models of Huntington's disease by Gohil, Vishal M, Offner, Nicolas, Walker, James A, Sheth, Sunil A, Fossale, Elisa, Gusella, James F, MacDonald, Marcy E, Neri, Christian, Mootha, Vamsi K

“…Defects in cellular energy metabolism represent an early feature in a variety of human neurodegenerative diseases. Recent studies have shown that targeting…”
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CLIPR-59: a protein essential for neuromuscular junction stability during mouse late embryonic development by Couesnon, Aurélie, Offner, Nicolas, Bernard, Véronique, Chaverot, Nathalie, Backer, Stéphanie, Dimitrov, Ariane, Perez, Franck, Molgó, Jordi, Bloch-Gallego, Evelyne

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CLIPR-59: a protein essential for neuromuscular junction stability during mouse late embryonic development by Couesnon, Aurélie, Offner, Nicolas, Bernard, Véronique, Chaverot, Nathalie, Backer, Stéphanie, Dimitrov, Ariane, Perez, Franck, Molgó, Jordi, Bloch-Gallego, Evelyne

“…CLIPR-59 is a new member of the cytoplasmic linker proteins (CLIP) family mainly localized to the trans-Golgi network. We show here that Clipr-59 expression in…”
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CLIPR-59: a protein essential for neuromuscular junction stability during mouse late embryonic development by Couesnon, Aurélie, Offner, Nicolas, Bernard, Véronique, Chaverot, Nathalie, Backer, Stéphanie, Dimitrov, Ariane, Perez, Franck, Molgó, Jordi, Bloch-Gallego, Evelyne

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The Wnt Receptor Ryk Reduces Neuronal and Cell Survival Capacity by Repressing FOXO Activity During the Early Phases of Mutant Huntingtin Pathogenicity: e1001895 by Tourette, Cendrine, Farina, Francesca, Vazquez-Manrique, Rafael P, Orfila, Anne-Marie, Voisin, Jessica, Hernandez, Sonia, Offner, Nicolas, Parker, J Alex, Menet, Sophie, Kim, Jinho, Lyu, Jungmok, Choi, Si Ho, Cormier, Kerry, Edgerly, Christina K, Bordiuk, Olivia L, Smith, Karen, Louise, Anne, Halford, Michael, Stacker, Steven, Vert, Jean-Philippe, Ferrante, Robert J, Lu, Wange, Neri, Christian

“…The Wnt receptor Ryk is an evolutionary-conserved protein important during neuronal differentiation through several mechanisms, including γ-secretase cleavage…”
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Meclizine is neuroprotective in models of Huntington's disease by GOHIL, Vishal M, OFFNER, Nicolas, WALKER, James A, SHETH, Sunil A, FOSSALE, Elisa, GUSELLA, James F, MACDONALD, Marcy E, NERI, Christian, MOOTHA, Vamsi K

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Compartmentalization of the functions and regulation of the mitotic cyclin Clb2 in S. cerevisiae by Eluère, Raïssa, Offner, Nicolas, Varlet, Isabelle, Motteux, Olivia, Signon, Laurence, Picard, André, Bailly, Eric, Simon, Marie-Noëlle

“…Orderly progression through the eukaryotic cell cycle is a complex process involving both regulation of cyclin dependent kinase activity and control of…”
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A contribution of the C. elegans model to the role of glial cells to the neuronal response by Vazquez, Raphael, Offner, Nicolas, Néri, Christian

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Propagation of polyglutamine agregates in normal cells by Offner, Nicolas, Vazquez, Raphael, Néri, Christian

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Cybip, a starfish cyclin B-binding protein, is involved in meiotic M-phase exit by Offner, Nicolas, Derancourt, Jean, Lozano, Jean-Claude, Schatt, Philippe, Picard, André, Peaucellier, Gérard

“…We designed a screen to identify starfish oocyte proteins able to bind monomeric cyclin B by affinity chromatography on a cyclin B splice variant displaying…”
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