Search Results - "OEI, Yoko"

IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines by Tahtinen, Siri, Tong, Ann-Jay, Himmels, Patricia, Oh, Jaehak, Paler-Martinez, Andres, Kim, Leesun, Wichner, Sara, Oei, Yoko, McCarron, Mark J., Freund, Emily C., Amir, Zhainib Adel, de la Cruz, Cecile C., Haley, Benjamin, Blanchette, Craig, Schartner, Jill M., Ye, Weilan, Yadav, Mahesh, Sahin, Ugur, Delamarre, Lélia, Mellman, Ira

“…The use of lipid-formulated RNA vaccines for cancer or COVID-19 is associated with dose-limiting systemic inflammatory responses in humans that were not…”
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CSF-1R inhibition alters macrophage polarization and blocks glioma progression by Pyonteck, Stephanie M, Akkari, Leila, Schuhmacher, Alberto J, Bowman, Robert L, Sevenich, Lisa, Quail, Daniela F, Olson, Oakley C, Quick, Marsha L, Huse, Jason T, Teijeiro, Virginia, Setty, Manu, Leslie, Christina S, Oei, Yoko, Pedraza, Alicia, Zhang, Jianan, Brennan, Cameron W, Sutton, James C, Holland, Eric C, Daniel, Dylan, Joyce, Johanna A

“…The authors provide preclinical testing of a CSFR-1 inhibitor in proneural glioma models. The compound targets macrophages in the tumor microenvironment rather…”
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Dexamethasone premedication suppresses vaccine-induced immune responses against cancer by Vormehr, Mathias, Lehar, Sophie, Kranz, Lena M., Tahtinen, Siri, Oei, Yoko, Javinal, Vincent, Delamarre, Lélia, Walzer, Kerstin C., Diken, Mustafa, Kreiter, Sebastian, Mellman, Ira, Sahin, Ugur, Schartner, Jill M., Türeci, Özlem

“…Glucocorticosteroids (GCS) have an established role in oncology and are administered to cancer patients in routine clinical care and in drug development trials…”
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Bioluminescent imaging (BLI) to improve and refine traditional murine models of tumor growth and metastasis by Jenkins, Darlene E, Oei, Yoko, Hornig, Yvette S, Yu, Shang-Fan, Dusich, Joan, Purchio, Tony, Contag, Pamela R

“…Bioluminescent imaging (BLI) permits sensitive in vivo detection and quantification of cells specifically engineered to emit visible light. Three stable human…”
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Human Endothelial Cell Life Extension by Telomerase Expression by Yang, Jiwei, Chang, Edwin, Cherry, Athena M., Bangs, Charles D., Oei, Yoko, Bodnar, Andrea, Bronstein, Adrienne, Chiu, Choy-Pik, Herron, G. Scott

“…Normal human endothelial cells, like other somatic cells in culture, divide a limited number of times before entering a nondividing state called replicative…”
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CHIR-258 Is Efficacious in A Newly Developed Fibroblast Growth Factor Receptor 3–Expressing Orthotopic Multiple Myeloma Model in Mice by XIAOHUA XIN, ABRAMS, Tinya J, TRUDEL, Suzanne, JALLAL, Bahija, MENDEL, Dirk B, HEISE, Carla C, HOLLENBACH, Paul W, RENDAHL, Katherine G, YAN TANG, OEI, Yoko A, EMBRY, Millicent G, SWINARSKI, Debbie E, GARRETT, Evelyn N, PRYER, Nancy K

“…Purpose: The ectopically expressed and deregulated fibroblast growth factor receptor 3 (FGFR3) results from a t(4;14) chromosomal translocation that occurs in…”
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CHIR-258: A Potent Inhibitor of FLT3 Kinase in Experimental Tumor Xenograft Models of Human Acute Myelogenous Leukemia by Lopes de Menezes, Daniel E, Peng, Jing, Garrett, Evelyn N, Louie, Sharianne G, Lee, Sang H, Wiesmann, Marion, Tang, Yan, Shephard, Lee, Goldbeck, Cheryl, Oei, Yoko, Ye, Helen, Aukerman, Sharon L, Heise, Carla

“…Purpose: Fms-like tyrosine kinase 3 (FLT3) encodes a receptor tyrosine kinase (RTK) for which activating mutations have been identified in a proportion of…”
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Imaging of bioluminescent LNCaP-luc-M6 Tumors: A new animal model for the study of metastatic human prostate cancer by Scatena, Caroline D., Hepner, Mischa A., Oei, Yoko A., Dusich, Joan M., Yu, Shang-Fan, Purchio, Tony, Contag, Pamela R., Jenkins, Darlene E.

“…BACKGROUND Animal experiments examining hormone‐sensitive metastatic prostate cancer using the human LNCaP cell line have been limited to endpoint analyses. To…”
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Novel Robust Hepatitis C Virus Mouse Efficacy Model by QING ZHU, OEI, Yoko, MENDEL, Dirk B, GARRETT, Evelyn N, PATAWARAN, Montesa B, HOLLENBACH, Paul W, AUKERMAN, Sharon L, WEINER, Amy J

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Abstract 3629: BLZ945, a selective c-fms (CSF-1R) kinase inhibitor for the suppression of tumor-induced osteolytic lesions in bone by Wiesmann, Marion, Daniel, Dylan L., Pryer, Nancy, Sutton, James, Sung, Victoria, Wang, Tao, Jeffry, Ursula, Oei, Yoko, Kaufman, Susan, Lenahan, William, Lee, Isabelle, Huh, Kay, Sim, Janet

“…Abstract Aberrant activation of osteoclasts due to bone metastasis causes osteolysis, skeletal-related events and severe pain in cancer patients…”
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CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8+ T cells by Strachan, Debbie C, Ruffell, Brian, Oei, Yoko, Bissell, Mina J, Coussens, Lisa M, Pryer, Nancy, Daniel, Dylan

“…Increased numbers of tumor-infiltrating macrophages correlate with poor disease outcome in patients affected by several types of cancer, including breast and…”
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Homeostatic functions of monocytes and interstitial lung macrophages are regulated via collagen domain-binding receptor LAIR1 by Keerthivasan, Shilpa, Şenbabaoğlu, Yasin, Martinez-Martin, Nadia, Husain, Bushra, Verschueren, Erik, Wong, Anne, Yang, Yeqing Angela, Sun, Yonglian, Pham, Victoria, Hinkle, Trent, Oei, Yoko, Madireddi, Shravan, Corpuz, Racquel, Tam, Lucinda, Carlisle, Samantha, Roose-Girma, Merone, Modrusan, Zora, Ye, Zhengmao, Koerber, James T., Turley, Shannon J.

“…Myeloid cells encounter stromal cells and their matrix determinants on a continual basis during their residence in any given organ. Here, we examined the…”
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Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivo detection of mammary tumors and multiple metastases in immune deficient mice by Jenkins, Darlene E, Hornig, Yvette S, Oei, Yoko, Dusich, Joan, Purchio, Tony

“…Our goal was to generate xenograft mouse models of human breast cancer based on luciferase-expressing MDA-MB-231 tumor cells that would provide rapid mammary…”
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Discovery of Potent and Selective Antibody–Drug Conjugates with Eg5 Inhibitors through Linker and Payload Optimization by Karpov, Alexei S, Nieto-Oberhuber, Cristina M, Abrams, Tinya, Beng-Louka, Edwige, Blanco, Enrique, Chamoin, Sylvie, Chene, Patrick, Dacquignies, Isabelle, Daniel, Dylan, Dillon, Michael P, Doumampouom-Metoul, Lionel, Drosos, Nikolaos, Fedoseev, Pavel, Furegati, Markus, Granda, Brian, Grotzfeld, Robert M, Hess Clark, Suzanna, Joly, Emilie, Jones, Darryl, Lacaud-Baumlin, Marion, Lagasse-Guerro, Stephanie, Lorenzana, Edward G, Mallet, William, Martyniuk, Piotr, Marzinzik, Andreas L, Mesrouze, Yannick, Nocito, Sandro, Oei, Yoko, Perruccio, Francesca, Piizzi, Grazia, Richard, Etienne, Rudewicz, Patrick J, Schindler, Patrick, Velay, Mélanie, Venstrom, Kristine, Wang, Peiyin, Zurini, Mauro, Lafrance, Marc

“…Targeted antimitotic agents are a promising class of anticancer therapies. Herein, we describe the development of a potent and selective antimitotic Eg5…”
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Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivodetection of mammary tumors and multiple metastases in immune deficient mice by Jenkins, Darlene E, Hornig, Yvette S, Oei, Yoko, Dusich, Joan, Purchio, Tony

“…Abstract Introduction Our goal was to generate xenograft mouse models of human breast cancer based on luciferase-expressing MDA-MB-231 tumor cells that would…”
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CHIR-258 Efficacy in a Newly Developed Preclinical Bone Marrow Model of t(4;14) Multiple Myeloma by Xin, Xiaohua, Tang, Yan, Oei, Yoko, Ye, Helen, Menezes, Daniel, Rendahl, Katherine, Hollenbach, Paul, Pryer, Nancy, Trudel, Suzanne, Mendel, Dirk, Jallal, Bahija, Heise, Carla

“…Multiple myeloma (MM) remains a fatal hematological malignancy due to the development of drug resistance to conventional high-dosage chemotherapy. It has been…”
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CHIR258: A Multitargeted Growth Factor Receptor Tyrosine Kinase (RTK) Inhibitor Induces Significant Apoptosis of Human FLT3 ITD Acute Myelogenous Leukemia Cells In Vitro and in Vivo by Menezes, Daniel L., Wiesmann, Marion, Lee, Sang Hoon, Lee, Isabelle, Peng, Jing, Tang, Yan, Ye, Helen, Oei, Yoko, Goldbeck, Cheryl, Garrett, Evelyn N., Heise, Carla

“…Fms-like tyrosine kinase 3 (FLT3) encodes a receptor tyrosine kinase (RTK) for which activating mutations have been identified in a proportion of acute…”
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An Antibody-Catalyzed [2,3]-Elimination Reaction by Yoon, Seung Soo, Oei, Yoko, Sweet, Elizabeth, Schultz, Peter G

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Antibodies with Thiol-S-Transferase Activity by Fan, Erkang, Oei, Yoko, Sweet, Elizabeth, Uno, Tetsuo, Schultz, Peter G

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