Search Results - "ODA, Hideaki"

Depletion of mitochondrial fission factor DRP1 causes increased apoptosis in human colon cancer cells by Inoue-Yamauchi, Akane, Oda, Hideaki

“…► DRP1 is required for mitochondrial fission in colon cancer cells. ► DRP1 participates in inhibition of colon cancer cell apoptosis. ► DRP1 can inhibit…”
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Neutral Solution Low in Glucose Degradation Products Is Associated with Less Peritoneal Fibrosis and Vascular Sclerosis in Patients Receiving Peritoneal Dialysis by Kawanishi, Kunio, Honda, Kazuho, Tsukada, Misao, Oda, Hideaki, Nitta, Kosaku

“…The effects of novel biocompatible peritoneal dialysis (PD) solutions on human peritoneal membrane pathology have yet to be determined. Quantitative evaluation…”
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UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes by Sera, Yasuyuki, Nakata, Yuichiro, Ueda, Takeshi, Yamasaki, Norimasa, Koide, Shuhei, Kobayashi, Hiroshi, Ikeda, Ken-ichiro, Kobatake, Kohei, Iwasaki, Masayuki, Oda, Hideaki, Wolff, Linda, Kanai, Akinori, Nagamachi, Akiko, Inaba, Toshiya, Sotomaru, Yusuke, Ichinohe, Tatsuo, Koizumi, Miho, Miyakawa, Yoshihiko, Honda, Zen-ichiro, Iwama, Atsushi, Suda, Toshio, Takubo, Keiyo, Honda, Hiroaki

“…Epigenetic regulation is essential for the maintenance of the hematopoietic system, and its deregulation is implicated in hematopoietic disorders. In this…”
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Immunochemical analysis of iron transporters and M2 macrophages in ovarian endometrioma and clear cell adenocarcinoma by Akashi, Keiko, Nagashima, Yoji, Tabata, Tsutomu, Oda, Hideaki

“…The association between iron ions and endometriosis-associated ovarian cancer (EAOC) has been previously investigated to elucidate EAOC carcinogenesis;…”
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Advanced glycation end products suppress lysyl oxidase and induce bone collagen degradation in a rat model of renal osteodystrophy by Aoki, Chiharu, Uto, Kenta, Honda, Kazuho, Kato, Yoshiharu, Oda, Hideaki

“…Renal osteodystrophy (ROD) is a major problem in patients with renal insufficiency. The present study was designed to elucidate the role of bone collagen…”
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An Autopsy Case of Arrhythmogenic Right Ventricular Cardiomyopathy　― Radiological/Pathological Comparison by Uto, Kenta, Nagao, Michinobu, Kikuchi, Noriko, Onizuka, Hiromi, Yoshizawa, Saeko, Hagiwara, Nobuhisa, Oda, Hideaki

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Podocyte and endothelial injury in focal segmental glomerulosclerosis: an ultrastructural analysis by Taneda, Sekiko, Honda, Kazuho, Ohno, Mayuko, Uchida, Keiko, Nitta, Kosaku, Oda, Hideaki

“…Podocyte injury contributes to the development of focal segmental glomerulosclerosis (FSGS). Endocapillary hypercellularity, which is one of the pathological…”
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Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2 by Ueda, Takeshi, Nagamachi, Akiko, Takubo, Keiyo, Yamasaki, Norimasa, Matsui, Hirotaka, Kanai, Akinori, Nakata, Yuichiro, Ikeda, Kenichiro, Konuma, Takaaki, Oda, Hideaki, Wolff, Linda, Honda, Zen-ichiro, Wu, Xudong, Helin, Kristian, Iwama, Atsushi, Suda, Toshio, Inaba, Toshiya, Honda, Hiroaki

“…We previously reported that deficiency for Samd9L, which was cloned as a candidate gene for −7/7q− syndrome, accelerated leukemia cooperatively with enhanced…”
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A Case of Tailgut Cyst Successfully Resected with Laparoscopic Approach by Kono, Teppei, Yoshimatsu, Kazuhiko, Yokokawa, Hideyuki, Fukuya, Yuji, Oda, Hideaki, Shiozawa, Shunichi

“…Tailgut Cyst is a rare lesion occurring in the retrorectal space. A complete resection is necessary for diagnosis and treatment without morbidity. Here we…”
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Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression by Ueda, Takeshi, Nakata, Yuichiro, Nagamachi, Akiko, Yamasaki, Norimasa, Kanai, Akinori, Sera, Yasuyuki, Sasaki, Masato, Matsui, Hirotaka, Honda, Zen-ichiro, Oda, Hideaki, Wolff, Linda, Inaba, Toshiya, Honda, Hiroaki

“…Polycomb repressive complex 2 (PRC2) catalyzes the monomethylation, dimethylation, and trimethylation of histone H3 Lys27 (H3K27) and acts as a central…”
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Identification of cooperative genes for E2A‐PBX1 to develop acute lymphoblastic leukemia by Sera, Yasuyuki, Yamasaki, Norimasa, Oda, Hideaki, Nagamachi, Akiko, Wolff, Linda, Inukai, Takeshi, Inaba, Toshiya, Honda, Hiroaki

“…E2A‐PBX1 is a chimeric gene product detected in t(1;19)‐bearing acute lymphoblastic leukemia (ALL) with B‐cell lineage. To investigate the leukemogenic…”
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Eicosapentaenoic acid restores diabetic tubular injury through regulating oxidative stress and mitochondrial apoptosis by Taneda, Sekiko, Honda, Kazuho, Tomidokoro, Kimiko, Uto, Kenta, Nitta, Kosaku, Oda, Hideaki

“…The present study was designed to elucidate a possible mechanism of hyperglycemia-induced tubular injury and to examine a therapeutic potential of dietary…”
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Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis by SHIDARA, Yujiro, YAMAGATA, Kumi, KANAMORI, Takashi, NAKANO, Kazutoshi, KWONG, Jennifer Q, MANFREDI, Giovanni, ODA, Hideaki, OHTA, Shigeo

“…The role of mitochondrial dysfunction in cancer has been a subject of great interest and much ongoing investigation. Although most cancer cells harbor somatic…”
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Pathology of encapsulating peritoneal sclerosis by HONDA, Kazuho, ODA, Hideaki

“…Pathology findings of encapsulating peritoneal sclerosis (EPS) are reviewed to establish histologic criteria for a diagnosis of EPS. The typical macroscopic…”
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Acquired deficiency of A20 results in rapid apoptosis, systemic inflammation, and abnormal hematopoietic stem cell function by Nagamachi, Akiko, Nakata, Yuichiro, Ueda, Takeshi, Yamasaki, Norimasa, Ebihara, Yasuhiro, Tsuji, Kohichiro, Honda, Zen-ichiro, Takubo, Keiyo, Suda, Toshio, Oda, Hideaki, Inaba, Toshiya, Honda, Hiroaki

“…A20 is a negative regulator of NF-κB, and mutational loss of A20 expression is involved in the pathogenesis of autoimmune diseases and B-cell lymphomas. To…”
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Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency by Ikeda, Kenichiro, Ueda, Takeshi, Yamasaki, Norimasa, Nakata, Yuichiro, Sera, Yasuyuki, Nagamachi, Akiko, Miyama, Takahiko, Kobayashi, Hiroshi, Takubo, Keiyo, Kanai, Akinori, Oda, Hideaki, Wolff, Linda, Honda, Zen-ichiro, Ichinohe, Tatsuo, Matsubara, Akio, Suda, Toshio, Inaba, Toshiya, Honda, Hiroaki

“…Polycomb repressive complex 2 (PRC2) participates in transcriptional repression through methylation of histone H3K27. The WD-repeat protein embryonic ectoderm…”
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Crk‐associated substrate lymphocyte type regulates myeloid cell motility and suppresses the progression of leukemia induced by p210Bcr/Abl by Seo, Sachiko, Nakamoto, Tetsuya, Takeshita, Masataka, Lu, Jun, Sato, Tomohiko, Suzuki, Takahiro, Kamikubo, Yasuhiko, Ichikawa, Motoshi, Noda, Masaki, Ogawa, Seishi, Honda, Hiroaki, Oda, Hideaki, Kurokawa, Mineo

“…The p210Bcr/Abl and p190Bcr/Abl fusion oncoproteins are known to cause chronic myelogenous leukemia (CML) and acute lymphoblastic leukemia (ALL). Bcr/Abl…”
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Dok-1 and Dok-2 are negative regulators of T cell receptor signaling by Yasuda, Tomoharu, Bundo, Kenji, Hino, Ayako, Honda, Kazuho, Inoue, Akane, Shirakata, Masaki, Osawa, Mitsujiro, Tamura, Toshiki, Nariuchi, Hideo, Oda, Hideaki, Yamamoto, Tadashi, Yamanashi, Yuji

“…Interaction of the TCR complex with self- or foreign peptides is a central event in the immune responses. Upon TCR stimulation, a protein–tyrosine kinase…”
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Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia by Nakata, Yuichiro, Ueda, Takeshi, Nagamachi, Akiko, Yamasaki, Norimasa, Ikeda, Ken-ichiro, Sera, Yasuyuki, Takubo, Keiyo, Kanai, Akinori, Oda, Hideaki, Sanada, Masashi, Ogawa, Seishi, Tsuji, Kohichiro, Ebihara, Yasuhiro, Wolff, Linda, Honda, Zen-ichiro, Suda, Toshio, Inaba, Toshiya, Honda, Hiroaki

“…Chronic myelomonocytic leukemia (CMML) is a hematological malignancy characterized by uncontrolled proliferation of dysplastic myelomonocytes and frequent…”
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Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma by Mashima, Ryuichi, Honda, Kazuho, Yang, Yi, Morita, Yohei, Inoue, Akane, Arimura, Sumimasa, Nishina, Hiroshi, Ema, Hideo, Nakauchi, Hiromitsu, Seed, Brian, Oda, Hideaki, Yamanashi, Yuji

“…Histiocytic sarcoma (HS), a rare hematological malignancy, is an aggressive neoplasm that responds poorly to therapy. The molecular etiology and pathology of…”
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