Search Results - "OCSOVSZKI, Imre"
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Chemical composition, antioxidant and anticancer activity of licorice from Fruska Gora locality
Published in Industrial crops and products (01-02-2018)“…•Phytochemical and biological analysis of licorice from Fruska Gora were investigated.•The highest content of bioactive compounds was observed in the extract…”
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2
Synthesis and In Vitro Antitumor Activity of Naringenin Oxime and Oxime Ether Derivatives
Published in International journal of molecular sciences (02-05-2019)“…Naringenin is one of the most abundant dietary flavonoids exerting several beneficial biological activities. Synthetic modification of naringenin is of…”
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3
Investigation of natural phenanthrenes and the antiproliferative potential of juncusol in cervical cancer cell lines
Published in Phytomedicine (Stuttgart) (01-05-2019)“…Phenanthrenes isolated from Juncus species possess different biological activities, including antiproliferative and antimigratory effects. In this study, nine…”
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4
A versatile transposon-based technology to generate loss- and gain-of-function phenotypes in the mouse liver
Published in BMC biology (01-04-2022)“…Understanding the contribution of gene function in distinct organ systems to the pathogenesis of human diseases in biomedical research requires modifying gene…”
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5
A click approach to novel D-ring-substituted 16α-triazolylestrone derivatives and characterization of their antiproliferative properties
Published in PloS one (18-02-2015)“…A simple and efficient synthesis of novel, D-ring substituted estrone derivatives containing a 16α-triazolyl moiety is described. Two epimeric azido alcohols…”
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6
Antiproliferative Properties of Newly Synthesized 19-Nortestosterone Analogs Without Substantial Androgenic Activity
Published in Frontiers in pharmacology (27-07-2018)“…19-Nortestosterone C-17 epimers with prominent antiproliferative properties have been previously described. In our present study, five novel…”
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7
ACTH- and cortisol-associated neutrophil modulation in coronary artery disease patients undergoing stent implantation
Published in PloS one (14-08-2013)“…Psychosocial stress and activation of neutrophil granulocytes are increasingly recognized as major risk factors of coronary artery disease (CAD), but the…”
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8
Investigation of the Antiproliferative Properties of Natural Sesquiterpenes from Artemisia asiatica and Onopordum acanthium on HL-60 Cells in Vitro
Published in International journal of molecular sciences (01-02-2016)“…Plants and plant extracts play a crucial role in the research into novel antineoplastic agents. Four sesquiterpene lactones, artecanin (1),…”
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Microcirculatory consequences of limb ischemia/reperfusion in ovariectomized rats treated with zoledronic acid
Published in Journal of orthopaedic surgery and research (04-04-2019)“…Nitrogen-containing bisphosphonates (BIS) are potent therapeutics in osteoporosis, but their use may result in osteonecrotic side-effects in the maxillofacial…”
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10
Anticancer and multidrug resistance-reversal effects of solanidine analogs synthetized from pregnadienolone acetate
Published in Molecules (Basel, Switzerland) (17-02-2014)“…A set of solanidine analogs with antiproliferative properties were recently synthetized from pregnadienolone acetate, which occurs in Nature. The aim of the…”
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11
Antitumor Activity of Alkaloids Derived from Amaryllidaceae Species
Published in In vivo (Athens) (01-01-2009)“…The aim of the present study was to investigate the anticancer properties of five alkaloids isolated from Amaryllidaceae, including the inhibitory effect on…”
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12
Differential Effect of Phenothiazines on MRP1 and P-Glycoprotein Activity
Published in In vivo (Athens) (01-11-2009)“…Background: Overexpression of ATP-binding cassette (ABC) transporters such as P-glycoprotein (P-gp), multidrug resistance-associated protein 1 (MRP1) or breast…”
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13
Screening of Some Saponins and Phenolic Components of Tribulus terrestris and Smilax excelsa as MDR Modulators
Published in In vivo (Athens) (01-07-2009)“…Background: Cytotoxic activity of saponins and phenolic compounds have been described in the literature, but no reports were found on their multidrug…”
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14
2-(3-Aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides: A novel cluster of tumor-specific cytotoxins which reverse multidrug resistance
Published in Bioorganic & medicinal chemistry (01-06-2009)“…The quinoxaline derivatives 3 possess one or more of the following features, namely antiproliferative activities, selective cytotoxicity to neoplasms than…”
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15
Investigation of cytotoxic activity on human cancer cell lines of arborinine and furanoacridones isolated from Ruta graveolens
Published in Planta medica (01-01-2007)“…The cytotoxic effects of a series of furanoacridones isolated from Ruta graveolens L. (Rutaceae) and of two further acridone alkaloids (arborinine and…”
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Antitumour Properties of Acridone Alkaloids on a Murine Lymphoma Cell Line
Published in Anticancer research (01-09-2008)“…The aim of the present study was to investigate the anticancer properties of a set of furanoacridone alkaloids, arborinine and evoxanthine, including the…”
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17
Different administration schedules of darbepoetin alfa affect oxidized and reduced glutathione levels to a similar extent in 5/6 nephrectomized rats
Published in Clinical and experimental nephrology (01-08-2013)“…Background The development of erythropoiesis-stimulating agents (ESAs) with extended serum half-lives has allowed marked prolongation of the administration…”
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18
MDR-reversal Activity of Chalcones
Published in In vivo (Athens) (01-05-2008)“…The ability of 11 chalcones with 3,4,5-trimethoxy substitution on ring A to inhibit the transport activity of P-glycoprotein was studied. Flow cytometry was…”
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19
Flow cytometric analysis of procalcitonin expression in human monocytes and granulocytes
Published in Immunology letters (03-12-2002)“…Procalcitonin (PCT), a precursor of calcitonin is a useful indicator of severe systemic infection and sepsis. For a better understanding of the…”
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20
Tumour-specific Cytotoxicity and MDR-reversal Activity of Dihydropyridines
Published in In vivo (Athens) (01-09-2006)“…The ability of 41 1,4-diphenyl-1,4-dihydropyridine derivatives to inhibit the transport activity of P-glycoprotein were studied by flow cytometry in a…”
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